12,263 research outputs found
Views of the first cohort of HKU notebook programme participants
In 1998, the University of Hong Kong was the first tertiary institution in Asia to implement a campuswide notebook computer programme, where each incoming student is enabled to own a personal notebook computer. At the beginning of each year, incoming students are surveyed to collect baseline data about their self-reported computer skills and their attitudes about computer use in education. In mid-May 2001, at the end of their undergraduate education, the 1998 cohort was surveyed again to gauge the changes, if any, in the skills and attitudes of the students after three years of study at the university and to collect the opinions of the students for future directives concerning IT in education at the University. Generally, students who participated in the notebook programme were satisfied and found the ThinkPads to be useful in their coursework and studies, using them for about 14 hours a week for school work.published_or_final_versio
Chirality in the plane
It is well-known that many three-dimensional chiral material models become non-chiral when reduced to two dimensions. Chiral properties of the two-dimensional model can then be restored by adding appropriate two-dimensional chiral terms. In this paper we show how to construct a three-dimensional chiral energy function which can achieve two-dimensional chirality induced already by a chiral three-dimensional model. The key ingredient to this approach is the consideration of a nonlinear chiral energy containing only rotational parts. After formulating an appropriate energy functional, we study the equations of motion and find explicit soliton solutions displaying two-dimensional chiral properties
Effect of microstructural evolution on magnetic property of Mn-implanted p-type GaN
The effect of microstructural evolution on magnetic property of Mn-implanted p-type GaN was discussed. The effect was studied using cross-sectional transmission electron microscopy (TEM). It was shown that the higher-temperature annealing reduced the ferromagnetic signal and produced antiferromagnetic Mn-nitride nanoclusters.open161
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Dentate granule cells form novel basal dendrites in a rat model of temporal lobe epilepsy.
Mossy fibre sprouting and re-organization in the inner molecular layer of the dentate gyrus is a characteristic of many models of temporal lobe epilepsy including that induced by perforant-path stimulation. However, neuroplastic changes on the dendrites of granule cells have been less-well studied. Basal dendrites are a transient morphological feature of rodent granule cells during development. The goal of the present study was to examine whether granule cell basal dendrites are generated in rats with epilepsy induced by perforant-path stimulation. Adult Wistar rats were stimulated for 24 h at 2 Hz and with intermittent (1/min) trains (10 s duration) of single stimuli at 20 Hz (20 V, 0.1 ms) delivered 1/min via an electrode placed in the angular bundle. The brains of these experimental rats and age- and litter-matched control animals were processed for the rapid Golgi method. All rats with perforant-path stimulation displayed basal dendrites on many Golgi-impregnated granule cells. These basal dendrites mainly originated from their somata at the hilar side and then extended into the hilus. Quantitative analysis of more than 800 granule cells in the experimental and matched control brains showed that 6-15% (mean=8.7%) of the impregnated granule cells have spiny basal dendrites on the stimulated side, as well as the contralateral side (mean=3.1%, range=2.9-3.9%) of experimental rats, whereas no basal dendrites were observed in the dentate gyrus from control animals. The formation of basal dendrites appears to be an adaptive morphological change for granule cells in addition to the previously described mossy fibre sprouting, as well as dendritic and somatic spine formation observed in the dentate gyrus of animal and human epileptic brains. The presence of these dendrites in the subgranular region of the hilus suggests that they may be postsynaptic targets of the mossy fibre collaterals
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Adipocyte PU.1 knockout promotes insulin sensitivity in HFD-fed obese mice.
