Effects of coenzyme Q10 on the oxidative stress and heat shock proteins in exercise rats

OBJECTIVE: In this reserach,it has been tried to observe the effects of coenzym Q10 on oxcidative stress, heat shock proteins and biochemistry serum parameters in rats applied exercise. METHODS: It has been used totally 42, aged eight weeks, Wistar Albino Rats which is grouped of 6 (control,coenzym Q10,exercise,exercise+coenzym Q10,acute exercise ve acute exercise+coenzym Q10) each of them contains 7 rats. In the begining, the rats are made to run 10 m/min and at the end of two weeks, the thirty minutes running process being %0 slope and 30 m/min was implemented in a controlled increase. The rats have been tested to run 5 days a week along six weeks after applying coenzym Q10 on a diet and on the last day, acute exercise process (running on the band untill tired) has been applied. Datas have been evaluated by using ANOVA process in the IBM SPSS (version 22) packaged software.The comparison among groups have been analized with the help of Turkey Post Hoc Test.The datas have been given as group avarage and standart error of mean (SEM). Statistical significance has been defined as meaningfull for the ones whose probablity values are under the point of 0.05. RESULTS AND CONCLUSIONS: Finally, it’s been seen that there is no effect of coenzym Q10 on the functions of liver or kidney and coenzym Q10 doesn’t effect glucose on cardiometabolic biochemical parameters.In adddition to these, it decreases cholesterol and triglyceride.While acute exercise increases oxcidative stress,chronic exercise decreases oxcidative stress by reducing the level of lipid peroxydation. It has shown this effect by means of regulating heat shock proteins.Also, it has shown the effect of consumption of coenzym Q10 by reducing heat shock protein.Moreover, it has been observed that chronic exercise and coenzym Q10 decreases oxcidative stress by working synergisticallly

Low oxygen saturation following total correction in a patient with tetralogy of fallot and persistant left superior caval vein - How did we diagnose and manage?

Association of tetralogy of Fallot (TOF) with the other intracardiac pathologies such as atrial septal defect (ASD), atrioventricular canal defect or persistent left superior vena cava (PLSVC), absent pulmonary valve are well known pathologies. The associated pathologies require specifi c attention during surgical treatment. In this manuscript, we present management of a four-month-old girl who was diagnosed with TOF and PLSVC but the diagnosis of unroofed coronary sinus was missed in her. Association of unroofed coronary sinus with TOF is a very rare variant of TOF pathology.Souvislost mezi Fallotovou tetralogií (tetralogy of Fallot, TOF) a jinými intrakardiálními patologiemi, jako jsou defekt septa síní (atrial septal defect, ASD), defekt síňokomorového kanálu nebo perzistentní levostranná horní dutá žíla (persistent left superior vena cava, PLSVC) i absence plicní chlopně, je dobře známa. Během chirurgického výkonu vyžadují přidružená onemocnění obzvláštní pozornost. V tomto článku popisujeme léčbu čtyřměsíční dívky s diagnózou TOF a PLSVC, u níž však byl přehlédnut nezastřešený koronární sinus. Nezastřešený koronární sinus se vyskytuje současně s TOF velmi vzácně

Endovascular Stent Grafting for Aortic Arch Aneurysm in Aortoiliac Occlusive Disease following Aortic Arch Debranching and Aortobifemoral Reconstruction

Treatment of thoracic aortic aneurysms constitutes high mortality and morbidity rates despite improvements in surgery, anesthesia, and technology. Endovascular stent grafting may be an alternative therapy with lower risks when compared with conventional techniques. However, sometimes the branches of the aortic arch may require transport to the proximal segments prior to successful thoracic aortic endovascular stent grafting. Atherosclerosis is accounted among the etiology of both aneurysms and occlusive diseases that can coexist in the same patient. In these situations stent grafting may even be more complicated. In this report, we present the treatment of a 92-year-old patient with aortic arch aneurysm and proximal descending aortic aneurysm. For successful thoracic endovascular stent grafting, the patient needed an alternative route other than the native femoral and iliac arteries for the deployment of the stent graft. In addition, debranching of left carotid and subclavian arteries from the aortic arch was also required for successful exclusion of the thoracic aneurysm

THE EFFECTIVENESS OF PREGNANCY REHABILITATION: EFFECTS ON LOW BACK PAIN AND CALF CRAMPS DURING PREGNANCY AND PREGNANCY OUTCOME

Objective: Our purpose was to investigate the effects of our pregnancy rehabilitation program on pregnancy outcome, experience of labor and delivery of the mothers, low back pain and leg cramps experienced during pregnancy