The market for insulation in Alaska and feasibility of the regional manufacture of insulating materials

This investigation was undertaken jointly by the Mineral Industry Research Laboratory and the Institute of Business, Economic and Government Research at the University of Alaska. It is one of a continuing series of studies concerning the market and utilization rate for selected structural materials within Alaska. The overall objective of these studies is to identify opportunities for the regional manufacture of selected building products. In this manner, this limited study of insulation markets complements more extensive previous studies concerning Alaskan cement and clay products, markets and manufacturing feasibility

The Generalized Green-Schwarz Mechanism for Type IIB Orientifolds with D3- and D7-Branes

In this paper, we work out in detail the tadpole cancellation conditions as well as the generalized Green-Schwarz mechanism for type IIB orientifold compactifications with D3- and D7-branes. We find that not only the well-known D3- and D7-tadpole conditions have to be satisfied, but in general also the vanishing of the induced D5-brane charges leads to a non-trivial constraint. In fact, for the case $h^{1,1}_{-} \neq 0$ the latter condition is important for the cancellation of chiral anomalies. We also extend our analysis by including D9- as well as D5-branes and determine the rules for computing the chiral spectrum of the combined system.Comment: 33+7 pages; 2 figures; v2: references added; v3: published versio

Intoxicação por monofluoroacetato em animais

O monofluoroacetato (MF) ou ácido monofluoroacético é utilizado na Austrália e Nova Zelândia no controle populacional de mamíferos nativos ou exóticos. O uso desse composto é proibido no Brasil, devido ao risco de intoxicação de seres humanos e de animais, uma vez que a substância permanece estável por décadas. No Brasil casos recentes de intoxicação criminosa ou acidental têm sido registrados. MF foi identificado em diversas plantas tóxicas, cuja ingestão determina "morte súbita"; de bovinos na África do Sul, Austrália e no Brasil. O modo de ação dessa substância baseia-se na formação do fluorocitrato, seu metabólito ativo, que bloqueia competitivamente a aconitase e o ciclo de Krebs, o que reduz produção de ATP. As espécies animais têm sido classificadas nas quatro Categorias em função do efeito provocado por MF: (I) no coração, (II) no sistema nervoso central (III) sobre o coração e sistema nervoso central ou (IV) com sintomatologia atípica. Neste trabalho, apresenta-se uma revisão crítica atualizada sobre essa substância. O diagnóstico da intoxicação por MF é realizado pelo histórico de ingestão do tóxico, pelos achados clínicos e confirmado por exame toxicológico. Uma forma peculiar de degeneração hidrópico-vacuolar das células epiteliais dos túbulos uriníferos contorcidos distais tem sido considerada como característica dessa intoxicação em algumas espécies. O tratamento da intoxicação por MF é um desafio, pois ainda não se conhece um agente capaz de reverte-la de maneira eficaz; o desfecho geralmente é fata

The Cholecystectomy As A Day Case (CAAD) Score: A Validated Score of Preoperative Predictors of Successful Day-Case Cholecystectomy Using the CholeS Data Set

Background Day-case surgery is associated with significant patient and cost benefits. However, only 43% of cholecystectomy patients are discharged home the same day. One hypothesis is day-case cholecystectomy rates, defined as patients discharged the same day as their operation, may be improved by better assessment of patients using standard preoperative variables. Methods Data were extracted from a prospectively collected data set of cholecystectomy patients from 166 UK and Irish hospitals (CholeS). Cholecystectomies performed as elective procedures were divided into main (75%) and validation (25%) data sets. Preoperative predictors were identified, and a risk score of failed day case was devised using multivariate logistic regression. Receiver operating curve analysis was used to validate the score in the validation data set. Results Of the 7426 elective cholecystectomies performed, 49% of these were discharged home the same day. Same-day discharge following cholecystectomy was less likely with older patients (OR 0.18, 95% CI 0.15–0.23), higher ASA scores (OR 0.19, 95% CI 0.15–0.23), complicated cholelithiasis (OR 0.38, 95% CI 0.31 to 0.48), male gender (OR 0.66, 95% CI 0.58–0.74), previous acute gallstone-related admissions (OR 0.54, 95% CI 0.48–0.60) and preoperative endoscopic intervention (OR 0.40, 95% CI 0.34–0.47). The CAAD score was developed using these variables. When applied to the validation subgroup, a CAAD score of ≤5 was associated with 80.8% successful day-case cholecystectomy compared with 19.2% associated with a CAAD score >5 (p < 0.001). Conclusions The CAAD score which utilises data readily available from clinic letters and electronic sources can predict same-day discharges following cholecystectomy

