Oral microbiota and systemic disease

The oral cavity is has been resided by thousands of species of microorganisms, which remaining in different relationships. Disturbing the balance between microorganisms and host immunity can lead to the development of many serious local conditions, as well as changes in the organs placed away from the head and neck region. This article describes serious complications of local oral cavity infections like - exacerbation of chronic obstructive pulmonary, brain abscesses, infective endocarditis, diabetes mellitus, and even sepsis. The article also shows the potential connections between periodontal tissue inflammation and neurodegenerative disorders or cancer placed in distant organs. During treatment of periodontal patients, the physician should remember about the influence and risk of bacterial oral diseases

Oral Cavity Disorders Among Patients With Parkinson’S Disease - Case Reports

Parkinson's disease (PD) is a progressive, neurodegenerative ailment, caused by the loss of dopaminergic neurons in the specific area of a brain. Motor disability which is a symptom of PD, make maintaining the proper hygiene in the mouth difficult. Despite motor disorders, also cognitive dysfunctions can have a negative impact on the oral health of the patient, due to the lack of interest in the condition of the patient's oral cavity. Non-motor symptoms and even those associated with the oral cavity may be an indication for proper and early diagnosis of the patient. Disorders which occurs in the oral cavity during the sickness, are often neglected by patients and their caregivers. The role of the dentist in this situation is to make patients and their environment aware of the importance of the oral cavity - especially, due to the fact that newest studies suggest the association between ongoing systemic inflammation in the body, including periodontitis, and the development and progression of Parkinson's disease

Venovenous extracorporeal membrane oxygenation (VV ECMO) in community-acquired pneumonia caused by Klebsiella pneumoniae. What went wrong?

Despite the progress that has been made in the field of medicine, severe hypoxic respiratory failure due to pneumonia has significant mortality. The etiology of pneumonia can be very different but possible complications include sepsis and acute respiratory distress syndrome (ARDS), resulting in patient’s increased risk of death. Severe respiratory failure in the course of ARDS, which does not respond to conventional therapy, is an indication for the implementation of venovenous extracorporeal membrane oxygenation support (VV ECMO). However, even with the use of targeted antibiotic therapy and advanced methods of extracorporeal life support, successful outcomes are not achieved. The location of the site of infection and the administration of targeted antibiotic therapy seem obvious to the patient's prognosis. Antimicrobial therapy can only succeed if a few basic conditions are met. First of all, the right antibiotic should be used, given in the effective dose and as soon as possible after the onset of septic symptoms. In addition, the possibility of penetration of the active substance to the place affected by the inflammatory process also determines the probability of success of the therapy. This article presents a case report of Klebsiella pneumonia in a 38-year-old man and briefly discusses the challenges of modern medicine. In this case, the treatment was not successful, despite the known ethology, use of the targeted antibiotic therapy and advanced methods of extracorporeal life support. Further researches are needed to help improve treatment outcomes in this group, critically ill patients

Primary hepatocellular carcinoma in HBV infected patient - a case report

Hepatocellular carcinoma is primary neoplasm of the liver, which usually accompanies cirrhosis of this organ. This malignancy neoplasms commonly occurs all around the world. The frequency of morbidity on this disease is correlated with frequency of HBV and HCV infections in the population. That is caused due to the pathogenic effects of these viruses, among others on liver cells, affecting carcinogenesis. Appropriate and early treatment of infection reduces the chance of developing cancer. In our article we present the case, 63-years-old male, with primary hepatocellular carcinoma correlated with hepatitis B virus infection. Unfortunately, the neoplasm was diagnosed too late, and despite the comprehensive treatment introduced, the patient died

