HST and ground-based eclipse observations of V2051 Ophiuchi: Binary parameters

We report on high-speed eclipse photometry of the dwarf nova V2051 Oph while it was in a low brightness state, at B ~ 16.2 mag. In comparison to the average IUE spectra, the ultraviolet continuum and emission lines appear reduced by factors of, respectively, ~4 and ~5. Flickering activity is mostly suppressed and the lightcurve shows the eclipse of a compact white dwarf at disc centre which contributes ~60 per cent of the total light at 3900--4300 A. We use measurements of contact phases in the eclipse lightcurve to derive the binary geometry and to estimate masses and relevant dimensions. We find a mass ratio of q= 0.19+/-0.03 and an inclination of i= 83+/-2 degrees. The masses of the component stars are M_1 = 0.78+/-0.06 M_dot and M_2 = 0.15+/-0.03 M_dot. Our photometric model predicts K_1 = 83+/-12 km/s and K_2= 435+/-11 km/s. The predicted value of K_1 is in accordance with the velocity amplitude obtained from the emission lines after a correction for asymmetric line emission in the disc is made (Watts et al. 1986). The secondary of V2051 Oph is significantly more massive than the secondaries of the other ultra-short period dwarf novae. V2051 Oph is probably a relatively young system, whose secondary star had not enough time to evolve out of thermal equilibrium.Comment: 16 pages, 7 postscript figures, coded using MNRAS latex style. To appear in Monthly Notices of the Royal Astronomical Society. Revised version with changes in section 4.3. For related papers and files see ftp://fsc01.fsc.ufsc.br/pub/bap and http://www.fsc.ufsc.br/~astr

Systematic review and meta-analysis on physical barriers to prevent root dentin demineralization.

The present review systematically analyzed in vitro and in situ studies investigating physical diffusion barriers (sealants, desensitizer or adhesives) to prevent the development or the progression of root (dentin) demineralization. Three electronic databases (PubMed-Medline, CENTRAL, Ovid-EMBASE) were screened for studies from 1946 to 2022. Cross-referencing was used to identify further articles. Article selection and data abstraction were done in duplicate. Languages were not restricted. The type of outcome was not restricted, and their mean differences (MD) were calculated using fixed- or random-effects models. Risk of Bias was graded using Risk of Bias 2.0 tool. From 171 eligible studies, 34 were selected for full-text analysis evaluating 69 different materials, and 17 studies-still evaluating 36 different materials-were included (3 in situ and 14 in vitro). Ten studies evaluated desensitizers; 8 adhesives; and 1 infiltration. Meta-analyses were possible for all 17 studies. Meta-analyses revealed that lesion depth after no treatment was significantly higher than after the application of single-step adhesives (MD[95%CI] = - 49.82[- 69.34; - 30.30]) and multi-step adhesives (MD[95%CI]=-60.09 [-92.65, -27.54]). No significant differences in the lesion depth increase between single- and multi-step adhesives could be observed (MD[95%CI]=30.13 [-21.14, 81.39]). Furthermore, compared to no treatment the increase of the lesion depth was significantly hampered using desensitizers (MD[95%CI] = - 38.02[- 51.74; - 24.31]). Furthermore, the included studies presented unclear or high risk. A physical diffusion barrier can significantly hamper the increase of lesion depth under cariogenic conditions. Furthermore, multi-step adhesives seem not to be more effective than single-step adhesives. However, this conclusion is based on only few in vitro and in situ studies

Efficacy of nano-hydroxyapatite on caries prevention-a systematic review and meta-analysis.

