731 research outputs found
Sindicalismo, superpopulação relativa e formas de luta no Brasil e na Argentina
O artigo analisa a relação entre o movimento sindical e os desempregados no Brasil e na Argentina, de 1990 a 2002, a partir de uma reflexão sobre as duas principais centrais sindicais de cada país: a Central Única dos Trabalhadores (CUT) e a Força Sindical (FS), no caso brasileiro; a Confederación General del Trabajo (CGT) e a Central de los Trabajadores de la Argentina (CTA), no caso argentino. Como marco teórico, parte principalmente da teoria da superpopulação relativa de Marx e analisa como os vínculos entre o sindicalismo e os trabalhadores sem emprego contribuem para explicar, de maneira mais ampla, a unidade e fratura entre o exército de operários ativo e o exército de operários de reserva
Universal approximation of multi-copy states and universal quantum lossless data compression
We have proven that there exists a quantum state approximating any multi-copy
state universally when we measure the error by means of the normalized relative
entropy. While the qubit case was proven by Krattenthaler and Slater (IEEE
Trans. IT, 46, 801-819 (2000); quant-ph/9612043), the general case has been
open for more than ten years. For a deeper analysis, we have solved the
mini-max problem concerning `approximation error' up to the second order.
Furthermore, we have applied this result to quantum lossless data compression,
and have constructed a universal quantum lossless data compression
Attosecond double-slit experiment
A new scheme for a double-slit experiment in the time domain is presented.
Phase-stabilized few-cycle laser pulses open one to two windows (``slits'') of
attosecond duration for photoionization. Fringes in the angle-resolved energy
spectrum of varying visibility depending on the degree of which-way information
are observed. A situation in which one and the same electron encounters a
single and a double slit at the same time is discussed. The investigation of
the fringes makes possible interferometry on the attosecond time scale. The
number of visible fringes, for example, indicates that the slits are extended
over about 500as.Comment: 4 figure
Differential Mitochondrial Toxicity Screening and Multi- Parametric Data Analysis
Early evaluation of new drug entities for their potential to cause mitochondrial dysfunction is becoming an important task for drug development. Multi-parametric high-content screening (mp-HCS) of mitochondrial toxicity holds promise as a lead in-vitro strategy for drug testing and safety evaluations. In this study, we have developed a mp-HCS and multi-parametric data analysis scheme for assessing cell responses to induced mitochondrial perturbation. The mp-HCS measurements are shown to be robust enough to allow for quantitative comparison of biological systems with different metabolic pathways simulated by alteration of growth media. Substitution of medium glucose for galactose sensitized cells to drug action and revealed novel response parameters. Each compound was quantitatively characterized according to induced phenotypic changes of cell morphology and functionality measured by fluorescent biomarkers for mitochondrial activity, plasma membrane permeability, and nuclear morphology. Descriptors of drug effects were established by generation of a SCRIT (Specialized-Cell-Response-to-Induced-Toxicity) vector, consisting of normalized statistical measures of each parameter at each dose and growth condition. The dimensionality of SCRIT vectors depends on the number of parameters chosen, which in turn depends on the hypothesis being tested. Specifically, incorporation of three parameters of response into SCRIT vectors enabled clustering of 84 training compounds with known pharmacological and toxicological activities according to the degree of toxicity and mitochondrial involvement. Inclusion of 6 parameters enabled the resolution of more subtle differences between compounds within a common therapeutic class; scoring enabled a ranking of statins in direct agreement with clinical outcomes. Comparison of drug-induced changes required variations in glucose for separation of mitochondrial dysfunction from other types of cytotoxicity. These results also demonstrate that the number of drugs in a training set, the choice of parameters used in analysis, and statistical measures are fundamental for specific hypothesis testing and assessment of quantitative phenotypic differences
de Broglie waves as the "Bridge of Becoming" between quantum theory and relativity
It is hypothesized that de Broglie's 'matter waves' provide a dynamical basis
for Minkowski spacetime in an antisubstantivalist or relational account. The
relativity of simultaneity is seen as an effect of the de Broglie oscillation
together with a basic relativity postulate, while the dispersion relation from
finite rest mass gives rise to the differentiation of spatial and temporal
axes. Thus spacetime is seen as not fundamental, but rather as emergent from
the quantum level. A result by Solov'ev which demonstrates that time is not an
applicable concept at the quantum level is adduced in support of this claim.
