1,584 research outputs found
Draft Genome Sequence of the Serratia rubidaea CIP 103234T Reference Strain, a Human-Opportunistic Pathogen.
We provide here the first genome sequence of a Serratia rubidaea isolate, a human-opportunistic pathogen. This reference sequence will permit a comparison of this species with others of the Serratia genus
Whole-Genome Sequence of a European Clone II and OXA-72-Producing Acinetobacter baumannii Strain from Serbia.
We report here the draft genome sequence of a carbapenem-resistant Acinetobacter baumannii strain isolated from a patient, a strain which previously stayed in Serbia. This isolate possessed the blaOXA-72 carbapenemase gene. The draft genome sequence consists of a total length of 3.91 Mbp, with an average G+C content of 38.8%
Lewis‐Acid‐Base Synthesis of [Se₃Cl₃]₂[SnCl₆] and [BMIm]₂[Ga₈As₆Cl₁₆O₁₄]
[Se3Cl3]2[SnCl6] (1) and [BMIm]2[Ga8As6Cl16O14] (2) are prepared by Lewis-acid-base reaction of SnCl2 with SeCl4 and As2O3 with GaCl3/[BMIm]Cl at room temperature and at 60 °C. 1 contains [ClSe−Se−SeCl2]+ cations with an Se3 unit and isolated octahedral [SnCl6]2− anions. The cation was yet only obtainable via Se0/Se4+ synproportionation in liquid SO2 with AsF5. The [Ga8As6Cl16O14]2− anion in 2 consists of two central edge-sharing GaO6 octahedra, surrounded by pseudo-tetrahedral AsO3 units and tetrahedral GaCl3O and GaCl2O2 units. Moreover, an almost planar central Ga4O4 ring surrounded by six GaAs2O3 rings is characteristic, which was not described before. The title compounds are characterized by X-ray diffraction based on single crystals and powders, infrared spectroscopy, thermogravimetry, and optical spectroscopy
Cervical cancer metastasis to the brain: A case report and review of literature
Background:
Intracranial metastasis from cervical cancer is a rare occurrence.
Methods:
In this study we describe a case of cervical cancer metastasis to the brain and perform an extensive review of literature from 1956 to 2016, to characterize clearly the clinical presentation, treatment options, molecular markers, targeted therapies, and survival of patients with this condition.
Results:
An elderly woman with history of cervical cancer in remission, presented 2 years later with a right temporo-parietal tumor, which was treated with surgery and subsequent stereotactic radiosurgery (SRS) to the resection cavity. She then returned 5 months later with a second solitary right lesion; she again underwent surgery and SRS to the resection cavity with no signs of recurrence 6 months later. According to the reviewed literature, the most common clinical presentation included females with median age of 48 years; presenting symptoms such as headache, weakness/hemiplegia/hemiparesis, seizure, and altered mental status (AMS)/confusion; multiple lesions mostly supratentorially located; poorly differentiated squamous cell carcinoma; and additional recurrences at other sites. The best approach to treatment is a multimodal plan, consisting of SRS or whole brain radiation therapy (WBRT) for solitary brain metastases followed by chemotherapy for systemic disease, surgery and WBRT for solitary brain lesions without systemic disease, and SRS or WBRT followed by chemotherapy for palliative care. The overall prognosis is poor with a mean and median survival time from diagnosis of brain metastasis of 7 and 4.6 months, respectively.
Conclusion:
Future efforts through large prospective randomized trials are warranted to better describe the clinical presentation and identify more effective treatment plans
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