Introduction/objectives: The review systematically explored in vivo or in situ studies investigating the efficacy of nano-hydroxyapatite (nHA) to reduce initiation of or to remineralize initial caries lesions. Data: Prospective controlled (non-)randomized clinical trials investigating the efficacy of a nHA compared to any other (placebo) treatment or untreated/standard control. Sources: Three electronic databases (Central Cochrane, PubMed-MEDLINE, Ovid EMBASE) were screened. Outcomes were, e.g., ICDAS score, laser fluorescence, enamel remineralization rate, mineral loss, and lesion depth. No language or time restrictions were applied. Risk of bias and level of evidence were graded using the Risk of Bias 2.0 tool and GRADE profiler. Study selection/results: Five in vivo (and 5 in situ) studies with at least 633 teeth (1031 specimens) being assessed in more than 420 (95) patients were included. No meta-analysis could be performed for in vivo studies due to the high heterogeneity of the study designs and the variety of outcomes. In situ studies indicate that under demineralization conditions, NaF was able to hinder demineralization, whereas nHA did not; simultaneously, nHA did not differ from the fluoride-free control. In contrast, under remineralizing conditions, nHA and NaF show the same remineralizing potential. However, the level of evidence was very low. Furthermore, six studies showed a high risk of bias, and six studies were funded/published by the manufacturers of the tested products. Conclusion: The low number of clinical studies, the relatively short follow-up periods, the high risks of bias, and the limiting grade of evidence do not allow for conclusive evidence on the efficacy of nHA. Clinical relevance: No conclusive evidence on the efficacy of nHA could be obtained based on the low number of clinical studies, the relatively short follow-up periods, the high risks of bias, the limiting grade of evidence, and study conditions that do not reflect the everyday conditions

Non-spatial skills differ in the front and rear peri-personal space

In measuring behavioural and pupillary responses to auditory oddball stimuli delivered in the front and rear peri-personal space, we find that pupils dilate in response to rare stimuli, both target and distracters. Dilation in response to targets is stronger than the response to distracters, implying a task relevance effect on pupil responses. Crucially, pupil dilation in response to targets is also selectively modulated by the location of sound sources: stronger in the front than in the rear peri-personal space, in spite of matching behavioural performance. This supports the concept that even non-spatial skills, such as the ability to alert in response to behaviourally relevant events, are differentially engaged across subregions of the peri-personal space

Global radiant flux from active volcanoes: the 2000–2019 MIROVA database

Since 2000, the Moderate Resolution Imaging Spectroradiometer (MODIS) has acquired infrared images of the Earth’s surface daily. These data have made it possible to measure the thermal energy radiated by the world’s most famous volcanoes and also to discover and track eruptions in remote and poorly monitored regions. In this work, we present the database of Volcanic Radiative Power (VRP, in W) time series, recorded by the MIROVA (Middle Infrared Observation of Volcanic Activity) system over 2 decades of MODIS observations (2000–2019) at 111 active volcanoes. The database reveals that globally, the number of thermally active volcanoes each year varies between 60 and 80, almost equally partitioned between volcanoes with a basic (50%) and intermediate (45%) composition, while only 5% is represented by volcanoes erupting acidic lavas. Within the investigated period, the global-scale heat flux was almost stationary, and occasionally punctuated by peaks associated with the largest effusive eruptions (e.g., Bardarbunga and Kilauea). The Volcanic Radiative Energy (VRE, in J) emitted by basic volcanoes (~1.8 × 1018 J) in 20 years constitutes 91% of the total, while intermediates and acids contribute only 8% (~1.8 × 1017 J) and 1% (~1.7 × 1016 J), respectively. A comparison with the volume of lava erupted effusively by the same volcanoes reveals that this difference is attributed to the lower efficiency in radiating thermal energy of increasingly acidic (viscous) lava bodies. Each compositional group is associated with a specific relationship between VRE and erupted volume which characterises most of the effusive volcanoes. On the other hand, some open-vent volcanoes reveal that much more heat is released than that theoretically radiated by the erupted lava. This imbalance (hereby called excess radiation) is attributed to an additional heat source, likely associated with an underlying convective magma column and/or to outgassing through a permeable conduit. We are convinced that the database presented in this work will be useful to support new emerging studies on globalscale volcanism and will contribute to a better understanding of each volcanic system

Development of antigen-specific ELISA for circulating autoantibodies to extracellular matrix protein 1 in lichen sclerosus