Reducing the environmental impact of surgery on a global scale: systematic review and co-prioritization with healthcare workers in 132 countries

Background Healthcare cannot achieve net-zero carbon without addressing operating theatres. The aim of this study was to prioritize feasible interventions to reduce the environmental impact of operating theatres. Methods This study adopted a four-phase Delphi consensus co-prioritization methodology. In phase 1, a systematic review of published interventions and global consultation of perioperative healthcare professionals were used to longlist interventions. In phase 2, iterative thematic analysis consolidated comparable interventions into a shortlist. In phase 3, the shortlist was co-prioritized based on patient and clinician views on acceptability, feasibility, and safety. In phase 4, ranked lists of interventions were presented by their relevance to high-income countries and low–middle-income countries. Results In phase 1, 43 interventions were identified, which had low uptake in practice according to 3042 professionals globally. In phase 2, a shortlist of 15 intervention domains was generated. In phase 3, interventions were deemed acceptable for more than 90 per cent of patients except for reducing general anaesthesia (84 per cent) and re-sterilization of ‘single-use’ consumables (86 per cent). In phase 4, the top three shortlisted interventions for high-income countries were: introducing recycling; reducing use of anaesthetic gases; and appropriate clinical waste processing. In phase 4, the top three shortlisted interventions for low–middle-income countries were: introducing reusable surgical devices; reducing use of consumables; and reducing the use of general anaesthesia. Conclusion This is a step toward environmentally sustainable operating environments with actionable interventions applicable to both high– and low–middle–income countries

The market potential for Alaskan clay products

Submitted by The Mineral Industry Research Laboratory of the University of Alaska to the Department of Economic Development and Planning, Juneau, AlaskaThis study was originally proposed to the Alaska Department of Economic Development and Planning as part of a continuing effort by the Mineral Industry Research Lab of the University of Alaska to strengthen and diversity the mineral industry of the state

Improving benders decomposition using a genetic algorithm

We develop and investigate the performance of a hybrid solution framework for solving mixed-integer linear programming problems. Benders decomposition and a genetic algorithm are combined to develop a framework to compute feasible solutions. We decompose the problem into a master problem and a subproblem. A genetic algorithm along with a heuristic are used to obtain feasible solutions to the master problem, whereas the subproblem is solved to optimality using a linear programming solver. Over successive iterations the master problem is refined by adding cutting planes that are implied by the subproblem. We compare the performance of the approach against a standard Benders decomposition approach as well as against a stand-alone solver (Cplex) on MIPLIB test problems.Genetic algorithm Benders decomposition Mixed-integer linear programs

Field-based phenological model predicts pink bollworm emergence

Control of pink bollworm, a serious pest of cotton in southeastern California, is enhanced by knowing when the different stages of its development will occur. Prediction of pink bollworm development requires a phenological model that relates development to a thermal scale. For spring emergence, the study showed that heat unit accumulation starting Feb. 1 was the best predictor of beginning and peak emergence. This research used field-collected data to establish lower and upper temperature thresholds of 57 degree and 91 degree F (13.9 degree and 32.8 degree), respectively; 409 degree and 918 degree F-days (227 degree and 510 degree C-days) from Feb. 1 to the beginning and the peak of spring emergence, respectively; and 866 degree F-days (492 degree C-days) between generations, from adult moth to adult moth