141 research outputs found
The Impact of Integration on Application Success and Customer Satisfaction in Mobile Device Platforms
Digital software platforms allow third parties to develop applications and thus extend their functionality. Platform owners provide platform boundary resources that allow for application development. For developers, plat- form integration, understood as the employment of plat- form resources, helps to realize application functionality effectively. Simultaneously, it requires integration effort and increases dependencies. Developers are interested to know whether integration contributes to success in hyper- competitive platform settings. While aspects of platform participation have been studied, research on a compre- hensive notion of integration and related implications are missing. By proposing a platform integration model, this study supports a better understanding of integration. Con- cerning dynamics related to integration, effects were tested using information from over 82,000 Apple AppStore applications. Regression model analysis reveals that application success and customer satisfaction is positively influenced by platform integration. To achieve superior results, developers should address multiple aspects of integration, such as devices, data, the operating system, the marketplace as well as other applications, and provide updates. Finally, the study highlights the importance for all platform participants and their possibilities to employ integration as a strategic instrument
Astrometry with the Hubble Space Telescope: Trigonometric Parallaxes of Selected Hyads
We present absolute parallaxes and proper motions for seven members of the
Hyades open cluster, pre-selected to lie in the core of the cluster. Our data
come from archival astrometric data from FGS 3, and newer data for 3 Hyads from
FGS 1R, both white-light interferometers on the Hubble Space Telescope (HST).
We obtain member parallaxes from six individual Fine Guidance Sensor (FGS)
fields and use the field containing van Altena 622 and van Altena 627 (= HIP
21138) as an example. Proper motions, spectral classifications and VJHK
photometry of the stars comprising the astrometric refer- ence frames provide
spectrophotometric estimates of reference star absolute parallaxes. Introducing
these into our model as observations with error, we determine absolute
parallaxes for each Hyad. The parallax of vA 627 is significantly improved by
including a perturbation orbit for this previously known spectroscopic binary,
now an astrometric binary. Compared to our original (1997) determina- tions, a
combination of new data, updated calibration, and improved analysis lowered the
individual parallax errors by an average factor of 4.5. Comparing parallaxes of
the four stars contained in the Hipparcos catalog, we obtain an average factor
of 11 times improvement with the HST . With these new results, we also have
better agreement with Hipparcos for the four stars in common. These new
parallaxes provide an average distance for these seven members, = 47.5
pc, for the core a \pm 1 - {\sigma} dispersion depth of 3.6 pc, and a minimum
depth from individual components of 16.0 \pm 0.9 pc. Absolute magnitudes for
each member are compared to established main sequences, with excellent
agreement. We obtain a weighted average distance modulus for the core of the
Hyades of m-M=3.376 \pm 0.01, a value close to the previous Hipparcos values,
m-M=3.33\pm 0.02.Comment: 21 pages, 7 figures, Astronomical Journal, accepted 2011-3-
Enterprise-Level IS Research â Need, Conceptualization, Exemplary Knowledge Contributions and Future Opportunities
E-Mail Tracking in Online Marketing - Methods, Detection, and Usage
E-Mail tracking uses personalized links and pictures for gathering information on user behavior, for example, where, when, on what kind of device, and how often an e-mail has been read. This information can be very useful for marketing purposes. On the other hand, privacy and security requirements of customers could be violated by tracking. This paper examines how e-mail tracking works, how it can be detected automatically, and to what extent it is used in German e-commerce. We develop a detection model and software tool in order to collect and analyze more than 600 newsletter e-mails from companies of several different industries. The results show that the usage of e-mail tracking in Germany is prevalent but also varies depending on the industry
Web Tracking - A Literature Review on the State of Research
Web tracking seems to become ubiquitous in online business and leads to increased privacy concerns of users. This paper provides an overview over the current state of the art of web-tracking research, aiming to reveal the relevance and methodologies of this research area and creates a foundation for future work. In particular, this study addresses the following research questions: What methods are followed? What results have been achieved so far? What are potential future research areas? For these goals, a structured literature review based upon an established methodological framework is conducted. The identified articles are investigated with respect to the applied research methodologies and the aspects of web tracking they emphasize
