Peoples, Culture and Mass Media as Agent of Cultural Imperialism

Culture comprises the whole complex of distinctive spiritual, intellectual and emotional features that characterize society, our thought about life, and our ideas. Culture shape the way we see world, it has capacity to bring about the change of attitudes needed to ensure peace and sustainable development which we know form the only possible way forward for life on planet earth. This paper examined increasing in cultural dominance that one culture exerts over another as a function of the relation of both overall efficiencies, in the sense that flood of cultural elements pour from dominant culture on the dominated. Mass media was studied under the three theories: the limited effect theory, class Dominant theory and Culturalist theory. Mass media is found represents one of the most significant institutions, the powerful tool for socialization as well as cultural domination. Domination here means holding superiority or mastery in our strength and to suppress or overshadow us in dominance, recognition and prestige. It involves the exercise of great influence in the society as well as political and economic influence. The work suggests that, since communication is interwoven with every aspect of life, the future of mass media must be considered of utmost importance in overall social, cultural, moral, economic goals of the nation. To ensuring a bright future for our cultural heritage, we need a revolutionary Nigeria mass media which can present and carry forward revolutionary purpose of promoting our heritage

Global Retinoblastoma Presentation and Analysis by National Income Level

Importance: Early diagnosis of retinoblastoma, the most common intraocular cancer, can save both a child's life and vision. However, anecdotal evidence suggests that many children across the world are diagnosed late. To our knowledge, the clinical presentation of retinoblastoma has never been assessed on a global scale. Objectives: To report the retinoblastoma stage at diagnosis in patients across the world during a single year, to investigate associations between clinical variables and national income level, and to investigate risk factors for advanced disease at diagnosis. Design, Setting, and Participants: A total of 278 retinoblastoma treatment centers were recruited from June 2017 through December 2018 to participate in a cross-sectional analysis of treatment-naive patients with retinoblastoma who were diagnosed in 2017. Main Outcomes and Measures: Age at presentation, proportion of familial history of retinoblastoma, and tumor stage and metastasis. Results: The cohort included 4351 new patients from 153 countries; the median age at diagnosis was 30.5 (interquartile range, 18.3-45.9) months, and 1976 patients (45.4) were female. Most patients (n = 3685 84.7%) were from low-and middle-income countries (LMICs). Globally, the most common indication for referral was leukocoria (n = 2638 62.8%), followed by strabismus (n = 429 10.2%) and proptosis (n = 309 7.4%). Patients from high-income countries (HICs) were diagnosed at a median age of 14.1 months, with 656 of 666 (98.5%) patients having intraocular retinoblastoma and 2 (0.3%) having metastasis. Patients from low-income countries were diagnosed at a median age of 30.5 months, with 256 of 521 (49.1%) having extraocular retinoblastoma and 94 of 498 (18.9%) having metastasis. Lower national income level was associated with older presentation age, higher proportion of locally advanced disease and distant metastasis, and smaller proportion of familial history of retinoblastoma. Advanced disease at diagnosis was more common in LMICs even after adjusting for age (odds ratio for low-income countries vs upper-middle-income countries and HICs, 17.92 95% CI, 12.94-24.80, and for lower-middle-income countries vs upper-middle-income countries and HICs, 5.74 95% CI, 4.30-7.68). Conclusions and Relevance: This study is estimated to have included more than half of all new retinoblastoma cases worldwide in 2017. Children from LMICs, where the main global retinoblastoma burden lies, presented at an older age with more advanced disease and demonstrated a smaller proportion of familial history of retinoblastoma, likely because many do not reach a childbearing age. Given that retinoblastoma is curable, these data are concerning and mandate intervention at national and international levels. Further studies are needed to investigate factors, other than age at presentation, that may be associated with advanced disease in LMICs. © 2020 American Medical Association. All rights reserved

Phylogenetic analyses of bacteria associated with the processing of iru and ogiri condiments

Analysis of the bacterial community dynamics during the production of traditional fermented condiments is important for food safety assessment, quality control and development of starter culture technology. In this study, bacteria isolated during the processing of iru and ogiri, two commonly consumed condiments in Nigeria, were characterized based on phylogenetic analyses of the bacterial 16S rRNA gene. A total of 227 isolates were obtained and clustered into 12 operational taxonomic units (OTUs) based on 97% 16S rRNA gene similarity. The OTUs spanned three phyla (Firmicutes, Actinobacteria and Proteobacteria), and nine genera: Acinetobacter, Aerococcus, Bacillus, Enterococcus, Enterobacter, Lysinibacillus, Micrococcus, Proteus and Staphylococcus. OTUs closely related to species of Bacillus dominated the processing stages of both condiments. Although no single OTU occurred throughout iru processing stages, an OTU (mostly related to B. safensis) dominated the ogiri processing stages indicating potentials for the development of starter culture. However, other isolates such as those of Enterococcus spp. and Lysinibacillus spp. may be potential starters for iru fermentation. Presumptive food‐borne pathogens were also detected at some stages of the condiments’ processing, possibly due to poor hygienic practice

