682 research outputs found

    Design of a 10.8 kWh, 28V Ni-MH Battery Using Commercial Ni-MH Cells

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    This paper describes the design of a 10.8 kWh, 28V, Ni-MH battery using commercial off-the shelf (COTS) 4/3A Ni-MH cells for the X-38 vehicle, an experimental version of the Crew Return Vehicle (CRY). This will be an autonomous vehicle that will enable International Space Station crews to return to earth in the event of a medical, or other, emergency. The X-38 will be powered by 3 batteries: a 32 V primary battery, which will power the vehicle avionics for up to 7 hours for a loiter and de-orbit phase of the descent; a 28 V Ni-MH battery which will take over for the primary battery after de-orbit until landing, and a 270V Ni-Cd battery, which will be used to power electromechanical actuators and the winches controlling a parachute for landing

    Rethinking the Quality and Relevance of University Education in Kenya from Entrepreneurial Perspective

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    Many stakeholders have expressed concern about the many graduates from Kenyan universities who after qualifying, not only fail to get jobs but also fail to venture into alternative forms of engagement to earn their livelihood, a scenario that raises question as to the quality and relevance of University education they got. The concerns being raised calls for rethinking of the quality and relevance of university education in Kenya. This study, therefore, sought to investigate the propensity of university education in Kenya to inculcate entrepreneurial culture in graduates. The theory of planned behavior formed the theoretical foundation of the study. The study adopted a triangular design approach where views relating to entrepreneurial culture were sought from final year students from one public and one private university. The study targeted 3146 final year students drawn from University of Kabianga, (2272) and Kabarak University (874). From this, a sample of 614 students proportionately distributed among the two universities was drawn. Entrepreneurial environment was found to be more or less the same in both private and public universities recording moderate score. However, public university scored slightly higher. In conclusion, there is no significant difference in the levels of preference for entrepreneurship when comparison is made between public and private universities in Kenya. Arising from the current finding, the study recommends provision of better entrepreneurial support system. It will be preemptive to conclude that University education in Kenyan universities nature entrepreneurial culture Keywords: Entrepreneurial culture, Quality, relevance, University education DOI: 10.7176/JEP/10-9-03 Publication date:March 31st 201

    The Influence of Brand Awareness, Brand Image, and Service Quality Inflight Catering on Saudi Consumer Satisfaction Arabian Airlines

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    This study aims to test and analyze brand awareness, brand image, and quality of Aerofood ACS catering services to the consumer satisfaction of Saudi Arabian airlines. The research method used in this research is descriptive method. The objects of this study were 171 Arab Saudi airline staff and cabin crew. The approach used in this research is the Structural Equation Model (SEM) with Smart-PLS analysis tools. The results showed brand awareness had a positive and significant effect on customer satisfaction on Saudi Arabian airlines. Brand image has a positive and significant effect on customer satisfaction on Saudi Arabian airlines. Quality of service has a positive and significant effect on customer satisfaction on Saudi Arabian airlines. Keywords: Brand awareness, Brand image, Service quality, Consumer Satisfaction DOI: 10.7176/JMCR/71-01 Publication date:September 30th 202

    Habitação de Interesse Social no Centro Histórico de São Luís - MA. Uma análise Arquitetónica e Construtiva.

