537 research outputs found

    Technology foresight and industrial strategy in developing countries

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    When Technology Foresight (TF) began to be adopted in industrial countries, it tended to be still somewhat a marginal activity in developing countries. It was then believed that TF and its prediction of the future was a matter that only highly industrialised countries could endeavour to achieve, being more engaged and interested in frontier and "new to the world" innovation. Today globalisation, increased complexity, competition and fast technical change, have radically transformed the range of economic activities that developing countries can perform. Production is internationally fragmented and organised along global value chains. Dense flows of knowledge and technology are available, but need to be fully exploited and employed within coherent industrial strategies. A specialisation by technology and learning has become the dominant paradigm and developing countries must detect opportunities for future technological and productive specialisation in order to catch up and forge ahead. Yet, often TF exercises do not go hand in hand with the design of a concrete policy strategy to promote emerging countries' productive development and catching up. This paper analyses how and to what extent TF programmes are needed in developing countries given the new prevailing global context. It argues that the link between TF and broader industrial development strategy needs to be taken seriously in light of its role to shape technological change and economic growth, and that TF and industrial development strategy need to be coherently designed and implemented. We provide preliminary support to this argument by discussing the theoretical foundations of TF and industrial strategy and their justification, and then reviewing some relevant examples from Brazil, Chile and South Korea

    Morphological and molecular characterization of adults and larvae of Crassicauda spp. (Nematoda: Spirurida) from Mediterranean fin whales Balaenoptera physalus (Linnaeus, 1758)

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    Crassicauda boopis is known to infect the kidneys and vascular system of mysticetes included Balaenoptera physalus and has been recently reported in Mediterranean waters. Identification at the species level relies on the observation of morphological features of the adult parasites, but field conditions during necropsy and the massive reaction of the host's immune system often prevent optimal conservation of the extremities. Moreover, larval stages of Crassicauda have never been described and no sequences are available in public databases to help such identification. Adult and larvae of Crassicauda were isolated from four specimens of B. physalus and studied with morphological and molecular techniques. Specimens of C. anthonyi, C. grampicola and Crassicauda sp. isolated from Ziphius cavirostris, Grampus griseus, Stenella coeruleoalba and Tursiops truncatus respectively were studied as well. Sequences of nuclear markers 18S and ITS-2 and of mitochondrial gene cox1 were obtained and phylogenetic relationships within the genus Crassicauda were analysed. Analysis of the ITS2 grouped the dif- ferent species in accordance with morphological identification, as already evidenced in literature for other Spirurida. A higher intra-specific variability was observed for the cox1 gene, for which two species (C. grampicola and C. anthonyi) did not appear as monophyletic in the tree. Well-developed non-attached larval specimens in the intestinal lumen of a whale calf were molecularly identified as C. boopis, allowing new insights on the life cycle of this species. This work broadens the genetic database on cetaceans parasites, allowing species identi- fication even in challenging field conditions or in poor conservation of the samples; moreover, the first mor- phological description of C. boopis larvae is provided

    DXA-Based Detection of Low Muscle Mass Using the Total Body Muscularity Assessment Index (TB-MAXI): A New Index with Cutoff Values from the NHANES 1999–2004

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    The aims of this study were to investigate age-related changes in total body skeletal muscle mass (TBSMM) and the between-limb asymmetry in lean mass in a large sample of adults. Demographic, anthropometric, and DXA-derived data of National Health and Nutrition Examination Survey participants were considered. The sample included 10,014 participants of two ethnic groups (Caucasians and African Americans). The age-related decline of TBSMM absolute values was between 5% and 6% per decade in males and between 4.5% and 5.0% per decade in females. The adjustment of TBSMM for body surface area (TB-MAXI) showed that muscle mass peaked in the second decade and decreased progressively during the subsequent decades. The following thresholds were identified to distinguish between low and normal TB-MAXI: (i) 10.0 kg/m2 and 11.0 kg/m2 in Caucasian and African American females; and (ii) 12.5 kg/m2 and 14.5 kg/m2 in Caucasian and African American males. The lean asymmetry indices were higher for the lower limbs compared with the upper limbs and were higher for males compared with females. In conclusion, the present study proposes the TB-MAXI and lean asymmetry index, which can be used (and included in DXA reports) as clinically relevant markers for muscle amount and lean distribution

    Navigating challenges:STI policies for sustainable and inclusive development in Latin America

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    This paper explores the challenges and opportunities for Latin America in adopting sustainable development strategies, with a particular focus on Science, Technology and Innovattion (STI) policies. It gathers the insights of a group of distinguished scholars on STI policies, social inclusion and sustainability from the region who participated in the panel organized by the UNESCO Chair during the LALICS* conference held in Asuncion, Paraguay, on 19-21 June 2023.It addresses the challenges that hinder Latin America’s inclusive, sustainable and innovative development process from different perspectives. Highlighted challenges include strong inequality, high informality levels, and low R&D expenditure, heterogeneous productive structure posing obstacles to innovation and their governance. Scholars highlight the role of STI policies and the engagement of academia, government, and business in reducing inequality and promoting social protection, and discuss the technological capabilities needed to address climate change and digitalisation in the region

    Navigating challenges:STI policies for sustainable and inclusive development in Latin America

