Organizing product-oriented environmental management from a resource-based perspective

More and more the biophysical environment is being acknowledged as a critical business concern, while the environmental performance of products is becoming increasingly important to all parts of the product chain. Systematical attempts to decrease the environmental impact of a product throughout its life cycle could contribute to a firm's sustainable development potential, since product-oriented environmental management (POEM) addresses different themes of sustainable industrial development. POEM is defined as an approach to organizing a firm in such a way that improving the environmental performance of its products and processes becomes an integral part of both operations and strategy

Social Investment, Employment Outcomes and Policy and Institutional Complementarities: A Comparative Analysis across 26 OECD countries

Social investment has become a widely debated topic in the comparative welfare state literature. To date, there are, however, only a couple of systematic comparative empirical analyses that focus on the employment outcomes associated with social investment. This study contributes to the social investment literature by empirically analysing the extent to which variation in employment outcomes across 26 OECD countries over the period 1990-2010 can be explained by effort on five social investment policies using time-series cross-sectional analyses. Apart from focusing on employment rates, we additionally explore associations with qualitative aspects of the employment outcomes relying on novel indicators. The analyses account for theoretically relevant confounding variables that were omitted in existing studies, notably labour market institutions. We find robust evidence for a positive association between effort on active labour market policies and employment rates. For other policies we obtain mixed results, dependent on the employment outcome being studied. Subsequently, we explore the role of policy and institutional complementarities in the assessment of the employment effects of social investment policies. We show how social investment policies interact and how their effect is moderated by effort on other policies. Additionally, our analysis shows that the complementarity of social investment policies varies across welfare state regimes. Finally, explorative analyses suggest that there are positive synergies between more and better jobs, which could in part be attributable to effort on social investment

Social Investment, Employment Outcomes and Policy and Institutional Complementarities: A Comparative Analysis across 26 OECD countries

Social investment has become a widely debated topic in the comparative welfare state literature. To date, there are, however, only a couple of systematic comparative empirical analyses that focus on the employment outcomes associated with social investment. This study contributes to the social investment literature by empirically analysing the extent to which variation in employment outcomes across 26 OECD countries over the period 1990-2010 can be explained by effort on five social investment policies using time-series cross-sectional analyses. Apart from focusing on employment rates, we additionally explore associations with qualitative aspects of the employment outcomes relying on novel indicators. The analyses account for theoretically relevant confounding variables that were omitted in existing studies, notably labour market institutions. We find robust evidence for a positive association between effort on active labour market policies and employment rates. For other policies we obtain mixed results, dependent on the employment outcome being studied. Subsequently, we explore the role of policy and institutional complementarities in the assessment of the employment effects of social investment policies. We show how social investment policies interact and how their effect is moderated by effort on other policies. Additionally, our analysis shows that the complementarity of social investment policies varies across welfare state regimes. Finally, explorative analyses suggest that there are positive synergies between more and better jobs, which could in part be attributable to effort on social investment

Short-Term Clinical Outcomes of Single Versus Dual Antiplatelet Therapy after Infrainguinal Endovascular Treatment for Peripheral Arterial Disease

After infrainguinal endovascular treatment for peripheral arterial disease (PAD), it is uncertain whether single antiplatelet therapy (SAPT) or dual antiplatelet therapy (DAPT) should be preferred. This study investigated major adverse limb events (MALE) and major adverse cardiovascular events (MACE) between patients receiving SAPT and DAPT. Patient data from three centers in the Netherlands were retrospectively collected and analyzed. All patients treated for PAD by endovascular revascularization of the superficial femoral, popliteal, or below-the-knee (BTK) arteries and who were prescribed acetylsalicylic acid or clopidogrel, were included. End points were 1-, 3-, and 12-month MALE and MACE, and bleeding complications. In total, 237 patients (258 limbs treated) were included, with 149 patients receiving SAPT (63%) and 88 DAPT (37%). No significant differences were found after univariate and multivariate analyses between SAPT and DAPT on 1-, 3-, and 12-month MALE and MACE, or bleeding outcomes. Subgroup analyses of patients with BTK treatment showed a significantly lower 12-month MALE rate when treated with DAPT (hazard ratio 0.33; 95% confidence interval 0.12-0.95; p = 0.04). In conclusion, although patient numbers were small, no differences were found between SAPT and DAPT regarding MALE, MACE, or bleeding complications. DAPT should, however, be considered over SAPT for the subgroup of patients with below-the-knee endovascular treatment

The changing landscape of conservation science funding in the United States

To understand the changing role of funding sources in shaping conservation science in the United States, we analyzed acknowledgments from published studies, trends in research funding, and survey responses from conservation scientists. Although the U.S. federal government was the most frequently acknowledged source of support overall, U.S. foundations and NGOs were the predominant sources for tropical and socioeconomic research. Acknowledgments of foundation support for conservation research increased over the last two decades, while recognition of federal funds declined. Concordant trends in funding and acknowledgments indicated a changing landscape for conservation science, in which federal support has not kept pace with the growth in conservation research efforts or needs. Survey responses from conservation scientists about their funding sources were consistent with acknowledgment data, and most (64%) indicated that shifts in funding sources and amounts affected the type of research they conduct. Ongoing changes in the funding landscape shape the direction of conservation research and may make conservation science more vulnerable to economic recessions

First Experience With The GoBack-Catheter For Successful Crossing of Complex Chronic Total Occlusions in Lower Limb Arteries

Purpose: To evaluate the use of the GoBack-catheter (Upstream Peripheral Technologies) in complex revascularizations in lower limb arteries. Materials and Methods: In this retrospective single-center study, the results of the first 100 consecutive patients including 101 limb-revascularizations, performed between May 2018 and July 2020 with the study device, were analyzed. In all cases, guidewire-crossing failed, and all lesions were chronic total occlusions (CTO), either de novo, reocclusions, or in-stent reocclusions. Successful crossing was defined as passing the CTO using the study device. Patency at discharge and after 30 days was defined as less than 50% restenosis on duplex sonography, without target lesion revascularization. Results: Median lesion length was 24 cm and 38 patients (37.6%) had a calcium grading according to the peripheral arterial calcium scoring system (PACSS) of 4 or 5. In 20.8% of patients, an occluded stent was treated. CTOs involved the femoropopliteal segment in 91.1%, iliac arteries in 5.9%, and tibial arteries in 7.9%. The GoBackcatheter was employed for entering into or crossing through parts or the full length of a CTO or an occluded stent as well as for re-entering into the true lumen after subintimal crossing. The device was used via contralateral and ipsilateral antegrade as well as retrograde access with an overall technical success rate of 92.1%. In 3 patients minor bleeding occurred at the crossing or re-entry site, which were managed conservatively. Thirty-day adverse limb events comprised minor amputations in 4 patients (4.0%), 1 major amputation (1.0%), and reocclusions in 7 limbs (6.9%). Conclusion: The new GoBack-catheter offers versatile endovascular applicability for complex CTO recanalization in a broad range of peripheral vascular interventions with a high technical success and low complication rate

Draining sterile fluid collections in acute pancreatitis? Primum non nocere!

Contains fulltext : 95829.pdf (publisher's version ) (Open Access

Minimally invasive and endoscopic versus open necrosectomy for necrotising pancreatitis: a pooled analysis of individual data for 1980 patients

https://www.ncbi.nlm.nih.gov/pubmed/2877488