627 research outputs found
A Multi Megawatt Cyclotron Complex to Search for CP Violation in the Neutrino Sector
A Multi Megawatt Cyclotron complex able to accelerate H2+ to 800 MeV/amu is
under study. It consists of an injector cyclotron able to accelerate the
injected beam up to 50 MeV/n and of a booster ring made of 8 magnetic sectors
and 8 RF cavities. The magnetic field and the forces on the superconducting
coils are evaluated using the 3-D code OPERA. The injection and extraction
trajectories are evaluated using the well tested codes developed by the MSU
group in the '80s. The advantages to accelerate H2+ are described and
preliminary evaluations on the feasibility and expected problems to build the
injector cyclotron and the ring booster are here presented.Comment: Presentation at Cyclotron'10 conference, Lanzhou, China, Sept 7, 201
Design of the RF system for a 250 A.MeV superconducting cyclotron
International audienceA superconducting cyclotron accelerating q/A=0.5 ions up to 250 A.MeV, for medical applications and radioisotopes production (SCENT project) is being studied at Laboratori Nazionali del Sud in Catania. The RF system, working in the fourth harmonic, is based on four cavities operating at 93 MHz, which are connected in the central region. The paper describes an unusual multistem RF design, performed with 3D electromagnetic codes. The aim is to obtain a cavity, completely housed in the valley, with a voltage distribution going from 65 kV in the injection region to a peak value of 120 kV in the extraction region, and a low power consumption
Representations of Time Coordinates in FITS
In a series of three previous papers, formulation and specifics of the
representation of World Coordinate Transformations in FITS data have been
presented. This fourth paper deals with encoding time. Time on all scales and
precisions known in astronomical datasets is to be described in an unambiguous,
complete, and self-consistent manner. Employing the well--established World
Coordinate System (WCS) framework, and maintaining compatibility with the FITS
conventions that are currently in use to specify time, the standard is extended
to describe rigorously the time coordinate. World coordinate functions are
defined for temporal axes sampled linearly and as specified by a lookup table.
The resulting standard is consistent with the existing FITS WCS standards and
specifies a metadata set that achieves the aims enunciated above.Comment: FITS WCS Paper IV: Time. 27 pages, 11 table
Finite element analysis of horizontal axis wind turbines performance
This paper presents an aeroelastic formulation based on the Finite Element Method
(FEM) to predict the performance of an isolated horizontal axis wind turbine.
Hamiltonâs principle is applied to derive the equations of blade(s) aeroelasticity, based
on a nonlinear beam model coupled with Beddoes-Leishman unsteady sectional aerodynamics.
A devoted fifteen-degrees of freedom finite element, able to accurately model the kinematics and
elastic behavior of rotating blades, is introduced and the spatial discretization of the
aeroelastic equations is carried-out yielding a set of coupled nonlinear ordinary differential
equations that are then solved by a time-marching algorithm. The proposed formulation may be
enhanced to face the analysis of advanced blade shapes, including the presence of the
tower, and represents the first step of an ongoing activity on wind energy based on a FEM
approach. Due to similarities between wind turbine and helicopter rotor blades
aeroelasticity, validation results firstly concern with the aeroelastic response of a helicopter
rotor in hovering. Next, the performance of a wind turbine in terms of blade elastic
response and delivered power are
predicted and compared with available literature data
Finite element analysis of horizontal axis wind turbines performance
This paper presents an aeroelastic formulation based on the Finite Element Method
(FEM) to predict the performance of an isolated horizontal axis wind turbine.
Hamiltonâs principle is applied to derive the equations of blade(s) aeroelasticity, based
on a nonlinear beam model coupled with Beddoes-Leishman unsteady sectional aerodynamics.
A devoted fifteen-degrees of freedom finite element, able to accurately model the kinematics and
elastic behavior of rotating blades, is introduced and the spatial discretization of the
aeroelastic equations is carried-out yielding a set of coupled nonlinear ordinary differential
equations that are then solved by a time-marching algorithm. The proposed formulation may be
enhanced to face the analysis of advanced blade shapes, including the presence of the
tower, and represents the first step of an ongoing activity on wind energy based on a FEM
approach. Due to similarities between wind turbine and helicopter rotor blades
aeroelasticity, validation results firstly concern with the aeroelastic response of a helicopter
rotor in hovering. Next, the performance of a wind turbine in terms of blade elastic
response and delivered power are
predicted and compared with available literature data
Anomalous radio emission from dust in the Helix
A byproduct of experiments designed to map the CMB is the recent detection of
a new component of foreground Galactic emission. The anomalous foreground at ~
10--30 GHz, unexplained by traditional emission mechanisms, correlates with
100um dust emission. We report that in the Helix the emission at 31 GHz and
100um are well correlated, and exhibit similar features on sky images, which
are absent in H\beta. Upper limits on the 250 GHz continuum emission in the
Helix rule out cold grains as candidates for the 31 GHz emission, and provide
spectroscopic evidence for an excess at 31 GHz over bremsstrahlung. We estimate
that the 100um-correlated radio emission, presumably due to dust, accounts for
at least 20% of the 31 GHz emission in the Helix. This result strengthens
previous tentative interpretations of diffuse ISM spectra involving a new dust
emission mechanism at radio frequencies. Very small grains have not been
detected in the Helix, which hampers interpreting the new component in terms of
spinning dust. The observed iron depletion in the Helix favors considering the
identity of this new component to be magnetic dipole emission from hot
ferromagnetic grains. The reduced level of free-free continuum we report also
implies an electronic temperature of Te=4600\pm1200K for the free-free emitting
material, which is significantly lower than the temperature of 9500\pm500K
inferred from collisionally-excited lines (abridged).Comment: Accepted for publication in Ap
The antibody-drug conjugate loncastuximab tesirine for the treatment of diffuse large B-cell lymphoma
Diffuse large B-cell lymphoma (DLBCL) is a heterogenous subtype of non-Hodgkin lymphoma. Relapsed/refractory disease represents remains an unmet medical need, despite the introduction of novel cellular and targeted therapies. Loncastuximab tesirine is a cluster of differentiation19-targeting antibody-drug conjugate approved by the US Food and Drug Administration for relapsed DLBCL after 2 lines of systemic therapy based on a trial showing a 48.3% overall response rate. The spectrum of its clinical applications is expanding and is now being tested in other B-cell malignancies
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