250 research outputs found
PILOT: a balloon-borne experiment to measure the polarized FIR emission of dust grains in the interstellar medium
Future cosmology space missions will concentrate on measuring the
polarization of the Cosmic Microwave Background, which potentially carries
invaluable information about the earliest phases of the evolution of our
universe. Such ambitious projects will ultimately be limited by the sensitivity
of the instrument and by the accuracy at which polarized foreground emission
from our own Galaxy can be subtracted out. We present the PILOT balloon project
which will aim at characterizing one of these foreground sources, the
polarization of the dust continuum emission in the diffuse interstellar medium.
The PILOT experiment will also constitute a test-bed for using multiplexed
bolometer arrays for polarization measurements. We present the results of
ground tests obtained just before the first flight of the instrument.Comment: 17 pages, 13 figures. Presented at SPIE, Millimeter, Submillimeter,
and Far-Infrared Detectors and Instrumentation for Astronomy VII. To be
published in Proc. SPIE volume 915
Recommended from our members
Impact of particles on the Planck HFI detectors: Ground-based measurements and physical interpretation
The Planck High Frequency Instrument (HFI) surveyed the sky continuously from
August 2009 to January 2012. Its noise and sensitivity performance were
excellent, but the rate of cosmic ray impacts on the HFI detectors was
unexpectedly high. Furthermore, collisions of cosmic rays with the focal plane
produced transient signals in the data (glitches) with a wide range of
characteristics. A study of cosmic ray impacts on the HFI detector modules has
been undertaken to categorize and characterize the glitches, to correct the HFI
time-ordered data, and understand the residual effects on Planck maps and data
products. This paper presents an evaluation of the physical origins of glitches
observed by the HFI detectors. In order to better understand the glitches
observed by HFI in flight, several ground-based experiments were conducted with
flight-spare HFI bolometer modules. The experiments were conducted between 2010
and 2013 with HFI test bolometers in different configurations using varying
particles and impact energies. The bolometer modules were exposed to 23 MeV
protons from the Orsay IPN TANDEM accelerator, and to Am and Cm
-particle and Fe radioactive X-ray sources. The calibration data
from the HFI ground-based preflight tests were used to further characterize the
glitches and compare glitch rates with statistical expectations under
laboratory conditions. Test results provide strong evidence that the dominant
family of glitches observed in flight are due to cosmic ray absorption by the
silicon die substrate on which the HFI detectors reside. Glitch energy is
propagated to the thermistor by ballistic phonons, while there is also a
thermal diffusion contribution. The implications of these results for future
satellite missions, especially those in the far-infrared to sub-millimetre and
millimetre regions of the electromagnetic spectrum, are discussed.Comment: 11 pages, 13 figure
Brachio-cephalic ('Gracz') fistula use for continuous hemofiltration in a hemodynamically unstable hemodialysis patient without venous vascular access: a case report
Even in patients with chronic renal failure and chronic intermittent hemodialysis, continuous venovenous hemofiltration (CVVH) is the most often practiced renal replacement technique in the intensive care unit. Although patients show less hemodynamic instability during CVVH than during hemodialysis, it requires a blood flow exceeding 200 ml/min in the extracorporeal circuit necessitating the use of large bore catheters. Vascular access in critically ill septic and edematous patients is sometimes difficult, or even impossible
International practice patterns and factors associated with non-conventional hemodialysis utilization
<p>Abstract</p> <p>Background</p> <p>The purpose of our study was to determine characteristics that influence the utilization of non-conventional hemodialysis (NCHD) therapies and its subtypes (nocturnal (NHD), short daily (SDHD), long conventional (LCHD) and conventional hemodialysis (CHD) as well as provider attitudes regarding the evidence for NCHD use.</p> <p>Methods</p> <p>An international cohort of subscribers of a nephrology education website <url>http://www.nephrologynow.com</url> was invited to participate in an online survey. Non-conventional hemodialysis was defined as any forms of hemodialysis delivered > 3 treatments per week and/or > 4 hours per session. NHD and SDHD included both home and in-centre. Respondents were categorized as CHD if their centre only offered conventional thrice weekly hemodialysis. Variables associated with NCHD and its subtypes were determined using multivariate logistic regression analysis. The survey assessed multiple domains regarding NCHD including reasons for initiating and discontinuing, for not offering and attitudes regarding evidence.</p> <p>Results</p> <p>544 surveys were completed leading to a 15.6% response rate. The final cohort was limited to 311 physicians. Dialysis modalities utilized among the respondents were as follows: NCHD194 (62.4%), NHD 83 (26.7%), SDHD 107 (34.4%), LCHD 81 (26%) and CHD 117 (37.6%). The geographic regions of participants were as follows: 11.9% Canada, 26.7% USA, 21.5% Europe, 6.1% Australia/New Zealand, 10% Africa/Middle East, 10.9% Asia and 12.9% South America. Variables associated with NCHD utilization included NCHD training (OR 2.47 CI 1.25-4.16), government physician reimbursement (OR 2.66, CI 1.11-6.40), practicing at an academic centre (OR 2.28 CI 1.25-4.16), higher national health care expenditure and number of ESRD patients per centre. Hemodialysis providers with patients on NCHD were significantly more likely to agree with the statements that NCHD improves quality of life, improves nutritional status, reduces EPO requirements and is cost effective. The most common reasons to initiate NCHD were driven by patient preference and the desire to improve volume control and global health outcomes.</p> <p>Conclusion</p> <p>Physician attitudes toward the evidence for NCHD differ significantly between NCHD providers and conventional HD providers. Interventions and health policy targeting these areas along with increased physician education and training in NCHD modalities may be effective in increasing its utilization.</p
The Planck High Frequency Instrument, a 3rd generation CMB experiment, and a full sky submillimeter survey
The High Frequency Instrument (HFI) of Planck is the most sensitive CMB
experiment ever planned. Statistical fluctuations (photon noise) of the CMB
itself will be the major limitation to the sensitivity of the CMB channels.
Higher frequency channels will measure galactic foregrounds. Together with the
Low Frequency Instrument, this will make a unique tool to measure the full sky
and to separate the various components of its spectrum. Measurement of the
polarization of these various components will give a new picture of the CMB. In
addition, HFI will provide the scientific community with new full sky maps of
intensity and polarization at six frequencies, with unprecedented angular
resolution and sensitivity. This paper describes the logics that prevailed to
define the HFI and the performances expected from this instrument. It details
several features of the HFI design that have not been published up to now.Comment: To be published in the proceedings of the workshop on "The Cosmic
Microwave Background and its Polarization", New Astronomy Reviews, (eds., S.
Hanany and R.A. Olive
Salt restriction in kidney disease—a missed therapeutic opportunity?
The importance of salt restriction in the treatment of patients with renal disease has remained highly controversial. In the following we marshal the current evidence that salt plays a definite role in the genesis of hypertension and target organ damage, point to practical problems of salt restriction, and report on novel pathomechanisms of how salt affects blood pressure and causes target organ damage
- …