    Get PDF
    This paper explores the challenges and opportunities for Latin America in adopting sustainable development strategies, with a particular focus on Science, Technology and Innovattion (STI) policies. It gathers the insights of a group of distinguished scholars on STI policies, social inclusion and sustainability from the region who participated in the panel organized by the UNESCO Chair during the LALICS* conference held in Asuncion, Paraguay, on 19-21 June 2023.It addresses the challenges that hinder Latin America’s inclusive, sustainable and innovative development process from different perspectives. Highlighted challenges include strong inequality, high informality levels, and low R&D expenditure, heterogeneous productive structure posing obstacles to innovation and their governance. Scholars highlight the role of STI policies and the engagement of academia, government, and business in reducing inequality and promoting social protection, and discuss the technological capabilities needed to address climate change and digitalisation in the region

    Putting the barker theory into the future : time to act on preventing pediatric obesity

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    Growth and development are key characteristics of childhood and sensitive markers of health and adequate nutrition. The first 1000 days of life\u2014conception through 24 months of age\u2014represent a fundamental period for development and thus the prevention of childhood obesity and its adverse consequences is mandatory. There are many growth drivers during this complex phase of life,such as nutrition,genetic and epigenetic factors,and hormonal regulation. The challenge thus involves maximizing the potential for normal growth without increasing the risk of associated disorders. The Mediterranean Nutrition Group (MeNu Group),a group of researchers of the Mediterranean Region,in this Special Issue titled \u201cPrevent Obesity in the First 1000 Days\u201d,presented results that advanced the science of obesity risk factors in early life,coming both from animal model studies and studies in humans. In the future,early-life intervention designs for the prevention of pediatric obesity will need to look at different strategies,and the MeNu Group is available for guidance regarding an appropriate conceptual framework to accomplish either prevention or treatment strategies to tackle pediatric obesity

    Differential Maternal Feeding Practices, Eating Self-Regulation, and Adiposity in Young Twins

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    Restrictive feeding is associated with childhood obesity; however, this could be due to other factors that drive children to overeat and parents to restrict (eg, child genetics). Using a twin design to better control for confounders, we tested differences in restrictive feeding within families in relation to differences in twins’ self-regulatory eating and weight status

    US pediatric population-level associations of DXA-measured percentage of body fat with four BMI metrics with cutoffs

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    ObjectiveFour body mass index (BMI) metrics—BMI, BMI z-score, BMI percentile, and BMI%—are commonly used as proxy measures for children's adiposity. We sought to determine a BMI metric that is most strongly associated with measured percentage of body fat (%BF) in the US pediatric population stratified by sex, age and race/ethnicity, and to determine cutoffs that maximize the association for each BMI metric.Subjects, Design and Methods%BF was measured by DXA among N=6120 US boys and girls aged 8.0 to 17.9 years old from NHANES 1999-2004. We fit piece-wise linear regression models with cutoffs to %BF data using each BMI metric as the predictor stratified by sex, race/ethnicity and age. The slopes were modeled differently before and after the cutoffs which were determined based on grid searches.ResultsBMI z-score was in general most strongly associated with %BF for both boys and girls. The associations of the four BMI metrics were lowest for boys aged 12-13.9 years and girls aged 16-17.9 years, and strongest for Mexican-American boys and for non-Hispanic black girls. Overall, the associations were stronger for girls than for boys. In boys, BMI had the lowest association with %BF (R2=0.39) for all ages combined. The fold changes in slopes before and after cutoffs were greatest in general for BMI percentiles regardless of age, sex and race/ethnicity. BMI z-score cutoffs were 0.4 for both boys and girls for all ages combined. Except for BMI, the slopes after the cutoffs were in general greater than those before.ConclusionsAll BMI metrics were strongly associated with %BF when stratified by age and race/ethnicity except that BMI was the least associated with %BF in boys for all ages combined. Overall, BMI z-score was superior for evaluation of %BF, and its cutoff of 0.4 can also serve as a threshold for careful monitoring of weight status

    South-South technology transfer of low-carbon innovation: large Chinese hydropower dams in Cambodia

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    Large dams have been controversially debated for decades due to their large‐scale and often irreversible social and environmental impacts. In the pursuit of low‐carbon energy and climate change mitigation, hydropower is experiencing a new renaissance. At the forefront of this renaissance are Chinese actors as the world's largest hydropower dam‐builders. This paper aims to discuss the role of South–South technology transfer of low‐carbon energy innovation and its opportunities and barriers by using a case study of the first large Chinese‐funded and Chinese‐built dam in Cambodia. Using the Kamchay Dam as an example, the paper finds that technology transfer can only be fully successful when host governments and organizations have the capacity to absorb new technologies. The paper also finds that technology transfer in the dam sector needs to go beyond hardware and focus more on the transfer of expertise, skills and knowledge to enable long‐term sustainable development

    Dog filariosis in the Lazio region (Central Italy): first report on the presence of Dirofilaria repens

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    BACKGROUND: Epidemiological investigations were carried out in the Lazio Region to assess the status of canine filariosis and to evaluate the actual risk for veterinary and medical public health. METHODS: Since August 2001 to June 2003, a total of 972 canine blood samples, collected in public kennels and from private owners animals of the 5 Provinces of the Region, were tested. The presence of filarial parasites was evaluated by microscopy and bio-molecular techniques; the species identification was performed by means of the same diagnostic tools. RESULTS: A total of 17/972 (1.75%; 95%CI 1.06%–2.85%) blood samples were parasitized by D. repens,13 out them drawn by dogs resident in the Province of Roma, and 4 in the other provinces. Multivariate analysis was performed in order to evaluate the association between filariosis and risk factors. The origin from coastal territories seems to be a significant risk factor to acquire the infection. CONCLUSION: This is the first report of canine filariosis in the Lazio Region, where D. repens was before reported only in foxes. The risk of human zoonotic infection is stressed, and the absence of other filarial species is discusse
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