210 research outputs found

    AN EXAMINATION OF THE CONCEPT "SOCIAL SOLIDARITY"

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    Although Durkheim's original definition of social solidarity included both beliefs and practices, modem sociologists have empirically operationalized the concept in terms of only beliefs or only practices. It is suggested that the modern conceptualization of social solidarity is invalid because it does not allow the researcher to get close to empirical reality

    A Framework for Reliability and Safety Analysis of Complex Space Missions

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    Long duration and complex mission scenarios are characteristics of NASA's human exploration of Mars, and will provide unprecedented challenges. Systems reliability and safety will become increasingly demanding and management of uncertainty will be increasingly important. NASA's current pioneering strategy recognizes and relies upon assurance of crew and asset safety. In this regard, flexibility to develop and innovate in the emergence of new design environments and methodologies, encompassing modeling of complex systems, is essential to meet the challenges

    Efferent Control of the Electrical and Mechanical Properties of Hair Cells in the Bullfrog's Sacculus

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    Background: Hair cells in the auditory, vestibular, and lateral-line systems respond to mechanical stimulation and transmit information to afferent nerve fibers. The sensitivity of mechanoelectrical transduction is modulated by the efferent pathway, whose activity usually reduces the responsiveness of hair cells. The basis of this effect remains unknown. Methodology and Principal Findings: We employed immunocytological, electrophysiological, and micromechanical approaches to characterize the anatomy of efferent innervation and the effect of efferent activity on the electrical and mechanical properties of hair cells in the bullfrog’s sacculus. We found that efferent fibers form extensive synaptic terminals on all macular and extramacular hair cells. Macular hair cells expressing the Ca 2+-buffering protein calretinin contain half as many synaptic ribbons and are innervated by twice as many efferent terminals as calretinin-negative hair cells. Efferent activity elicits inhibitory postsynaptic potentials in hair cells and thus inhibits their electrical resonance. In hair cells that exhibit spiking activity, efferent stimulation suppresses the generation of action potentials. Finally, efferent activity triggers a displacement of the hair bundle’s resting position. Conclusions and Significance: The hair cells of the bullfrog’s sacculus receive a rich efferent innervation with the heaviest projection to calretinin-containing cells. Stimulation of efferent axons desensitizes the hair cells and suppresses their spiking activity. Although efferent activation influences mechanoelectrical transduction, the mechanical effects on hair bundles ar

    Social Complexity and Nesting Habits Are Factors in the Evolution of Antimicrobial Defences in Wasps

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    Microbial diseases are important selective agents in social insects and one major defense mechanism is the secretion of cuticular antimicrobial compounds. We hypothesized that given differences in group size, social complexity, and nest type the secretions of these antimicrobials will be under different selective pressures. To test this we extracted secretions from nine wasp species of varying social complexity and nesting habits and assayed their antimicrobial compounds against cultures of Staphylococcus aureus. These data were then combined with phylogenetic data to provide an evolutionary context. Social species showed significantly higher (18x) antimicrobial activity than solitary species and species with paper nests showed significantly higher (11x) antimicrobial activity than those which excavated burrows. Mud-nest species showed no antimicrobial activity. Solitary, burrow-provisioning wasps diverged at more basal nodes of the phylogenetic trees, while social wasps diverged from the most recent nodes. These data suggest that antimicrobial defences may have evolved in response to ground-dwelling pathogens but the most important variable leading to increased antimicrobial strength was increase in group size and social complexity

    University of Oregon Department of Art MFA Thesis Exhibition Catalog

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    28 pagesEvery spring our graduating MFA candidates’ work emerges and activates the Art Department and the College of Design with an ethos of possibility and insight. Their creative research of new knowledge, or the rearrangement of old knowledge, brings with it the sense that a new day is rising. The 2021 MFA Thesis Exhibition culminates three years of independent research and experimentation by a cohort of eight artists whose various practices engage a broad range of inquiry, from expressions of the personal and diaristic to the examination and fictionalization of language, politics, and technology. While the world teetered this last year—fraught over the COVID-19 pandemic, racial injustice, and political chaos these candidates focused on their practices as the world blurred. They’ve shaped new strategies to teach on-line, built new curriculum to communicate remotely, and cloistered in their studios articulating their practices all the while navigating crisis shared with the nation. As the pandemic ebbs I hope the MFA Graduates of 2021 move forward with a sense of not only a new day rising but a new world emerging