Insulin resistance is a key feature of obesity and type 2 diabetes. PU.1 is a master transcription factor predominantly expressed in macrophages but after HFD feeding PU.1 expression is also significantly increased in adipocytes. We generated adipocyte specific PU.1 knockout mice using adiponectin cre to investigate the role of PU.1 in adipocyte biology, insulin and glucose homeostasis. In HFD-fed obese mice systemic glucose tolerance and insulin sensitivity were improved in PU.1 AKO mice and clamp studies indicated improvements in both adipose and liver insulin sensitivity. At the level of adipose tissue, macrophage infiltration and inflammation was decreased and glucose uptake was increased in PU.1 AKO mice compared with controls. While PU.1 deletion in adipocytes did not affect the gene expression of PPARg itself, we observed increased expression of PPARg target genes in eWAT from HFD fed PU.1 AKO mice compared with controls. Furthermore, we observed decreased phosphorylation at serine 273 in PU.1 AKO mice compared with fl/fl controls, indicating that PPARg is more active when PU.1 expression is reduced in adipocytes. Therefore, in obesity the increased expression of PU.1 in adipocytes modifies the adipocyte PPARg cistrome resulting in impaired glucose tolerance and insulin sensitivity
Atomic Layer Deposition of Ni Thin Films and Application to Area-Selective Deposition
Ni thin films were deposited by atomic layer deposition (ALD) using bis(dimethylamino-2-methyl-2-butoxo)nickel [Ni(dmamb)(2)] as a precursor and NH3 gas as a reactant. The growth characteristics and film properties of ALD Ni were investigated. Low-resistivity films were deposited on Si and SiO2 substrates, producing high-purity Ni films with a small amount of oxygen and negligible amounts of nitrogen and carbon. Additionally, ALD Ni showed excellent conformality in nanoscale via holes. Utilizing this conformality, Ni/Si core/shell nanowires with uniform diameters were fabricated. By combining ALD Ni with octadecyltrichlorosilane (OTS) self-assembled monolayer as a blocking layer, area-selective ALD was conducted for selective deposition of Ni films. When performed on the prepatterned OTS substrate, the Ni films were selectively coated only on OTS-free regions, building up Ni line patterns with 3 mu m width. Electrical measurement results showed that all of the Ni lines were electrically isolated, also indicating the selective Ni deposition. (C) 2010 The Electrochemical Society. [DOI: 10.1149/1.3504196] All rights reserved.ope
Interactions of C+(2PJ) with rare gas atoms: incipient chemical interactions, potentials and transport coefficients
Accurate interatomic potentials were calculated for the interaction of a singly charged carbon cation, C+, with a single rare gas atom, RG (RG = Ne–Xe). The RCCSD(T) method and basis sets of quadruple-ζ and quintuple-ζ quality were employed; each interaction energy was counterpoise corrected and extrapolated to the basis set limit. The lowest C+(2P) electronic term of the carbon cation was considered, and the interatomic potentials calculated for the diatomic terms that arise from these: 2Π and 2Σ+. Additionally, the interatomic potentials for the respective spin-orbit levels were calculated, and the effect on the spectroscopic parameters was examined. In doing this, anomalously large spin-orbit splittings for RG = Ar–Xe were found, and this was investigated using multi-reference configuration interaction calculations. The latter indicated a small amount of RG → C+ electron transfer and this was used to rationalize the observations. This is taken as evidence of an incipient chemical interaction, which was also examined via contour plots, Birge–Sponer plots and various population analyses across the C+-RG series (RG = He–Xe), with the latter showing unexpected results. Trends in several spectroscopic parameters were examined as a function of the increasing atomic number of the RG atom. Finally, each set of RCCSD(T) potentials was employed, including spin-orbit coupling to calculate the transport coefficients for C+ in RG, and the results were compared with the limited available data
Dilemmas in doing insider research in professional education
This article explores the dilemmas I encountered when researching social work education in England as an insider researcher who was simultaneously employed as an educator in the host institution. This was an ethnographic project deploying multiple methods and generating rich case study material which informed the student textbook Becoming a Social Worker the four-year period of the project. First, ethical dilemmas emerged around informed consent and confidentiality when conducting surveys of students and reading their portfolios. Second, professional dilemmas stemmed from the ways in which my roles as a researcher, academic tutor, social worker and former practice educator converged and collided. Third, political dilemmas pertained to the potential for the project to crystallize and convey conflicts among stakeholders in the university and community. Since the majority of research in social work education is conducted by insiders, we have a vital interest in making sense of such complexity
Higher-order scalar interactions and SM vacuum stability
Investigation of the structure of the Standard Model effective potential at
very large field strengths opens a window towards new phenomena and can reveal
properties of the UV completion of the SM. The map of the lifetimes of the
vacua of the SM enhanced by nonrenormalizable scalar couplings has been
compiled to show how new interactions modify stability of the electroweak
vacuum. Whereas it is possible to stabilize the SM by adding Planck scale
suppressed interactions and taking into account running of the new couplings,
the generic effect is shortening the lifetime and hence further destabilisation
of the SM electroweak vacuum. These findings have been illustrated with phase
diagrams of modified SM-like models. It has been demonstrated that
stabilisation can be achieved by lowering the suppression scale of higher order
operators while picking up such combinations of new couplings, which do not
deepen the new minima of the potential. Our results show the dependence of the
lifetime of the electroweak minimum on the magnitude of the new couplings,
including cases with very small couplings (which means very large effective
suppression scale) and couplings vastly different in magnitude (which
corresponds to two different suppression scales).Comment: plain Latex, 9 figure
Soliton solutions in geometrically nonlinear Cosserat micropolar elasticity with large deformations
We study the fully nonlinear dynamical Cosserat micropolar elasticity problem in three dimensions with various energy functionals dependent on the microrotation [Formula presented] and the deformation gradient tensor [Formula presented]. We derive a set of coupled nonlinear equations of motion from first principles by varying the complete energy functional. We obtain a double sine–Gordon equation and construct soliton solutions. We show how the solutions can determine the overall deformational behaviours and discuss the relations between wave numbers and wave velocities thereby identifying parameter values where the soliton solution does not exist
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