Infection with hepatitis C virus as a cause of nervous system disorders

Hepatitis C is a disease caused by hepatitis C virus (HCV), which prevalence may reach over 5% in some countries. Untreated infection may lead to death due to cirrhosis or hepatocellular carcinoma. Almost 80% of infected patients occurs as asymptomatic. Symptoms of hepatitis C may include jaundice, nausea, vomiting, fever or muscle and joint pains. Even half of the patients experience nervous system disorders, due to the affinity of some types of HCV to nerve cells. It is also estimated that up to 30% of patients with chronic hepatitis C will develop cirrhosis within 25-30 years. Currently, the vast majority of infected patients can be cured thanks to the introduction of direct-acting antivirals (DAAs)

Actinomycosis - forgotten disease as a diagnostic challenge

Łanowy Patrycja, Ślusarz Krystian, Dzindzio Jakub, Pyka Weronika, Bichalski Miłosz, Blaszkowszka Maria, Jaroszewicz Jerzy. Actinomycosis - forgotten disease as a diagnostic challenge. Journal of Education, Health and Sport. 2019;9(5):256-264. eISSN 2391-8306. DOI http://dx.doi.org/10.5281/zenodo.2901660 http://ojs.ukw.edu.pl/index.php/johs/article/view/6922 The journal has had 7 points in Ministry of Science and Higher Education parametric evaluation. Part B item 1223 (26/01/2017). 1223 Journal of Education, Health and Sport eISSN 2391-8306 7 © The Authors 2019; This article is published with open access at Licensee Open Journal Systems of Kazimierz Wielki University in Bydgoszcz, Poland Open Access. This article is distributed under the terms of the Creative Commons Attribution Noncommercial License which permits any noncommercial use, distribution, and reproduction in any medium, provided the original author (s) and source are credited. This is an open access article licensed under the terms of the Creative Commons Attribution Non commercial license Share alike. (http://creativecommons.org/licenses/by-nc-sa/4.0/) which permits unrestricted, non commercial use, distribution and reproduction in any medium, provided the work is properly cited. The authors declare that there is no conflict of interests regarding the publication of this paper. Received: 28.04.2019. Revised: 28.04.2019. Accepted: 18.05.2019. Actinomycosis - forgotten disease as a diagnostic challenge Patrycja Łanowy1, Krystian Ślusarz1, Jakub Dzindzio1, Weronika Pyka1, Miłosz Bichalski1, Maria Blaszkowszka1, Jerzy Jaroszewicz1*, ¹Department of Infectious Diseases and Hepatology in Bytom, Medical University of Silesia, Poland E-mail addresses: [email protected], [email protected], [email protected], [email protected], [email protected], [email protected], 1*Coressponding author: [email protected] ABSTRACT Actinomycosis is neglected, uncommon disease caused by bacteria. The greatest difficulty in correct and early diagnostics of actinomycosis is the fact that it often mimics other conditions. The difficulties in diagnostic of actinomycosis result in misdiagnosis, lengthening the patient's treatment time, unnecessary surgical treatment and sometimes dangerous complications. Aim of the article: The aim of the article is to familiarize readers with the rarest conditions that have been mistaken for actinomycosis. KEYWORDS: actinomycosis, diagnostic difficulties, misdiagnosis, malignancy mimicking tumo

The role of essential oils in oral hygiene - a review of the literature

Due to increasing of resistance of the microorganisms which causes periodontitis, mucositis - essential oils - source known from antiquity, may be helpful. Extracted from plants essential oils (EO of the selected plants) - contain in selected oils, can reduce the amount of pathogens in the mouth and help the action of antibiotics and other active components used in the prevention and the treatment of oral diseases. Essential oils are widely used: to reduce the formation of the plaque which is a biofilm produced by bacteria on the surface of hard tooth tissues. Dental plaque contributes to the development of periodontitis and tooth decay. The article contains an overview of the most popular essential oils and analysis of the results of the long-term studies on the effectiveness of mouthwashes containing essential oils. Aim of the article: Determination of the range of use the essential oils in various fields of dentistry and determination the actual effectiveness of essential oils in reducing plaque based on available researches