A Methodology to Consider Explicitly Emissions in Dynamic User Equilibrium Assignment

This work presents a methodology to obtain Dynamic User Equilibrium (DUE) over a road network considering the exhausted gas effect of motorized traffic. On purpose, three emission models are integrated to the traffic simulator AIMSUN, and an entire modeling structure is proposed. The proposed methodology is tested on both a hypothetical test network and a real-world network in Istanbul, Turkey. With the use of dynamic traffic assignment components of AIMSUN, emissions are incorporated into dynamic cost functions. Furthermore, link travel times are considered in the dynamic cost functions in conjunction with emissions. The DUE condition is converged according to dynamic cost functions. Results with the employment of different emission models on a real road network are compared and discussed

Efficacy and safety of an inactivated whole-virion SARS-CoV-2 vaccine (CoronaVac): interim results of a double-blind, randomised, placebo-controlled, phase 3 trial in Turkey.

Background CoronaVac, an inactivated whole-virion SARS-CoV-2 vaccine, has been shown to be well tolerated with a good safety profile in individuals aged 18 years and older in phase 1/2 trials, and provided a good humoral response against SARS-CoV-2. We present the interim efficacy and safety results of a phase 3 clinical trial of CoronaVac in Turkey