Cold molecular welding study Final report, Jun. 15, 1966 - Jun. 14, 1967

Cold molecular welding characteristics of metal pellets on stainless steel wear plate

NASA Contributions to Development of Special-Purpose Thermocouples. A Survey

The thermocouple has been used for measuring temperatures for more than a century, but new materials, probe designs, and techniques are continually being developed. Numerous contributions have been made by the National Aeronautics and Space Administration and its contractors in the aerospace program. These contributions have been collected by Midwest Research Institute and reported in this publication to enable American industrial engineers to study them and adapt them to their own problem areas. Potential applications are suggested to stimulate ideas on how these contributions can be used

Cold molecular welding study in ultra-high vacuum Final report, 8 Oct. 1964 - 17 Dec. 1965

Cold molecular welding in ultrahigh vacuum of metals for use in Apollo projec

Network Models

Networks can be combined in various ways, such as overlaying one on top of another or setting two side by side. We introduce "network models" to encode these ways of combining networks. Different network models describe different kinds of networks. We show that each network model gives rise to an operad, whose operations are ways of assembling a network of the given kind from smaller parts. Such operads, and their algebras, can serve as tools for designing networks. Technically, a network model is a lax symmetric monoidal functor from the free symmetric monoidal category on some set to $\mathbf{Cat}$, and the construction of the corresponding operad proceeds via a symmetric monoidal version of the Grothendieck construction.Comment: 46 page

The Development of Lutheranism in the Pacific Northwest with Specific Reference to the Northwest District, Lutheran Church--Missouri Synod

The Development of Lutheranism in the Pacific Northwest with Specific Reference to the Northwest District, Lutheran Church--Missouri Syno

Determination of atmospheric moisture structure and infrared cooling rates from high resolution MAMS radiance data

This program has applied Multispectral Atmospheric Mapping Sensor (MAMS) high resolution data to the problem of monitoring atmospheric quantities of moisture and radiative flux at small spatial scales. MAMS, with 100-m horizontal resolution in its four infrared channels, was developed to study small scale atmospheric moisture and surface thermal variability, especially as related to the development of clouds, precipitation, and severe storms. High-resolution Interferometer Sounder (HIS) data has been used to develop a high spectral resolution retrieval algorithm for producing vertical profiles of atmospheric temperature and moisture. The results of this program are summarized and a list of publications resulting from this contract is presented. Selected publications are attached as an appendix

Planck Fluctuations, Measurement Uncertainties and the Holographic Principle

Starting from a critical analysis of recently reported surprisingly large uncertainties in length and position measurements deduced within the framework of quantum gravity, we embark on an investigation both of the correlation structure of Planck scale fluctuations and the role the holographic hypothesis is possibly playing in this context. While we prove the logical independence of the fluctuation results and the holographic hypothesis (in contrast to some recent statements in that direction) we show that by combining these two topics one can draw quite strong and interesting conclusions about the fluctuation structure and the microscopic dynamics on the Planck scale. We further argue that these findings point to a possibly new and generalized form of quantum statistical mechanics of strongly (anti)correlated systems of degrees of freedom in this fundamental regime.Comment: 19 pages, Latex, no figures, some new references, to appear ModPhysLett

Not Just An Ankle Sprain

49-year-old male with past medical history of hypertension who presents to the sports medicine clinic with a five-year history of left lateral foot pain.https://scholarlycommons.henryford.com/merf2020caserpt/1120/thumbnail.jp

Effects of spaceflight on the proliferation of jejunal mucosal cells

The purpose of this project was to test the hypothesis that the generalized, whole body decrease in synthetic activity due to microgravity conditions encountered during spaceflight would be demonstrable in cells and tissues characterized by a rapid rate of turnover. Jejunal mucosal cells were chosen as a model since these cells are among the most rapidly proliferating in the body. Accordingly, the percentage of mitotic cells present in the crypts of Lieberkuhn in each of 5 rats flown on the COSMOS 2044 mission were compared to the percentage of mitotic cells present in the crypts in rats included in each of 3 ground control groups (i.e., vivarium, synchronous and caudal-elevated). No significant difference (p greater than .05) was detected in mitotic indices between the flight and vivarium group. Although the ability of jejunal mucosal cells to divide by mitosis was not impaired in flight group, there was, however, a reduction in the length of villi and depth of crypts. The concommitant reduction in villus length and crypth depth in the flight group probably reflects changes in connective tissue components within the core of villi

TRIP13 is a protein-remodeling AAA+ ATPase that catalyzes MAD2 conformation switching.

The AAA+ family ATPase TRIP13 is a key regulator of meiotic recombination and the spindle assembly checkpoint, acting on signaling proteins of the conserved HORMA domain family. Here we present the structure of the Caenorhabditis elegans TRIP13 ortholog PCH-2, revealing a new family of AAA+ ATPase protein remodelers. PCH-2 possesses a substrate-recognition domain related to those of the protein remodelers NSF and p97, while its overall hexameric architecture and likely structural mechanism bear close similarities to the bacterial protein unfoldase ClpX. We find that TRIP13, aided by the adapter protein p31(comet), converts the HORMA-family spindle checkpoint protein MAD2 from a signaling-active 'closed' conformer to an inactive 'open' conformer. We propose that TRIP13 and p31(comet) collaborate to inactivate the spindle assembly checkpoint through MAD2 conformational conversion and disassembly of mitotic checkpoint complexes. A parallel HORMA protein disassembly activity likely underlies TRIP13's critical regulatory functions in meiotic chromosome structure and recombination