Getter pumping

A surface may provide a useful pumping action when able to retain adsorbed gas molecules for the duration of a given experiment. To fulfil this condition at room temperature, strong binding forces, as those resulting from chemical reactions, are required. Materials able to react with gases to form stable chemical compounds are called getters. The two main families of getters (evaporable and non-evaporable, or NEG) are presented and discussed. Special emphasis is placed on the NEG strips currently used for the vacuum systems of particle accelerators, and on the newly developed NEG thin-film coatings, in view of their possible future applications

Non-singlet QCD analysis of F_2(x,Q^2) up to NNLO

The significance of NNLO (3-loop) QCD contributions to the flavor non-singlet sector of F_2^ep and F_2^ed has been studied as compared to uncertainties (different factorization schemes, higher twist and QED contributions) of standard NLO (and LO) QCD analyses. The latter effects turn out to be comparable in size to the NNLO contributions. Therefore the minute NNLO effects are not observable with presently available data on non-singlet structure functions.Comment: 14 pages, 2 figure

Implications of Hadron Collider Observables on Parton Distribution Function Uncertainties

Standard parton distribution function sets do not have rigorously quantified uncertainties. In recent years it has become apparent that these uncertainties play an important role in the interpretation of hadron collider data. In this paper, using the framework of statistical inference, we illustrate a technique that can be used to efficiently propagate the uncertainties to new observables, assess the compatibility of new data with an initial fit, and, in case the compatibility is good, include the new data in the fit.Comment: 22 pages, 5 figure

Structure Functions in Deep Inelastic Lepton-Nucleon Scattering

Latest results on structure functions, as available at the Lepton-Photon Symposium 1999, are presented. This report focusses on three experimental areas: new structure function measurements, in particular from HERA at low x and high Q2; results on light and heavy flavour densities; determinations of the gluon distribution and of alpha_s. As the talk was delivered at a historic moment and place, a few remarks were added recalling the exciting past and looking into the promising future of deep inelastic scattering.Comment: 27 pages, latex, 15 figures, Talk at Lepton-Photon Symposium, Stanford, August 199

Small x Behavior of Parton Distributions from the Observed Froissart Energy Dependence of the Deep Inelastic Scattering Cross Section

We fit the reduced cross section for deep-inelastic electron scattering data to a three parameter ln^2 s fit, A + beta ln^2 (s/s_0), where s= [Q^2/x] (1-x) + m^2, and Q^2 is the virtuality of the exchanged photon. Over a wide range in Q^2 (0.11 < Q^2 < 1200 GeV^2) all of the fits satisfy the logarithmic energy dependence of the Froissart bound. We can use these results to extrapolate to very large energies and hence to very small values of Bjorken x -- well beyond the range accessible experimentally. As Q^2 --> infinity, the structure function F_2^p(x, Q^2) exhibits Bjorken scaling, within experimental errors. We obtain new constraints on the behavior of quark and antiquark distribution functions at small x.Comment: 10 pages, 2 figure

Strings on the deformed T^{1,1}: giant magnon and single spike solutions

In this paper we find giant magnon and single spike string solutions in a sector of the gamma-deformed conifold. We examine the dispersion relations and find a behavior analogous to the undeformed case. The transcendental functional relations between the conserved charges are shifted by certain gamma-dependent term. The latter is proportional to the total momentum and thus qualitatively different from known cases.Comment: 35 pages, no figure

Cascading Quivers from Decaying D-branes

We use an argument analogous to that of Kachru, Pearson and Verlinde to argue that cascades in L^{a,b,c} quiver gauge theories always preserve the form of the quiver, and that all gauge groups drop at each step by the number M of fractional branes. In particular, we demonstrate that an NS5-brane that sweeps out the S^3 of the base of L^{a,b,c} destroys M D3-branes.Comment: 11 pages, 1 figure; v2: references adde

Protein kinase CK2 is widely expressed in follicular, Burkitt and diffuse large B-cell lymphomas and propels malignant B-cell growth.

Serine-threonine kinase CK2 is highly expressed and pivotal for survival and proliferation in multiple myeloma, chronic lymphocytic leukemia and mantle cell lymphoma. Here, we investigated the expression of \u3b1 catalytic and \u3b2 regulatory CK2 subunits by immunohistochemistry in 57 follicular (FL), 18 Burkitt (BL), 52 diffuse large B-cell (DLBCL) non-Hodgkin lymphomas (NHL) and in normal reactive follicles. In silico evaluation of available Gene Expression Profile (GEP) data sets from patients and Western blot (WB) analysis in NHL cell-lines were also performed. Moreover, the novel, clinical-grade, ATP-competitive CK2-inhibitor CX-4945 (Silmitasertib) was assayed on lymphoma cells. CK2 was detected in 98.4% of cases with a trend towards a stronger CK2\u3b1 immunostain in BL compared to FL and DLBCL. No significant differences were observed between Germinal Center B (GCB) and non-GCB DLBCL types. GEP data and WB confirmed elevated CK2 mRNA and protein levels as well as active phosphorylation of specific targets in NHL cells. CX-4945 caused a dose-dependent growth-arresting effect on GCB, non-GCB DLBCL and BL cell-lines and it efficiently shut off phosphorylation of NF-\u3baB RelA and CDC37 on CK2 target sites. Thus, CK2 is highly expressed and could represent a suitable therapeutic target in BL, FL and DLBCL NHL