Lichen sclerosus is a common, acquired chronic inflammatory skin disease of unknown etiology, although circulating autoantibodies to the glycoprotein extracellular matrix protein 1 (ECM1) have been detected in most patients’ sera. We have examined the nature of ECM1 epitopes in lichen sclerosus sera, developed an ELISA system for serologic diagnosis, and assessed clinicopathological correlation between ELISA titer and disease. Epitope-mapping studies revealed that lichen sclerosus sera most frequently recognized the distal second tandem repeat domain and carboxyl-terminus of ECM1. We analyzed serum autoantibody reactivity against this immunodominant epitope in 413 individuals (95 subjects with lichen sclerosus, 161 normal control subjects, and 157 subjects with other autoimmune basement membrane or sclerosing diseases). The ELISA assay was highly sensitive; 76 of 95 lichen sclerosus patients (80.0%) exhibited IgG reactivity. It was also highly specific (93.7%) in discriminating between lichen sclerosus and other disease/control sera. Higher anti-ECM1 titers also correlated with more longstanding and refractory disease and cases complicated by squamous cell carcinoma. Furthermore, passive transfer of affinity-purified patient IgG reproduced some histologic and immunopathologic features of lichen sclerosus skin. This new ELISA is valuable for the accurate detection and quantification of anti-ECM1 autoantibodies. Moreover, the values may have clinical significance in patients with lichen sclerosus

Evaluation of different peach genotypes for resistance to Plum pox virus

Different responses to the experimental inoculation with a PPV-M isolate were observed in peach germplasm derived from crosses between Prunus persica and peach related species showing resistance to several pathogens. The response evaluation was performed by correlating the phenotypic analysis with serological and molecular tests. Twenty-one individuals, asymptomatic and with low concentration of the virus inside the leaf tissues, have been selected. This germplasm can be considered ‘highly tolerant’ or ‘resistant’ and must be submitted to further investigations.Keywords: PPV, Prunus persica, P. davidiana, P. ferganensis, toleranc

Screening of suitable cationic dopants for solar absorber material CZTS/Se: A first principles study

The earth abundant and non-toxic solar absorber material kesterite Cu2ZnSn(S/Se)(4) has been studied to achieve high power conversion efficiency beyond various limitations, such as secondary phases, antisite defects, band gap adjustment and microstructure. To alleviate these hurdles, we employed screening based approach to find suitable cationic dopant that can promote the current density and the theoretical maximum upper limit of the energy conversion efficiency (P(%)) of CZTS/Se solar devices. For this task, the hybrid functional (Heyd, Scuseria and Ernzerhof, HSE06) were used to study the electronic and optical properties of cation (Al, Sb, Ga, Ba) doped CZTS/Se. Our in-depth investigation reveals that the Sb atom is suitable dopant of CZTS/CZTSe and also it has comparable bulk modulus as of pure material. The optical absorption coefficient of Sb doped CZTS/Se is considerably larger than the pure materials because of easy formation of visible range exciton due to the presence of defect state below the Fermi level, which leads to an increase in the current density and P(%). Our results demonstrate that the lower formation energy, preferable energy gap and excellent optical absorption of the Sb doped CZTS/Se make it potential component for relatively high efficient solar cells

Hypnosis and Sedation for Anxious Children Undergoing Dental Treatment: A Retrospective Practice-Based Longitudinal Study.

To assess whether the treatment of children with oral midazolam and pediatric hypnosis techniques can improve the compliance in consecutive sessions, a retrospective longitudinal practice-based observational study was designed and carried out. A total of 311 children between 3 and 12 years of age were treated under hypnosis and sedation with midazolam (0.40 mg/kg body weight). Treatments were performed in one to a maximum of three sessions. A total of 183 children received one, 103 received two and 25 children received three treatment sessions. The behavior of the children during the sessions was examined by means of the Venham score. The self-evaluation of the children was based on the Wong-Baker Scale. Child behavior using midazolam and hypnosis techniques showed little difference and good compliance between the sessions. Venham scores did not increase significantly regarding total treatment from the first (0.99 ± 1.41) to the second (1.17 ± 1.39) and to the third session (1.27 ± 1.20) (p > 0.05). However, considering the highest Venham scores that occurred in each case, the behavior of the children worsened significantly (p < 0.01) during the three treatment sessions, from 1.37 ± 1.31 (first) to 1.87 ± 1.74 (second) to 2.32 ± 1.33 (third). In 6.11% of the children, treatment was discontinued in the first session (n = 19), 0.96% in the second (n = 3) and 0% in the third. Treatment with low-dose midazolam, combined with hypnosis techniques, showed to be an effective option for dental treatment in children. Within the limitations of the current study, and with consideration of highest possible compliance, no more than two treatment sessions for pediatric dental treatment should be performed