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    O presente Projeto Aplicado, intitulado Habitação de interesse social no centro histórico de São Luís/MA: uma análise arquitetônica e construtiva de dois estudos de caso com o objetivo de verificar prováveis fatores que possam estar interferindo nos processos de intervenções em habitação em centros históricos. O Brasil tem um déficit habitacional de 7,757 milhões de moradias. A insuficiência de ofertas habitacionais para esta demanda contribui para o crescimento desta parcela da população em favelas e loteamentos irregulares nas periferias das cidades, áreas desprovidas, na maioria das vezes, de infraestrutura básica, como água, energia elétrica, esgoto canalizado, transporte público e serviços essenciais como postos médicos, escolas, segurança e estruturas de lazer. Paralelamente, diversas cidades apresentam um esvaziamento populacional das áreas centrais consolidadas, regiões com um grande capital investido, infraestrutura, acessibilidade e oportunidades de trabalho. A partir da década de 1970, os centros urbanos das principais cidades brasileiras vêm perdendo moradores, especialmente de famílias de renda média e alta, causando baixa densidade populacional e grande quantidade de imóveis vazios ou subutilizados. O Governo do Estado do Maranhão, através do Programa de Preservação e Revitalização do Centro Histórico de São Luís (PPRCHSL), entre 1995 e 2002 reabilitou alguns edifícios na ambiência do centro histórico para habitação de interesse social destinadas a servidores públicos estaduais e, dentre esses, foram selecionados como estudos de caso os imóveis às Rua da Estrela, n.º 350 e Rua da Palma, n. º 336, ambos na Praia Grande, Centro Histórico de São Luís. Foi utilizado o método de pesquisa exploratória do tipo Estudo de Caso com perfil por amostragem. Foram feitas análises dos projetos de intervenção baseada especificamente na funcionalidade dos espaços edificados habitados, comparando as exigências de funcionalidade previstas no Código de Construções do Município e na norma ABNT NBR 15575. Espera-se, após análise dos dados obtidos contribuir para possíveis melhorias em futuros projetos de reabilitação de edifícios para habitação e consequente preservação do patrimônio e revitalização do centro histórico

    Actin-Interacting Protein 1 Contributes to Intranuclear Rod Assembly in Dictyostelium discoideum

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    Intranuclear rods are aggregates consisting of actin and cofilin that are formed in the nucleus in consequence of chemical or mechanical stress conditions. The formation of rods is implicated in a variety of pathological conditions, such as certain myopathies and some neurological disorders. It is still not well understood what exactly triggers the formation of intranuclear rods, whether other proteins are involved, and what the underlying mechanisms of rod assembly or disassembly are. In this study, Dictyostelium discoideum was used to examine appearance, stages of assembly, composition, stability, and dismantling of rods. Our data show that intranuclear rods, in addition to actin and cofilin, are composed of a distinct set of other proteins comprising actin-interacting protein 1 (Aip1), coronin (CorA), filactin (Fia), and the 34 kDa actin-bundling protein B (AbpB). A finely tuned spatio-temporal pattern of protein recruitment was found during formation of rods. Aip1 is important for the final state of rod compaction indicating that Aip1 plays a major role in shaping the intranuclear rods. In the absence of both Aip1 and CorA, rods are not formed in the nucleus, suggesting that a sufficient supply of monomeric actin is a prerequisite for rod formation

    Formation of Cytoplasmic Actin-Cofilin Rods is Triggered by Metabolic Stress and Changes in Cellular pH

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    Actin dynamics plays a crucial role in regulating essential cell functions and thereby is largely responsible to a considerable extent for cellular energy consumption. Certain pathological conditions in humans, like neurological disorders such as Alzheimer’s disease or amyotrophic lateral sclerosis (ALS) as well as variants of nemaline myopathy are associated with cytoskeletal abnormalities, so-called actin-cofilin rods. Actin-cofilin rods are aggregates consisting mainly of actin and cofilin, which are formed as a result of cellular stress and thereby help to ensure the survival of cells under unfavorable conditions. We have used Dictyostelium discoideum, an established model system for cytoskeletal research to study formation and principles of cytoplasmic actin rod assembly in response to energy depletion. Experimentally, depletion of ATP was provoked by addition of either sodium azide, dinitrophenol, or 2-deoxy-glucose, and the formation of rod assembly was recorded by live-cell imaging. Furthermore, we show that hyperosmotic shock induces actin-cofilin rods, and that a drop in the intracellular pH accompanies this condition. Our data reveal that acidification of the cytoplasm can induce the formation of actin-cofilin rods to varying degrees and suggest that a local reduction in cellular pH may be a cause for the formation of cytoplasmic rods. We hypothesize that local phase separation mechanistically triggers the assembly of actin-cofilin rods and thereby influences the material properties of actin structures

