227 research outputs found

    Farmers, seeds and varieties : supporting informal seed supply in Ethiopia

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    Ethiopia is characterized by an enormous diversity in agro-ecosystems, crops and varieties, with the informal seed systems dominant in seed supply for almost all crops. The book addresses strategies and approaches through which professionals can support informal seed supply, and links these with the conservation and use of the huge genetic resource base of crops and local varieties. The book looks at informal seed supply from a number of different angles, introduces key concepts and strategies, and presents case studies from Ethiopia and other countries. It deals with the technical aspects of, quality and availability of, and access to seed, and of supporting informal supply. It also deals with the role of farmers in the conservation and management of local crops and varieties, and the participation of farmers and communities in plant breeding and research. It takes a particular interest in the role of farmer organizations in seed supply, and how this role can be strengthened by developing community and small-scale seed enterprises. The aim of all the strategies, case studies and reflections on experiences presented in this book is to improve the availability of and access to quality seeds and varieties, thereby improving the livelihoods of small-scale farmers in Ethiopia and beyond

    Community Biodiversity Management: Promoting resilience and the conservation of plant genetic resources

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    This book is the first to set out a clear overview of CBM as a methodology for meeting socio-environmental changes. CBM is shown to be a key strategy that promotes community resilience, and contributes to the conservation of plant genetic resources. The authors present the underlying concepts and theories of CBM as well as its methodology and practices, and introduce case studies primarily from Brazil, Ethiopia, France, India, and Nepal. Contributors include farmers, leaders of farmers’ organizations, professionals from conservation and development organizations, students and scientists

    Post-translational modification of therapeutic peptides by NisB, the dehydratase of the lantibiotic nisin

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    Post-translationally introduced dehydroamino acids often play an important role in the activity and receptor specificity of biologically active peptides. In addition, a dehydroamino acid can be coupled to a cysteine to yield a cyclized peptide with increased biostability and resistance against proteolytic degradation and/or modified specificity. The lantibiotic nisin is an antimicrobial peptide produced by Lactococcus lactis. Its post-translational enzymatic modification involves NisB-mediated dehydration of serines and threonines and NisC-catalyzed coupling of cysteines to dehydroresidues, followed by NisT-mediated secretion. Here, we demonstrate that a L. lactis strain containing the nisBTC genes effectively dehydrates and secretes a wide range of medically relevant nonlantibiotic peptides among which variants of adrenocorticotropic hormone, vasopressin, an inhibitor of tripeptidyl peptidase II, enkephalin, luteinizing hormone-releasing hormone, angiotensin, and erythropoietin. For most of these peptides, ring formation was demonstrated. These data show that lantibiotic enzymes can be applied for the modification of peptides, thereby enabling the biotechnological production of dehydroresidue-containing and/or thioether-bridged therapeutic peptides with enhanced stability and/or modulated activities.</p

    Polariton condensation and lasing in optical microcavities - the decoherence driven crossover

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    We explore the behaviour of a system which consists of a photon mode dipole coupled to a medium of two-level oscillators in a microcavity in the presence of decoherence. We consider two types of decoherence processes which are analogous to magnetic and non-magnetic impurities in superconductors. We study different phases of this system as the decoherence strength and the excitation density is changed. For a low decoherence we obtain a polariton condensate with comparable excitonic and photonic parts at low densities and a BCS-like state with bigger photon component due to the fermionic phase space filling effect at high densities. In both cases there is a large gap in the density of states. As the decoherence is increased the gap is broadened and suppressed, resulting in a gapless condensate and finally a suppression of the coherence in a low density regime and a laser at high density limit. A crossover between these regimes is studied in a self-consistent way analogous to the Abrikosov and Gor'kov theory of gapless superconductivity.Comment: 17 pages, 8 figures, submitted to PR

    How Strong Do Global Commodity Prices Influence Domestic Food Prices in Developing Countries? A Global Price Transmission and Vulnerability Mapping Analysis

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    This paper analyzes the transmission from global commodity to domestic food prices for a large set of countries. First, a theoretical model is developed to explain price transmission for different trade regimes. Drawing from the competitive storage model under rational expectations, it is shown that domestic prices can respond instantaneously to global prices even if no trade takes place but future trade is expected. Using a global database on food prices, we construct national and international grain price indices. With an autoregressive distributed lag model, we empirically detect countries in which food prices are influenced by global commodity prices, including futures prices. Mapping transmission elasticities with the size of the population below the poverty line which spends typically a large share of its income on food, we are able to estimate the size of vulnerable population. Our empirical analysis reveals that 90 percent of the global poor (income below 1.25$/day) live in countries where domestic food prices respond to international prices - but the extent of transmission varies substantially. For 360 million poor people, international prices transmit to their country at rates of 30 percent or higher within three months

    Studies of non-conventional configuration closed electron drift thrusters

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    In this paper, we review recent results obtained for segmented electrode and cylindrical Hall thrusters. A low sputtering graphite segmented electrode, placed at the exit of the annular thruster, is shown to affect the plasma potential distribution in the ceramic channel. This effect appears to be correlated with an observed plume reduction compared to a conventional, nonsegmented thruster. In preliminary experiments a 3-cm thruster was operated in the 50-200 W power range. Two operating regimes, stable and oscillating, were observed and investigated

    Structure characterization of the central repetitive domain of high molecular weight gluten proteins. II. Characterization in solution and in the dry state

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    The structure of the central repetitive domain of high molecular weight (HMW) wheat gluten proteins was characterized in solution and in the dry state using HMW proteins Bx6 and Bx7 and a subcloned, bacterially expressed part of the repetitive domain of HMW Dx5. Model studies of the HMW consensus peptides PGQGQQ and GYYPTSPQQ formed the basis for the data analysis. In solution, the repetitive domain contained a continuous nonoverlapping series of both type I and type II β-turns at positions predicted from the model studies; type II β-turns occurred at QPGQ and QQGY sequences and type I β-turns at YPTS and SPQQ. The subcloned part of the HMW Dx5 repetitive domain sometimes migrated as two bands on SDS-PAGE; we present evidence that this may be caused by a single amino acid insertion that disturbs the regular structure of β-turns. The type I β-turns are lost when the protein is dried on a solid surface, probably by conversion to type II β-turns. The homogeneous type II β-turn distribution is compatible with the formation of a β-spiral structure, which provides the protein with elastic properties. The β-turns and thus the β-spiral are stabilized by hydrogen bonds within and between turns. Reformation of this hydrogen bonding network after, e.g., mechanical disruption may be important for the elastic properties of gluten proteins

    Demographic Change and the Labour Share of Income

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    Despite similar levels of per capita income, education, and technology the development of labour shares in OECD countries has displayed different patterns since 1960. The paper examines the role of demography in this regard. Employing an overlapping generations model we first examine the mechanisms through which demographic change can affect labour shares. Model simulations show that demographic effects on the labour share are larger in open than in closed economies. Empirical estimates, conducted using panel cointegration techniques for a panel of 18 OECD countries, provide strong support for demographic effects on the labour share. In line with the simulation results, we also find evidence that openness increases this impact
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