80 research outputs found

    Technologies for aging gracefully

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    Medien der Soziologie

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    Medien vermitteln die Möglichkeit von Alternativen. Texte müssen sich gegenüber Texten, aber auch gegenüber Bildern und Formeln behaupten. Und dasselbe gilt für Bilder, Formeln und das Gespräch. Es geht jeweils um die Phrasierung von Kommunikation und die Formierung von Einbildungskraft. Michael Guggenheim diskutiert Texte im Verhältnis zu Bildern, Zeichnungen und Fotografien. Moritz Klenk setzt Texte in ein Verhältnis zu Podcasts. Tobias Schlechtriemen untersucht Netzwerke als Beispiel jener bildlichen Vorstellungen, an denen sich die soziologische Einbildungskraft orientiert. Und Ulrik Brandes schaut sich genauer an, welche theoretischen Annahmen die Netzwerkforschung befähigen, Daten zu konstruieren. Media convey the possibility of alternatives. Texts have to stand up to texts, but also to images and formulas. And the same is true for images, formulas, and conversation. In each case, it is about the phrasing of communication and the formation of imagination. Michael Guggenheim discusses texts in relation to images, drawings, and photographs. Moritz Klenk places texts in relation to podcasts. Tobias Schlechtriemen examines networks as an example of those almost visual imaginaries to which the sociological imagination is oriented. And Ulrik Brandes takes a closer look at which theoretical assumptions enable network research to construct data

    Development of Cytotoxic GW7604-Zeise’s Salt Conjugates as Multitarget Compounds with Selectivity for Estrogen Receptor- Positive Tumor Cells

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    (E/Z)-3-(4-((E)-1-(4-Hydroxyphenyl)-2-phenylbut-1-enyl)phenyl)acrylic acid (GW7604) as a carrier was esterified with alkenols of various lengths and coordinated through the ethylene moiety to PtCl3, similar to Zeise’s salt (K[PtCl3(C2H4)]). The resulting GW7604-Alk-PtCl3 complexes (Alk = Prop, But, Pent, Hex) degraded in aqueous solution only by exchange of the chlorido ligands. For example, GW7604-Pent-PtCl3 coordinated the amino acid alanine in the cell culture medium, bound the isolated nucleotide 5′-GMP, and interacted with the DNA (empty plasmid pSport1). It accumulated in estrogen receptor (ER)-positive MCF-7 cells primarily via cytosolic vesicles, while it was only marginally taken up in ER-negative SKBr3 cells. Accordingly, GW7604-Pent-PtCl3 and related complexes were inactive in SKBr3 cells. GW7604-Pent-PtCl3 showed high affinity to ERα and ERβ without mediating agonistic or ER downregulating properties. GW7604-Alk ligands also increased the cyclooxygenase (COX)-2 inhibitory potency of the complexes. In contrast to Zeise’s salt, the GW7604-Alk-PtCl3 complexes inhibited COX-1 and COX-2 to the same extent

    Varieties of Capitalism and the Learning Firm: Contemporary Developments in EU and German Company Law - A Comment on the Strine-Bainbridge Debate About Shared Values of Corporate Management and Labor

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    Research in corporate governance and in labour law has been characterized by a disjuncture in the way that scholars in each field are addressing organizational questions related to the business enterprise. While labour has eventually begun to shift perspectives from aspirations to direct employee involvement in firm management, as has been the case in Germany, to a combination of \u27exit\u27 and \u27voice\u27 strategies involving pension fund management and securities litigation, it remains to be seen whether this new stream will unfold as a viable challenge to an otherwise exclusionary shareholder value paradigm. At the same time, recent suggestions made by Delaware Chancery Court Vice Chancellor Strine, to dare think about potentially shared commitments between management and labor - and UCLA\u27s Stephen Bainbridge\u27s response - underline the viability - and, the contestedness - of attempts at moving the corporate governance debate beyond the confines of corporate law proper. While such a wider view had already famously been encouraged by Dean Clarke in his 1986 treatise on Corporate Law (p. 32), mainstream corporate law does not seem to have endorsed this perspective. This paper takes the questionable divide between management and labor within the framework of a limiting corporate governance concept as starting point to explore the institutional dynamics of the corporation, hereby building on the theory of the innovative enterprise, as developed by management theorists Mary O\u27Sullivan and William Lazonick. Largely due to the sustained distance between corporate and labour law scholars, neither group has effectively addressed their common blind spot: a better understanding of the business enterprise itself. In midst of an unceasing flow of affirmations of the finance paradigm of the corporation on the one hand and \u27voice\u27 strategies by labour on the other, it seems to fall to management theorists to draw lessons from the continuing co-existence of different forms of market organization, in which companies appear to thrive. Exploring the conundrum of \u27risky\u27 business decisions within the firm, management theorists have been arguing for the need to adopt a more sophisticated organizational perspective on companies operating on locally, regionally and transnationally shaped, often highly volatile market segments. Research by comparative political economists has revealed a high degree of connectivity between corporate governance and economic performance without, however, arriving at such favourable results only for shareholder value regimes. Such findings support the view that corporate governance regimes are embedded in differently shaped regulatory frameworks, characterized by distinct institutions, both formal and informal, and enforcement processes. As a result of these findings, arguments to disassociate issues of corporate governance from those of the firm\u27s (social) responsibility [CSR] have been losing ground. Instead, CSR can be taken to be an essential part of understanding a particular business enterprise. It is the merging of a comparative political economy perspective on the corporation with one on the organizational features, structures and processes of the corporation, which can help us better understand the distribution of power and knowledge within the \u27learning firm\u27

    TO ERADICATION OF VOLTAGE SAG AND HARMONICS IN DISTRIBUTION SYSTEM USING DVR WITH CAPACITOR COMPENSATION SCHEME

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    Power Quality (PQ) is that the most vital perspectives on transmission and distribution ranges. The availability of high-grade electric powered offerings wished for the customers illustrates this idea. The voltage sag and swell square degree the most not unusual PQ problems that in particular rise up in the distribution systems because of the truth that it's going to cause tool tripping, failure of stress systems, closure for home and business instrumentality. The Dynamic Voltage Restorer (DVR) associated nonparallel has amazing dynamic talents and is a flexible solution for PQ troubles. Ultra-capacitors (UCAP) have quality developments like excessive strength and espresso electricity density important for the mitigation of voltage sag and swell. This paper offers AN extended DVR topology capable of handing over deep, prolonged mitigation for power terrific troubles. Within the planned DVR, UCAP is employed as strength storage because it offers immoderate electricity in a totally short c software language length of it gradual. The DVR is protected into Ultra capacitor via a bifacial DC-DC converter which facilitates in supplying a rigid dc-link voltage and conjointly enables in compensating transient voltage sag and voltage swell. PI Controller is hired in DVR for electricity exceptional improvement. The simulation model for the proposed device has been superior in MATLAB and therefore the performance over famous DVR is legitimate with the effects obtained

    Reading Together as a Leisure Activity: implications for e-reading

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    Abstract. Reading from devices such as Kindles, Nooks, and tablets (“ereaders”) is an increasingly common practice. A primary reason users purchase e-readers is to read for pleasure, as opposed to reading for work or school purposes. With paper, people sometimes read together from a single book (e.g., reading a bedtime story with a child) – a practice we call partnered reading. This practice, and the goals of e-reading for pleasure more generally, remain underexplored in the HCI literature. This paper contributes findings from a deployment study wherein participants used an e-reader application to read with a partner. These findings (a) provide descriptive accounts of how people use e-readers to read together, and (b) identify opportunities to improve the design of e-readers to support partnered e-reading for pleasure
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