Cardiometabolic, Inflammatory and Physical Inactivity Risk Factors in those with and without History of Pneumothorax

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A New Paradigm for Bodyweight Classification from the 2001-2006 National Health and Nutrition Examination Survey

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Non-equilibrium states of a photon cavity pumped by an atomic beam

We consider a beam of two-level randomly excited atoms that pass one-by-one through a one-mode cavity. We show that in the case of an ideal cavity, i.e. no leaking of photons from the cavity, the pumping by the beam leads to an unlimited increase in the photon number in the cavity. We derive an expression for the mean photon number for all times. Taking into account leaking of the cavity, we prove that the mean photon number in the cavity stabilizes in time. The limiting state of the cavity in this case exists and it is independent of the initial state. We calculate the characteristic functional of this non-quasi-free non-equilibrium state. We also calculate the energy flux in both the ideal and open cavity and the entropy production for the ideal cavity.Comment: Corrected energy production calculations and made some changes to ease the readin

Heart Rate Variability and Plank Exergaming with an Always-Superior Partner

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Us and them: Intergroup failures of empathy

People are often motivated to increase others' positive experiences and to alleviate others' suffering. These tendencies to care about and help one another form the foundation of human society. When the target is an outgroup member, however, people may have powerful motivations not to care about or help that “other.” In such cases, empathic responses are rare and fragile; it is easy to disrupt the chain from perception of suffering to motivation to alleviate the suffering to actual helping. We highlight recent interdisciplinary research demonstrating that outgroup members' suffering elicits dampened empathic responses as compared to ingroup members' suffering. We consider an alternative to empathy in the context of intergroup competition: schadenfreude—pleasure at others' pain. Finally, we review recent investigations of intergroup-conflict interventions that attempt to increase empathy for outgroups. We propose that researchers across the range of psychological sciences stand to gain a better understanding of the foundations of empathy by studying its limitations.Princeton University (Charlotte Elizabeth Procter Fellowship)Alliance of Civilizations (Media Fund)United States. Air Force Office of Scientific Research (grant #N000140910845

NKX2-5 regulates the expression of beta-catenin and GATA4 in ventricular myocytes.

BackgroundThe molecular pathway that controls cardiogenesis is temporally and spatially regulated by master transcriptional regulators such as NKX2-5, Isl1, MEF2C, GATA4, and beta-catenin. The interplay between these factors and their downstream targets are not completely understood. Here, we studied regulation of beta-catenin and GATA4 by NKX2-5 in human fetal cardiac myocytes.Methodology/principal findingsUsing antisense inhibition we disrupted the expression of NKX2-5 and studied changes in expression of cardiac-associated genes. Down-regulation of NKX2-5 resulted in increased beta-catenin while GATA4 was decreased. We demonstrated that this regulation was conferred by binding of NKX2-5 to specific elements (NKEs) in the promoter region of the beta-catenin and GATA4 genes. Using promoter-luciferase reporter assay combined with mutational analysis of the NKEs we demonstrated that the identified NKX2-5 binding sites were essential for the suppression of beta-catenin, and upregulation of GATA4 by NKX2-5.ConclusionsThis study suggests that NKX2-5 modulates the beta-catenin and GATA4 transcriptional activities in developing human cardiac myocytes

Relationship of Body Composition Variables and Performance Outcomes in Male Professional Soccer Players

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