    Emission Minimization of a Two-Stage Sour Water Stripping Unit Using Surrogate Models for Improving Heat Duty Control

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    Sour water are aqueous waste streams from oil refining operations, heavily contaminated with hydrogen sulfide and ammonia, which need to be stripped before reuse or disposal, avoiding damages to process and environment. Two-stage sour water stripper units are the most common technology to treat sour water for hydrogen sulfide and ammonia separation to produce reusable water and send these species respectively to Claus and ammonia plants. The first stage of a two-stage sour water unit is responsible for properly splitting hydrogen sulfide and ammonia. This work uses surrogate models to predict the limiting point of hydrogen sulfide separation in the first stage of a sour water unit, allowing more efficient heat duty control strategies to achieve the difficult split of hydrogen sulfide and ammonia and simultaneously lowering heat consumption. Failure of compliance to this limit results in unspecified stripped gas from the first stage, impeding it to directed to Claus plant, entailing loss of sulfur production and higher load of pollutant emissions from flared gases. Therefore, a precise surrogate predictor was developed to dynamically define a quasi-optimum set-point to the controller of the first stage reboiler duty based on dynamic disturbances – the first stage input factors to the surrogate model, such as hydrogen sulfide and ammonia contents of the sour water. The new control policy outperformed the traditional first stage ratio control in terms of stripped gas composition and plant stability

    The value of hope: development and validation of a contextual measure of hope among people living with HIV in urban Tanzania a mixed methods exploratory sequential study.

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    BACKGROUND: Hope or hopefulness enhances coping and improves quality of life in persons with chronic or incurable illnesses. Lack of hope is associated with depression and anxiety, which impact negatively on quality of life. In Tanzania, where HIV prevalence is high, the rates of depression and anxiety are over four times higher among people living with HIV (PLH) compared to persons not infected and contribute annual mortality among PLH. Tanzania has a shortage of human resources for mental health, limiting access to mental health care. Evidence-based psychosocial interventions can complement existing services and improve access to quality mental health services in the midst of human resource shortages. Facilitating hope can be a critical element of non-pharmacological interventions which are underutilized, partly due to limited awareness and lack of hope measures, adapted to accommodate cultural context and perspectives of PLH. To address this gap, we developed and validated a local hope measure among PLH in Tanzania. METHODS: Two-phased mixed methods exploratory sequential study among PLH. Phase I was Hope-related items identification using deductive, inductive approaches and piloting. Phase II was an evaluation of psychometric properties at baseline and 24 months. Classical test theory, exploratory, confirmatory factor analysis (CFA) were used. RESULTS: Among 722 PLH, 59% were women, mean age was 39.3 years, and majority had primary school level of education. A total of 40 hope items were reduced to 10 in a three-factor solution, explaining 69% of variance at baseline, and 93% at follow-up. Internal consistency Cronbach's alpha was 0.869 at baseline and 0.958 at follow-up. The three-factor solution depicted: positive affect; cognition of effectiveness of HIV care; and goals/plans/ future optimism. Test-retest reliability was good (r = 0.797) and a number of indices were positive for CFA model fit, including Comparative Fit Index of 0.984. CONCLUSION: The developed local hope scale had good internal reliability, validity, and its dimensionality was confirmed against expectations. The fewer items for hope assessment argue well for its use in busy clinical settings to improve HIV care in Tanzania. Hope in this setting could be more than cognitive goal thinking, pathway and motivation warranting more research. TRIAL REGISTRATION: The intervention was registered in USA ClinicalTrials.gov on September 26, 2012, Registration number: NCT01693458
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