Osteogenesis Imperfecta (Type IV) with Dental Findings in Siblings

Osteogenesis imperfecta (OI) is a hereditary disorder characterized by increased tendency for bone fractures due to high fragility. The clinical and radiological features of OI manifest in different age groups, although the disease is congenital in nature. Besides bone fragility, features like laxity of the ligaments, blue sclera, growth retardation, and scoliosis are also observed. In severe cases, respiratory distress and death have been reported. The most important oral finding in OI is the presence of yellowish-brown-coloured brittle teeth characteristic of dentinogenesis imperfecta. Genetic factors play a very important role in the pathogenesis of OI either as a dominant or recessive factor. When a child has OI, there is a 25% chance of the sibling to have the same disorder. We report two cases of OI in siblings born to parents with a history of consanguineous marriage. The clinical and radiological features of the two cases are described in detail

Anterior maksillada süpernumerer dişin inverse erüpsiyonu: Nadir bir olgu raporu

Literatürde hem maksillada hem de mandibulada inverse diş erüpsiyonları bildirilmiştir ve bunların çoğu inverse gömülü üçüncü büyük azı dişleri ve küçük azı dişleridir. Ancak, ağız içi inverse diş erüpsiyonu günümüze kadar çok az durumda bildirilmiştir. Biz burada maksillada merkezi ve yan kesici dişler arasındaki inverse süpernumerer dişle ilgili benzersiz bir olguyu bildirmekteyiz

Walking Molar – A radiographic Presentation

Dilaceration is the result of a developmental anomaly in which there has been an abrupt change in the axial inclination between the crown and the root of a tooth. It is seen involving both the permanent and primary dentitions. Root canal curvatures may be apical, gradual, sickle-shaped, severe-moderate-straight curve, bayonet / S-shaped curve and dilacerated curve. Curved root canals exhibit great difficulty in cleaning, shaping and obturation of the root canal system. This mandates routine periapical radiographs which aid the clinician in assessing these morphological variations in the root canal system. This article highlights a rare presentation of dilacerated distal root of left mandibular first molar resembling radiographically as walking molar in 17-year-male patient

Xeroderma Pigmentosum: Man Deprived of His Right to Light

Xeroderma pigmentosum (XP) is a hereditary autosomal recessive disorder characterized by photo hypersensitivity of sun exposed tissues and subsequent several-fold increased risk for malignant changes resulting from impaired ability to repair UV-induced DNA damage. Estimated incidences vary from 1 in 20,000 in Japan to 1 in 250,000 in the USA, and approximately 2.3 per million live births in Western Europe. Diagnosis is made clinically by the presence of unusual sunburns or lentiginosis or onset of cancers at an early age. It is confirmed by cellular tests for defective DNA repair. Although there is no cure for XP as of now, skin problems can be ameliorated with the use of sunscreens, sun avoidance methods, and recurrent tumor excisions. Oral isotretinoin and topical application of 5-fluorouracil to treat actinic keratoses are other therapeutic options. T4N5 and photolyase liposomal lotions are innovations in the therapy of XP. Genetic counselling implicating the effect of consanguineous marriages should be considered in the management of XP patients

Can saliva offer an advantage in monitoring of diabetes mellitus?: a case control study

Objectives: Diabetes Mellitus is emerging as a major health problem over these years. Present method of blood glucose monitoring by venepuncture is invasive leading to reduced patient compliance and thereby ineffective judicious monitoring. The need of the hour is to direct research in the direction of establishing painless and more acceptable blood glucose analysis method.The objective of the study is to conduct a comparative analysis of the concentrations of salivary glucose and blood glucose in type 2 diabetes mellitus patients. Study Design: This study assessed glucose levels using the glucose oxidase method in blood and unstimulated sali - va in 90 subjects who were divided into 3 equal groups of controlled type 2 diabetes, uncontrolled type 2 diabetes and those without diabetes. Statistical analysis was carried out using one way ANOVA, Post hoc Tukeys tests and Pearson's correlation coefficient test. Results: Salivary glucose levels were significantly higher in patients with diabetes than controls. There was a signi - ficant positive correlation between salivary and plasma glucose levels in patients with diabetes. Conclusions: Glucose concentration in saliva is higher in diabetics but hyperglycemia does not influence salivary glucose levels. Further clarification is required to claim the diagnostic potentials of saliva in diabetes

Lateral Periodontal Cyst: A Report of Two Cases with Varying Clinico-Radiological Features

Lateral periodontal cyst (LPC) is an uncommon type of odontogenic cyst of developmental origin that typically occurs laterally on the root surface of a tooth, representing 0.8% - 2% of cysts in the jaws. They are frequently located in the mandibular premolar area followed by the anterior region of the maxilla. It is usually asymptomatic and is discovered on a routine radiograph. The involved teeth are usually vital. Although the occurrence of lateral periodontal cyst is rare, the precision of its diagnosis is necessary so that the correct treatment can be established. The purpose of this article is to report two cases of lateral periodontal cyst, one presenting with typical clinical features while other having contrasting features and to review the relevant literature which describes the clinical, radiological and histopathological features of lateral periodontal cysts. [J Interdiscipl Histopathol 2012; 1(1.000): 41-44

Radiologic features of intraosseous hemangioma: A diagnostic challenge

Intraosseous vascular lesions are rare conditions, comprising only 0.5% to 1% of all intraosseous tumors. They present with variable and atypical radiographic appearances. Because of this variation, no pathognomonic sign exists that can be used to make a definite clinical diagnosis of these tumors. But, early diagnosis of central hemangioma is essential for preventing uncontrollable hemorrhage and even death during biopsy or surgery. The purpose of this article is to stress on the importance of radiology in the timely diagnosis of such lesions, which can prevent the disaster not only to the patient but also to oral surgeon in legal and professional aspects