Serum fetuin-A and RANKL levels in patients with early stage breast cancer

Background: Breast cancer (BC) is the primary cause of mortality due to cancer in females around the world. Fetuin-A is known to increase metastases over signals and peroxisomes related with growing. Receptor activator of nuclear factor-kB ligand (RANKL) takes part in cell adhesion, and RANKL inhibition is used in the management of cancer. We aimed to examine the relationship between serum fetuin-A, RANKL levels, other laboratory parameters and clinical findings in women diagnosed with early stage BC, in our population. Methods: Women having early stage BC (n=117) met our study inclusion criteria as they had no any anti-cancer therapy before. Thirty-seven healthy women controls were also confirmed with breast examination and ultrasonography and/or mammography according to their ages. Serum samples were stored at -80 °C and analysed via ELISA. Results: Median age of the patients was 53 (range: 57-86) while it was 47 (range: 23-74) in the healthy group. Patients had lower high-density lipoprotein levels (p=0.002) and higher neutrophil counts (p=0.014). Fetuin-A and RANKL levels did not differ between the groups (p=0.116 and p=0.439, respectively) but RANKL leves were found to be lower in the favorable histological subtypes (p=0.04). Conclusions: In this study, we found no correlation between serum fetuin-A levels and clinical findings in patients diagnosed with early stage BC. However, RANKL levels are found to be lower in subgroups with favorable histopathologic subtypes such as tubular, papillary and mucinous BC and there was statistically significant difference

The Perspectives of Fans on Clubs’ Values in Developing Football Economy: The Case of Bucaspor

In this research, it is aimed to identify the perspectives of fans to the football clubs’ values. In this respect, a scale of 8 sub dimension and 35 statements is composed and a questionnaire with 351 fans is realized. As a result, it is detected that perception of the physical condition of the stadium in which Bucaspor plays and the quality of the club’s licensed products are relatively close to high, however ticket and combined ticket prices are relatively high. Besides it is concluded that main reason of low participation of the fans in the matches is Passolig application which is carried out in 2014-2015 season and that sponsors have considerable importance in sporting and financial success of the club. As a conclusion the obtained data are evaluated and suggestions for strengthening the financial structure of the club are presented

The Perspectives of Fans on Clubs’ Values in Developing Football Economy: The Case of Bucaspor

Çalışmada taraftarların, futbol kulüplerinin sahip oldukları değerlere yönelik bakış açılarının tanımlanması amaçlanmıştır. Bu amaçla 8 alt boyut ve 35 ifadeden oluşan bir ölçek oluşturulmuş ve 351 taraftar üzerinde anket uygulaması gerçekleştirilmiştir. Araştırma sonucunda, Bucaspor kulübünün maçlarını oynadığı stadyumunun fiziksel özelliklerinin ve lisanslı ürünlerinin kalite algısının göreceli olarak yükseğe yakın düzeyde olduğu, bilet ve kombine fiyatlarının ise, göreceli olarak yüksek olduğu bulgulanmıştır. Ayrıca, taraftarların maça katılım düzeylerinin düşük seviyede bulunmasının temel nedeninin 2014-2015 sezonu ile hayata geçen Passolig uygulaması olduğu ve kulübün sportif ve finansal başarısında sponsorların oldukça önemli bir etkisinin bulunduğu sonucuna ulaşılmıştır. Çalışma sonucunda elde edilen bulgular değerlendirilmiş ve kulübün finansal yapısının güçlendirilebilmesine yönelik öneriler sunulmuştur

A study on the effects of political marketing practices upon first time voters

Siyasal pazarlama; siyasi partilerin ve adayların, seçim dönemlerinde seçimi kazanmak ya da hedefledikleri oy seviyesine ulaşmak için gerçekleştirdikleri çabaların tümüdür. Günümüzde seçmenler nezdinde ideoloji kavramı önemini yitirmekte ve siyasi partiler birbirlerine benzer konularla seçmenlere yönelmektedirler. Seçmenlerin, benzer parti programları ve vaatler karşısında tercihlerini belirli bir siyasi parti veya adaya yöneltebilmeleri için, siyasi parti ve adayların kendilerini seçmenlere doğru şekilde ifade etmeleri gerekmektedir. Bu çalışmanın amacı, siyasal pazarlama çabalarının ilk kez oy kullanacak seçmenlerin tercihlerine yönelik bir etkisinin olup olmadığının belirlenmesidir. Bu amaca yönelik, İzmir ili Buca ilçesinde yer alan 10 adet lisenin son sınıf öğrencilerine anket uygulanmış ve elde edilen bulgular değerlendirilmiştir.Political marketing is the all of the effort that political parties and candidates make to win the election or reach the target vote rate. Nowadays, ideology concept loses its importance for voters and political parties head voters with similar issues. In order to direct preferences of voters to a specific political party or candidate against similar programs and promises, political parties and candidates are required to express themselves appropriately to the voters. The aim of this paper is to investigate whether political marketing effort have effect on the preferences of first time voters. For this purpose, a survey is conducted to students of 10 high school that take place in Izmir, Buca and the results were evaluated