Finally, it is noted that de Broglie waves can be seen as the "bridge of
becoming" discussed by Elitzur and Dolev (2005).Comment: Forthcoming in Foundations of Science; reference added to recent work
of Dolc
Internally Electrodynamic Particle Model: Its Experimental Basis and Its Predictions
The internally electrodynamic (IED) particle model was derived based on
overall experimental observations, with the IED process itself being built
directly on three experimental facts, a) electric charges present with all
material particles, b) an accelerated charge generates electromagnetic waves
according to Maxwell's equations and Planck energy equation and c) source
motion produces Doppler effect. A set of well-known basic particle equations
and properties become predictable based on first principles solutions for the
IED process; several key solutions achieved are outlined, including the de
Broglie phase wave, de Broglie relations, Schr\"odinger equation, mass,
Einstein mass-energy relation, Newton's law of gravity, single particle self
interference, and electromagnetic radiation and absorption; these equations and
properties have long been broadly experimentally validated or demonstrated. A
specific solution also predicts the Doebner-Goldin equation which emerges to
represent a form of long-sought quantum wave equation including gravity. A
critical review of the key experiments is given which suggests that the IED
process underlies the basic particle equations and properties not just
sufficiently but also necessarily.Comment: Presentation at the 27th Int Colloq on Group Theo Meth in Phys, 200
Increased male reproductive success in Ts65Dn “Down syndrome” mice
The Ts65Dn mouse is trisomic for orthologs of about half the genes on Hsa21. A number of phenotypes in these trisomic mice parallel those in humans with trisomy 21 (Down syndrome), including cognitive deficits due to hippocampal malfunction that are sufficiently similar to human that “therapies” developed in Ts65Dn mice are making their way to human clinical trials. However, the impact of the model is limited by availability. Ts65Dn cannot be completely inbred and males are generally considered to be sterile. Females have few, small litters and they exhibit poor care of offspring, frequently abandoning entire litters. Here we report identification and selective breeding of rare fertile males from two working colonies of Ts65Dn mice. Trisomic offspring can be propagated by natural matings or by in vitro fertilization (IVF) to produce large cohorts of closely related siblings. The use of a robust euploid strain as recipients of fertilized embryos in IVF or as the female in natural matings greatly improves husbandry. Extra zygotes cultured to the blastocyst stage were used to create trisomic and euploid embryonic stem (ES) cells from littermates. We developed parameters for cryopreserving sperm from Ts65Dn males and used it to produce trisomic offspring by IVF. Use of cryopreserved sperm provides additional flexibility in the choice of oocyte donors from different genetic backgrounds, facilitating rapid production of complex crosses. This approach greatly increases the power of this important trisomic model to interrogate modifying effects of trisomic or disomic genes that contribute to trisomic phenotypes
Lambda and Antilambda polarization from deep inelastic muon scattering
We report results of the first measurements of Lambda and Antilambda
polarization produced in deep inelastic polarized muon scattering on the
nucleon. The results are consistent with an expected trend towards positive
polarization with increasing x_F. The polarizations of Lambda and Antilambda
appear to have opposite signs. A large negative polarization for Lambda at low
positive x_F is observed and is not explained by existing models.A possible
interpretation is presented.Comment: 9 pages, 2 figure
Universal coding for classical-quantum channel
We construct a universal code for stationary and memoryless classical-quantum
channel as a quantum version of the universal coding by Csisz\'{a}r and
K\"{o}rner. Our code is constructed by the combination of irreducible
representation, the decoder introduced through quantum information spectrum,
and the packing lemma
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