Correlación entre el suministro de extracto de ajo en pollos Broiler como promotor de crecimiento

En los sistemas de producción avícola, la alimentación e incorporación de aditivos y/o suplementos juega un papel importante en el desarrollo de los animales, también en el rendimiento económico productivo. Se pretende realizar la comparación en ganancia de peso diario (GPD), costos de producción (CP), palatabilidad de canal (PC), rendimientos de carne en ala, pierna y pernil en de los pollos Broiler de engorde, el estudio tuvo un periodo de 40 días, con el fin de evaluar los efectos del uso de sustancias como fuentes precursoras de ganancia de peso y crecimiento de las aves. Para el desarrollo del estudio se realizó una distribución y selección de dos grupos homogéneos conformados por 10 animales o réplicas, de 3 días de edad. A cada grupo de animales se le asignó un tratamiento, el tratamiento control consistió en el suministro convencional de concentrado comercial para pollos de engorde marca Contegral según recomendaciones de la casa incubadora de donde proviene los animales, el segundo tratamiento se agregó el concentrado y el extracto de ajo en proporción al 2%. Para la cuantificación de las variables y análisis estadístico de los resultados se utilizó un diseño estadístico completamente al azar apoyados en el Spss20 mediante las pruebas de Dunkan, Tukey y chi cuadrado.In poultry production systems, feeding and incorporation of additives and / or supplements plays an important role in the development of animals, also in the productive economic performance. Pretending to achieve the comparisón in weight gain diary (GPD), production cost (CP), channel palatability (PC), meat yields in wing, leg and pernil in broiler chickens for fattening, the study had a period of 40 days, with I have finely evaluated the successful outcome of the plenary's pre-eminence and growth of birds. For the development of the study a distribution and selection of two homogeneous groups was made conformed by 10 animals or replicas of 3 days of age. To drop the group of animals assigned a treatment, the control treatment consisted of the conventional supply of The commercial concentration of the trade mark Context according to recommendations of the house incubator where the animals come from, the second treatment was added concentrate in an extract of less than 2%. For the quantification of the variables and statistical analysis of the results used a design statistic completely randomly supported in the Spss20 by the Dunkan tests, Tukey and chi square

Global variation in postoperative mortality and complications after cancer surgery: a multicentre, prospective cohort study in 82 countries

© 2021 The Author(s). Published by Elsevier Ltd. This is an Open Access article under the CC BY-NC-ND 4.0 licenseBackground: 80% of individuals with cancer will require a surgical procedure, yet little comparative data exist on early outcomes in low-income and middle-income countries (LMICs). We compared postoperative outcomes in breast, colorectal, and gastric cancer surgery in hospitals worldwide, focusing on the effect of disease stage and complications on postoperative mortality. Methods: This was a multicentre, international prospective cohort study of consecutive adult patients undergoing surgery for primary breast, colorectal, or gastric cancer requiring a skin incision done under general or neuraxial anaesthesia. The primary outcome was death or major complication within 30 days of surgery. Multilevel logistic regression determined relationships within three-level nested models of patients within hospitals and countries. Hospital-level infrastructure effects were explored with three-way mediation analyses. This study was registered with ClinicalTrials.gov, NCT03471494. Findings: Between April 1, 2018, and Jan 31, 2019, we enrolled 15 958 patients from 428 hospitals in 82 countries (high income 9106 patients, 31 countries; upper-middle income 2721 patients, 23 countries; or lower-middle income 4131 patients, 28 countries). Patients in LMICs presented with more advanced disease compared with patients in high-income countries. 30-day mortality was higher for gastric cancer in low-income or lower-middle-income countries (adjusted odds ratio 3·72, 95% CI 1·70–8·16) and for colorectal cancer in low-income or lower-middle-income countries (4·59, 2·39–8·80) and upper-middle-income countries (2·06, 1·11–3·83). No difference in 30-day mortality was seen in breast cancer. The proportion of patients who died after a major complication was greatest in low-income or lower-middle-income countries (6·15, 3·26–11·59) and upper-middle-income countries (3·89, 2·08–7·29). Postoperative death after complications was partly explained by patient factors (60%) and partly by hospital or country (40%). The absence of consistently available postoperative care facilities was associated with seven to 10 more deaths per 100 major complications in LMICs. Cancer stage alone explained little of the early variation in mortality or postoperative complications. Interpretation: Higher levels of mortality after cancer surgery in LMICs was not fully explained by later presentation of disease. The capacity to rescue patients from surgical complications is a tangible opportunity for meaningful intervention. Early death after cancer surgery might be reduced by policies focusing on strengthening perioperative care systems to detect and intervene in common complications. Funding: National Institute for Health Research Global Health Research Unit

Effects of hospital facilities on patient outcomes after cancer surgery: an international, prospective, observational study

© 2022 The Author(s). Published by Elsevier Ltd. This is an Open Access article under the CC BY 4.0 licenseBackground: Early death after cancer surgery is higher in low-income and middle-income countries (LMICs) compared with in high-income countries, yet the impact of facility characteristics on early postoperative outcomes is unknown. The aim of this study was to examine the association between hospital infrastructure, resource availability, and processes on early outcomes after cancer surgery worldwide. Methods: A multimethods analysis was performed as part of the GlobalSurg 3 study—a multicentre, international, prospective cohort study of patients who had surgery for breast, colorectal, or gastric cancer. The primary outcomes were 30-day mortality and 30-day major complication rates. Potentially beneficial hospital facilities were identified by variable selection to select those associated with 30-day mortality. Adjusted outcomes were determined using generalised estimating equations to account for patient characteristics and country-income group, with population stratification by hospital. Findings: Between April 1, 2018, and April 23, 2019, facility-level data were collected for 9685 patients across 238 hospitals in 66 countries (91 hospitals in 20 high-income countries; 57 hospitals in 19 upper-middle-income countries; and 90 hospitals in 27 low-income to lower-middle-income countries). The availability of five hospital facilities was inversely associated with mortality: ultrasound, CT scanner, critical care unit, opioid analgesia, and oncologist. After adjustment for case-mix and country income group, hospitals with three or fewer of these facilities (62 hospitals, 1294 patients) had higher mortality compared with those with four or five (adjusted odds ratio [OR] 3·85 [95% CI 2·58–5·75]; p<0·0001), with excess mortality predominantly explained by a limited capacity to rescue following the development of major complications (63·0% vs 82·7%; OR 0·35 [0·23–0·53]; p<0·0001). Across LMICs, improvements in hospital facilities would prevent one to three deaths for every 100 patients undergoing surgery for cancer. Interpretation: Hospitals with higher levels of infrastructure and resources have better outcomes after cancer surgery, independent of country income. Without urgent strengthening of hospital infrastructure and resources, the reductions in cancer-associated mortality associated with improved access will not be realised. Funding: National Institute for Health and Care Research