Position estimating in peer-to-peer networks

We present two algorithms for indoor positioning estimation in peer-to-peer networks. The setup is a network of two types of devices: reference devices with a known location and blindfolded devices that can determine distances to reference devices and each other. From this information the blindfolded devices try to estimate their positions. A typical scenario is navigation inside a shopping mall where devices in the parking lot can make contact with GPS satellites, whereas devices inside the building make contact with each other, devices on the parking lot, and devices fixed to the building. The devices can measure their in-between distances, with some measurement error, and exchange positioning information. However, other devices might only know their position with some error. We present two algorithms for positioning estimation in such a peer-to-peer network. The first one is purely geometric and is based on Euclidean geometry and intersecting spheres. We rewrite the information to a linear system, which is typically overdetermined. We use least squares to ??nd the best estimate for a device its position. The second approach can be considered as a probabilistic version of the geometric approach. We estimate the probability density function that a device is located at a position given a probability density function for the positions of the other devices in the network, and a probability density function of the measured distances. First we study the case with a distance measurement to a single other user, then we focus on multiple other users. We give an approximation algorithm that is the probabilistic analogue of the intersecting spheres method. We show some simulated results where ambiguous data lead to well defined probability distributions for the position of a device. We conclude with some open questions

PU(2) monopoles and links of top-level Seiberg-Witten moduli spaces

This is the first of two articles in which we give a proof - for a broad class of four-manifolds - of Witten's conjecture that the Donaldson and Seiberg-Witten series coincide, at least through terms of degree less than or equal to c-2, where c is a linear combination of the Euler characteristic and signature of the four-manifold. This article is a revision of sections 1-3 of an earlier version of the article dg-ga/9712005, now split into two parts, while a revision of sections 4-7 of that earlier version appears in a recently updated dg-ga/9712005. In the present article, we construct virtual normal bundles for the Seiberg-Witten strata of the moduli space of PU(2) monopoles and compute their Chern classes.Comment: Journal fur die Reine und Angewandte Mathematik, to appear; 64 page

Are mice good models for human neuromuscular disease? Comparing muscle excursions in walking between mice and humans

The mouse is one of the most widely used animal models to study neuromuscular diseases and test new therapeutic strategies. However, findings from successful pre-clinical studies using mouse models frequently fail to translate to humans due to various factors. Differences in muscle function between the two species could be crucial but often have been overlooked. The purpose of this study was to evaluate and compare muscle excursions in walking between mice and humans

Agonists for the adenosine A(1) receptor with tunable residence time: a case for nonribose 4-Amino-6-aryl-5-cyano-2-thiopyrimidines

Medicinal Chemistr

Controlled Radical Polymerization of Vinyl Acetate Mediated by a Bis(imino)pyridine Vanadium Complex

Source type: Prin

Effectiveness of interspinous implant surgery in patients with intermittent neurogenic claudication: a systematic review and meta-analysis

Item does not contain fulltextINTRODUCTION: Despite an increasing implantation rate of interspinous process distraction (IPD) devices in the treatment of intermittent neurogenic claudication (INC), definitive evidence on the clinical effectiveness of implants is lacking. The main objective of this review was to perform a meta-analysis of all systematic reviews, randomized clinical trials and prospective cohort series to quantify the effectiveness of IPDs and to evaluate the potential side-effects. METHODS: Data from all studies prospectively describing clinical results based on validated outcome scales and reporting complications of treatment of patients with INC with IPD placement. We searched MEDLINE, EMBASE, Web of Science, Cochrane (CENTRAL), CINAHL, Academic Search Premier, Science Direct up to July 2010. Studies describing patients with INC caused by lumbar stenosis, reporting complication rate and reporting based on validated outcome scores, were eligible. Studies with only instrumented IPD results were excluded. RESULTS: Eleven studies eligible studies were identified. Two independently RCTs and eight prospective cohorts were available. In total 563 patients were treated with IPDs. All studies showed improvement in validated outcome scores after 6 weeks and 1 year. Pooled data based on the Zurich Claudication Questionnaire of the RCTs were more in favor of IPD treatment compared with conservative treatment (pooled estimate 23.2, SD 18.5-27.8). Statistical heterogeneity after pooled data was low (I-squared 0.0, p = 0.930). Overall complication rate was 7%. CONCLUSION: As the evidence is relatively low and the costs are high, more thorough (cost-) effectiveness studies should be performed before worldwide implementation is introduced