1,298 research outputs found
Carbon Emission Trading Scheme and the Aviation Sector: An experimental analysis on allocation of allowances
The European Union has proposed a Directive to include aviation activities in the Emission Trading Scheme (ETS) in 2012. The allowance allocation method which will be put in place is relatively easy to implement with low administration cost. However, careful scrutiny suggests that the allocation method does not favor airlines with high energy efficiency. This study proposes an alternative allowance allocation method which is fairer in that it rewards energy efficient airlines. Further, the new method is easy to implement with low administrative cost. The Cournot model serves as the theoretical foundation upon which the experiments are designed to simulate the aviation industry under the ETS. The equilibrium is calculated for each allowance allocation method. Results from experiments suggest consistency with theoretical outcomes.
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Schwannomatosis of the Spinal Accessory Nerve: A Case Report.
Schwannomatosis is a distinct syndrome characterized by multiple peripheral nerve schwannomas that can be sporadic or familial in nature. Cases affecting the lower cranial nerves are infrequent. Here, the authors present a rare case of schwannomatosis affecting the left spinal accessory nerve. Upon genetic screening, an in-frame insertion at codon p.R177 of the Sox 10 gene was observed. There were no identifiable alterations in NF1, NF2, LZTR1, and SMARCB1. This case demonstrates a rare clinical presentation of schwannomatosis in addition to a genetic aberration that has not been previously reported in this disease context
Rho-associated kinase signalling and the cancer microenvironment: novel biological implications and therapeutic opportunities
The Rho/ROCK pathway is involved in numerous pivotal cellular processes that have made it an area of intense study in cancer medicine, however, Rho-associated coiled-coil containing protein kinase (ROCK) inhibitors are yet to make an appearance in the clinical cancer setting. Their performance as an anti-cancer therapy has been varied in pre-clinical studies, however, they have been shown to be effective vasodilators in the treatment of hypertension and post-ischaemic stroke vasospasm. This review addresses the various roles the Rho/ROCK pathway plays in angiogenesis, tumour vascular tone and reciprocal feedback from the tumour microenvironment and explores the potential utility of ROCK inhibitors as effective vascular normalising agents. ROCK inhibitors may potentially enhance the delivery and efficacy of chemotherapy agents and improve the effectiveness of radiotherapy. As such, repurposing of these agents as adjuncts to standard treatments may significantly improve outcomes for patients with cancer. A deeper understanding of the controlled and dynamic regulation of the key components of the Rho pathway may lead to effective use of the Rho/ROCK inhibitors in the clinical management of cancer
Cellulase production by the Thermophilic Fungus, Thermoascus aurantiacus
Thermoascus aurantiacus was the most active cellulase producer of several thermphilic fungi tested.
The optimum growth temperature for T. aurantiacus in liquid medium was 45° C and maximum cellulase
production from filter paper occurred at 40°C. The optimum temperatue for {3-glucosidase and carboxymethylcellulase
activity was 70° C; for filter paper degrading activity it was 65°C. Maximum activity was
found at pH 5.0 for the filter paper degrading enzyme and glucosidase and pH 4.3 for carboxymethylcellulase
activity
Analysis of Cost at FAA’s En Route Centers: An Empirical Perspective
In this paper, an empirical framework is developed using economic theories to examine the relationships between variable costs and levels of activities at the Federal Aviation Administration's (FAA) en route centers. Using data for three fiscal years and employing time-series pooled cross section econometrics, we have found that the Air Traffic Organization's (ATO) service provisions in the en route centers have some economies of scale. Furthermore, we have found that while controllers' wage is important, it is not statistically significant in unit cost measured in aircraft flight operation counts. However, it is statistically significant when unit variable cost is measured and estimated in terms of aircraft flight operation hours. We have also found that degree of complexity, a measure of service attributes, does not impact cost. These findings, combined with on-going policy discussion on users' fees, imply that ATO may be well positioned to implement average cost pricing if cost is to be fully recovered for en route services. The implementation of marginal cost pricing may require external funding, perhaps from general funds of the U.S. Treasury
Analysis of Cost at FAA’s En Route Centers: An Empirical Perspective
In this paper, an empirical framework is developed using economic theories to examine the relationships between variable costs and levels of activities at the Federal Aviation Administration's (FAA) en route centers. Using data for three fiscal years and employing time-series pooled cross section econometrics, we have found that the Air Traffic Organization's (ATO) service provisions in the en route centers have some economies of scale. Furthermore, we have found that while controllers' wage is important, it is not statistically significant in unit cost measured in aircraft flight operation counts. However, it is statistically significant when unit variable cost is measured and estimated in terms of aircraft flight operation hours. We have also found that degree of complexity, a measure of service attributes, does not impact cost. These findings, combined with on-going policy discussion on users' fees, imply that ATO may be well positioned to implement average cost pricing if cost is to be fully recovered for en route services. The implementation of marginal cost pricing may require external funding, perhaps from general funds of the U.S. Treasury
Techno-economic assessment of offshore wind-to-hydrogen scenarios: A UK case study
The installed capacity, electricity generation from wind, and the curtailment of wind power in the UK between 2011 and 2021 showed that penetration levels of wind energy and the amount of energy that is curtailed in future would continue to rise whereas the curtailed energy could be utilised to produce green hydrogen. In this study, data were collected, technologies were chosen, systems were designed, and simulation models were developed to determine technical requirements and levelised costs of hydrogen produced and transported through different pathways. The analysis of capital and operating costs of the main components used for onshore and offshore green hydrogen production using offshore wind, including alternative strategies for hydrogen storage and transport and hydrogen carriers, showed that a significant reduction in cost could be achieved by 2030, enabling the production of green hydrogen from offshore wind at a competitive cost compared to grey and blue hydrogen. Among all scenarios investigated in this study, compressed hydrogen produced offshore is the most cost-effective scenario for projects starting in 2025, although the economic feasibility of this scenario is strongly affected by the storage period and the distance to the shore of the offshore wind farm. Alternative scenarios for hydrogen storage and transport, such as liquefied hydrogen and methylcyclohexane, could become more cost-effective for projects starting in 2050, when the levelised cost of hydrogen could reach values of about £2 per kilogram of hydrogen or lower
First Detection of A Linear Structure in the Midplane of the Young HH 211 Protostellar Disk: A Spiral Arm?
Spiral structures have been detected in evolved protostellar disks, driving
the disk accretion towards the central protostars to facilitate star formation.
However, it is still unclear if these structures can form earlier in young
protostellar disks. With the Atacama Large Millimeter/submillimeter Array
(ALMA), we have detected and spatially resolved a very young and nearly edge-on
dusty disk with a radius of only ~ 20 au in the HH 211 protostellar system at
submillimeter wavelength. It is geometrically thick, indicating that the
submillimeter light-emitting dust grains have yet to settle to the midplane for
planet formation. Intriguingly, it shows 3 bright linear structures parallel to
the equatorial plane, resembling a 3-layer pancake that has not been seen
before. The top and bottom ones arise from the warm disk surfaces, unveiling
the flared structure of the disk. More importantly, the middle one is in the
dense midplane of the disk and can be modeled as a trailing spiral arm excited
by disk gravity, as seen in evolved protostellar disks, supporting the presence
of spiral structures in the very early phase for disk accretion.Comment: 19 pages, 4 figure
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