    Crop Updates 2009 - Weeds

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    This session covers twenty three papers from different authors: Herbicides 1. New pre-seeding grass selective herbicides – How well do they work in zero or no-till systems? Dr Catherine Borgerand Dr Abul Hashem, Department of Agriculture and Food 2. Velocity®—An alternate mode of action for the control of wild radish in cereals, Mike Clarke, Bayer Cropscience Pty Ltd, Dr Aik Cheam, Department of Agriculture and Food, Dr Michael Walsh, WAHRI, University of Western Australia 3. Herbicide tolerance of new barley varieties, Harmohinder Dhammu, Vince Lambert, Chris Roberts and Russell Quartermaine, Department of Agriculture and Food 4. Herbicide tolerance of Desi chickpea – influence of seeding depth and rainfall, Harmohinder Dhammu, and David Nicholson, Department of Agriculture and Food 5. Herbicide tolerance of new wheat varieties, Harmohinder Dhammu, and David Nicholson, Department of Agriculture and Food 6. PARAGON plus Bromicide 200: a triple mode-of-action approach to combating wild radish, Raphanus raphanistrum, Mike Jackson and Bill Campbell, Nufarm Australia Limited 7. Interaction of glyphosate dose, annual ryegrass growth stage and environmental conditions on the performance of glyphosate for control of annual ryegrass, John Moore, Abul Hashem, Mario D’Antuono, Paul Matson and Dave Nicholson, Department of Agriculture and Food 8. Metribuzin pre-sowing of lupins, Peter Newman, Department of Agriculture and Food 9. Wild radish herbicides - you get what you pay for, Peter Newman, Department of Agriculture and Food 10. Glyphosate-the consequences of cutting rates, Sally Peltzer and Dave Minkey, Department of Agriculture and Food, and Australian Herbicide Resistance Initiative 11. Reasons to use only the full label herbicide rate, Stephen B Powles, Qin Yu, Mechelle Owen, Roberto Busi and Sudheesh Manalil, WA Herbicide Resistance Initiative, School of Plant Biology, University of Western Australia 12. Mandelup has reasonable tolerance to atrazine, Leigh Smith and Peter White, Department of Agriculture and Food Herbicide resistance 13. Risk of glyphosate resistance in wide-row lupin cropping systems, Fiona Evans, Abul Hashem and Art Diggle, Department of Agriculture and Food 14. More glyphosate-resistant annual ryegrass populations within Western Australia, Dr Abul Hashem and Dr Catherine Borger, Department of Agriculture and Food 15. Western Australian farmers are sowing herbicide-resistant weed seed into their cropping paddocks! Mechelle Owen1, Pippa Michael2and Stephen Powles1, 1WA Herbicide Resistance Initiative, School of Plant Biology, University of Western Australia, 2Muresk Institute, Curtin University of Technology Integrated Weed Management 16. Inversion ploughing: Effects of long-term deep burial on weed seed reserves, Aik Cheam and Siew Lee, Department of Agriculture and Food 17. How long cam wild radish seeds survive in the soil? Aik Cheam and Siew Lee, Department of Agriculture and Food 18. An economic comparison of IWM tools, Rob Grima, Department of Agriculture and Food 19. Emerging weeds in changing farming systems, Dr Abul Hashem, Department of Agriculture and Food 20. Eight years of IWM smashes ryegrass seed banks by 98 per cent over 31 focus paddocks, Peter Newman, Glenn Adam and Trevor Bell, Department of Agriculture and Food 21. Mouldboard plough - the answer to all the problems with sandplain farming! Peter Newman and Steve Davies, Department of Agriculture and Food 22. Flaxleaf fleabane - coming to a property near you! Sally Peltzer, Department of Agriculture and Food, 23. Trimming weed seed heads and crop-topping reduce seed bank of wild radish, Glen Riethmuller and Abul Hashem, Department of Agriculture and Foo