E-Mail Tracking: Status Quo and Novel Countermeasures
E-mail advertisement, as one instrument in the marketing mix, allows companies to collect fine-grained behavioural data about individual usersâ e-mail reading habits realised through sophisticated tracking mechanisms. Such tracking can be harmful for user privacy and security. This problem is especially severe since e-mail tracking techniques gather data without user consent. Striving to increase privacy and security in e-mail communication, the paper makes three contributions. First, a large database of newsletter e-mails is developed. This data facilitates investigating the prevalence of e-mail tracking among 300 global enterprises from Germany, the United Kingdom and the United States. Second, countermeasures are developed for automatically identifying and blocking e-mail tracking mechanisms without impeding the user experience. The approach consists of identifying important tracking descriptors and creating a neural network-based detection model. Last, the effectiveness of the proposed approach is established by means of empirical experimentation. The results suggest a classification accuracy of 99.99%
Digitalisation and Enterprise Knowledge (net)Working
Social media and emerging mobile technologies have forever changed the landscape of human interaction. Furthermore, they already play a pivotal role also in enterprises as a part of the organisational Knowledge Management System. Almost all large organisations have already implemented at least one Enterprise Social Media tool since they enable collaboration, provide easy access to information, and are available at reasonable costs. The effects of the decoupling of the real and the virtual world (as a result of Social Media use) on the construct knowledge and on knowledge management are still not sufficiently investigated. Against this background, the paper presents an exploratory approach of the development of a specific morphological tableau as an instrument for the analysis of employeesâ behavior in context of knowledge management related ESM use. Furthermore, the application of the tableau is exemplary illustrated and further research steps are explained
Efficient Task Realizations in Networked Production Infrastructures
As Industry 4.0 infrastructures are seen as highly evolutionary environment with volatile, and time-dependent workloads for analytical tasks, particularly the optimal dimensioning of IT hardware is a challenge for decision makers because the digital processing of these tasks can be decoupled from their physical place of origin. Flexible architecture models to allocate tasks efficiently with regard to multi-facet aspects and a predefined set of local systems and external cloud services have been proven in small example scenarios. This paper provides a benchmark of existing task realization strategies, composed of (1) task distribution and (2) task prioritization in a real-world scenario simulation. It identifies heuristics as superior strategies
A defect in molybdenum cofactor binding causes an attenuated form of sulfite oxidase deficiency
Isolated sulfite oxidase deficiency (ISOD) is a rare recessive and infantile lethal metabolic disorder, which is caused by functional loss of sulfite oxidase (SO) due to mutations of the SUOX gene. SO is a mitochondrially localized molybdenum cofactor (Moco)- and heme-dependent enzyme, which catalyzes the vital oxidation of toxic sulfite to sulfate. Accumulation of sulfite and sulfite-related metabolites such as S-sulfocysteine (SSC) are drivers of severe neurodegeneration leading to early childhood death in the majority of ISOD patients. Full functionality of SO is dependent on correct insertion of the heme cofactor and Moco, which is controlled by a highly orchestrated maturation process. This maturation involves the translation in the cytosol, import into the intermembrane space (IMS) of mitochondria, cleavage of the mitochondrial targeting sequence, and insertion of both cofactors. Moco insertion has proven as the crucial step in this maturation process, which enables the correct folding of the homodimer and traps SO in the IMS. Here, we report on a novel ISOD patient presented at 17 months of age carrying the homozygous mutation NM_001032386.2 (SUOX):c.1097G > A, which results in the expression of SO variant R366H. Our studies show that histidine substitution of Arg366, which is involved in coordination of the Moco-phosphate, causes a severe reduction in Moco insertion efficacy in vitro and in vivo. Expression of R366H in HEK SUOX-/- cells mimics the phenotype of patient's fibroblasts, representing a loss of SO expression and specific activity. Our studies disclose a general paradigm for a kinetic defect in Moco insertion into SO caused by residues involved in Moco coordination resulting in the case of R366H in an attenuated form of ISO
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