    Crop Updates 2009 - Genetically Modified Crops, Nutrition, Soils, & Others

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    This session covers fifteen papers from different authors: 1. Performance of Canola Breeders Roundup Ready® canola hybrid CHYB-166 in 2008, Wallace Cowling, Canola Breeders Western Australia Pty Ltd 2. The implications of GM glyphosate resistant lupin, Art Diggle, Caroline Peek, Frank D’Emden, Fiona Evans, Bob French, Rob Grima, Sam Harburg, Abul Hashem,, John Holmes, Jeremy Lemon, Peter Newman, Janet Paterson, Steve Penny,Department of Agriculture and Food, Peter Portmann, Agriconnect 3. Nufarm Roundup Ready® Canola Systems Trials— 2008 Mark Slatter, Research and Development Officer, Victoria, Nufarm (0438 064 845) Angus MacLennan, Business Development Manager, New South Wales, Nufarm (0408 358 024) Cooperators: Monsanto, Nuseed, Pacific Seeds, Pioneer Seeds 4. Roundup Ready® canola—2008 Limited Commercial Release. Getting the system right, Andrew Wells and Mark Slatter, Nufarm Australia Limited (Reprint from 2008 GRDC Cropping Updates with Introductory note) NUTRITION 5. Fertilising in a changing price environment, Bill Bowden1, Wayne Pluske2 and Jeremy Lemon1, 1Department of Agriculture and Food, 2Back Paddock Company 6. Making better fertiliser for Western Australian cropping systems, Wen Chen1 2, Geoff Anderson1, Ross Brennan1and Richard Bell2 1Department of Agriculture and Food, 2School of Environmental Science, Murdoch University 7. The nitrogen fertiliser replacement value of biosolids from wastewater treatment, Hannah Rigby1, Deborah Pritchard1, David Collins1, Katrina Walton2, David Allen2 and Nancy Penney31School of Agriculture and Environment,Curtin University of Technology, Muresk Campus, 2Chemistry Centre of Western Australia 3Water Corporation of Western Australia 8. Fertilising to soil type (usually) pays, Michael Robertson, Bill Bowden and Roger Lawes, CSIRO, Floreat and Department of Agriculture and Food SOILS 9. Management of subsoil acidity and compaction using a combination of lime, deep ripping and controlled traffic, Stephen Davies, Chris Gazey, Breanne Best and David Gartner, Department of Agriculture and Food 10. Optimising gypsum applications through remote sensing and Variable Rate Technology, Frank D’Emden, Department of Agriculture and Food and Quenten Knight,Precision Agronomics Australia 11. Case study of a 17 year agricultural lime trial, Chris Gazey1, Joel Andrew2and Ryan Pearce3 1Department of Agriculture and Food; 2Precision SoilTech; 3ConsultAg 12. Soil organic carbon in WA agricultural soils, FC Hoyle and A Bennett, Department of Agriculture and Food OTHER 13. Is the no-till revolution complete in WA? Frank D’Emden1, Rick Llewellyn2 and Ken Flower3 1Department of Agriculture and Food, 2CSIRO Sustainable Ecosystems, 3University of Western Australia 14. Progression Planning (The Concept), Julian Krieg and Owen Catto, Wheatbelt Men’s Health 15. Is the Department of Agriculture and Food still a primary source of cropping information? Cindy Parsons, Department of Agriculture and Foo

    Multiple Measures Reveal Antiretroviral Adherence Successes and Challenges in HIV-Infected Ugandan Children

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    Background: Adherence to HIV antiretroviral therapy (ART) among children in developing settings is poorly understood. Methodology/Principal Findings: To understand the level, distribution, and correlates of ART adherence behavior, we prospectively determined monthly ART adherence through multiple measures and six-monthly HIV RNA levels among 121 Ugandan children aged 2–10 years for one year. Median adherence levels were 100% by three-day recall, 97.4% by 30-day visual analog scale, 97.3% by unannounced pill count/liquid formulation weights, and 96.3% by medication event monitors (MEMS). Interruptions in MEMS adherence of ≥\geq48 hours were seen in 57.0% of children; 36.3% had detectable HIV RNA at one year. Only MEMS correlated significantly with HIV RNA levels (r = −0.25, p = 0.04). Multivariable regression found the following to be associated with <90% MEMS adherence: hospitalization of child (adjusted odds ratio [AOR] 3.0, 95% confidence interval [CI] 1.6–5.5; p = 0.001), liquid formulation use (AOR 1.4, 95%CI 1.0–2.0; p = 0.04), and caregiver’s alcohol use (AOR 3.1, 95%CI 1.8–5.2; p<0.0001). Child’s use of co-trimoxazole (AOR 0.5, 95%CI 0.4–0.9; p = 0.009), caregiver’s use of ART (AOR 0.6, 95%CI 0.4–0.9; p = 0.03), possible caregiver depression (AOR 0.6, 95%CI 0.4–0.8; p = 0.001), and caregiver feeling ashamed of child’s HIV status (AOR 0.5, 95%CI 0.3–0.6; p<0.0001) were protective against <90% MEMS adherence. Change in drug manufacturer (AOR 4.1, 95%CI 1.5–11.5; p = 0.009) and caregiver’s alcohol use (AOR 5.5, 95%CI 2.8–10.7; p<0.0001) were associated with ≥\geq48-hour interruptions by MEMS, while second-line ART (AOR 0.3, 95%CI 0.1–0.99; p = 0.049) and increasing assets (AOR 0.7, 95%CI 0.6–0.9; p = 0.0007) were protective against these interruptions. Conclusions/Significance: Adherence success depends on a well-established medication taking routine, including caregiver support and adequate education on medication changes. Caregiver-reported depression and shame may reflect fear of poor outcomes, functioning as motivation for the child to adhere. Further research is needed to better understand and build on these key influential factors for adherence intervention development
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