Global Retinoblastoma Presentation and Analysis by National Income Level

Importance: Early diagnosis of retinoblastoma, the most common intraocular cancer, can save both a child's life and vision. However, anecdotal evidence suggests that many children across the world are diagnosed late. To our knowledge, the clinical presentation of retinoblastoma has never been assessed on a global scale. Objectives: To report the retinoblastoma stage at diagnosis in patients across the world during a single year, to investigate associations between clinical variables and national income level, and to investigate risk factors for advanced disease at diagnosis. Design, Setting, and Participants: A total of 278 retinoblastoma treatment centers were recruited from June 2017 through December 2018 to participate in a cross-sectional analysis of treatment-naive patients with retinoblastoma who were diagnosed in 2017. Main Outcomes and Measures: Age at presentation, proportion of familial history of retinoblastoma, and tumor stage and metastasis. Results: The cohort included 4351 new patients from 153 countries; the median age at diagnosis was 30.5 (interquartile range, 18.3-45.9) months, and 1976 patients (45.4%) were female. Most patients (n = 3685 [84.7%]) were from low-and middle-income countries (LMICs). Globally, the most common indication for referral was leukocoria (n = 2638 [62.8%]), followed by strabismus (n = 429 [10.2%]) and proptosis (n = 309 [7.4%]). Patients from high-income countries (HICs) were diagnosed at a median age of 14.1 months, with 656 of 666 (98.5%) patients having intraocular retinoblastoma and 2 (0.3%) having metastasis. Patients from low-income countries were diagnosed at a median age of 30.5 months, with 256 of 521 (49.1%) having extraocular retinoblastoma and 94 of 498 (18.9%) having metastasis. Lower national income level was associated with older presentation age, higher proportion of locally advanced disease and distant metastasis, and smaller proportion of familial history of retinoblastoma. Advanced disease at diagnosis was more common in LMICs even after adjusting for age (odds ratio for low-income countries vs upper-middle-income countries and HICs, 17.92 [95% CI, 12.94-24.80], and for lower-middle-income countries vs upper-middle-income countries and HICs, 5.74 [95% CI, 4.30-7.68]). Conclusions and Relevance: This study is estimated to have included more than half of all new retinoblastoma cases worldwide in 2017. Children from LMICs, where the main global retinoblastoma burden lies, presented at an older age with more advanced disease and demonstrated a smaller proportion of familial history of retinoblastoma, likely because many do not reach a childbearing age. Given that retinoblastoma is curable, these data are concerning and mandate intervention at national and international levels. Further studies are needed to investigate factors, other than age at presentation, that may be associated with advanced disease in LMICs. © 2020 American Medical Association. All rights reserved.American Cancer Society, ACS; National Eye Institute, NEI; National Cancer Institute, NCI: K08CA232344; Knights Templar Eye Foundation, KTEF; Roche; Indiana University, IU; Ohio State University, OSU; Massachusetts Eye and Ear, MEE; University of Florida, UF; Michigan State University, MSU; Hyundai Hope On Wheels; University of Iowa, UI; University of Colorado, CU; Childhood Eye Cancer Trust, CHECT; Queen Elizabeth Diamond Jubilee TrustFoundation, and Research to Prevent Blindness. Dr Correa reports receiving personal fees from Castle Biosciences and Immunocore. Dr Diaz Coronado reports receiving support from Merck Sharp & Dohme. Dr Demirci reports receiving support Castle Biosciences and Immunocore. Dr Foster reports receiving grants from the Queen Elizabeth Diamond Jubilee Trust. Dr Gold reports receiving personal fees from Regeneron. Dr Harbour reports receiving royalties and other support from Castle Biosciences. Dr Hartnett reports receiving grants from the National Eye Institute; having a patent issued and a patent pending related to her work in eye care; receiving honoraria from Wolters Kluwer as editor in chief of the textbook Pediatric Retina Disease, Second Edition; receiving honoraria for academic lectures at the University of Alabama at Birmingham, Michigan State University, University of Florida, University of Iowa, Ohio State University, Indiana University, Cole Eye Institute, Scheie Eye Institute, Massachusetts Eye and Ear, and University of Colorado; and receiving paid trips to consult for the National Eye Institute’s National Advisory Eye Council and for grant review for the Knights Templar Eye Foundation. Dr Kivela reports receiving personal fees from Santen. Dr Materin reports receiving personal fees from IDEAYA Biosciences and Castle Biosciences. Dr Nair reports receiving personal fees from HelpMeSee and Carl Zeiss Meditec. Dr Oliver reports receiving grants from Roche. Dr Skalet reports receiving support as a consultant from Castle Biosciences and Immunocore. Dr Soebagjo reports rights to 2 licensed patents. Dr Stahl reports receiving personal fees from Avedro and nonfinancial support from Sydnexis.receiving grants from National Cancer Institute (K08CA232344), Wright Foundation, Knights Templar Eye Foundation, American Cancer Society, Hyundai Hope on Wheels, and Childhood Eye Cancer Trust, as well as nonfinancial support from Institute for Families, The Larry and Celia Mo

Urban Environmental Noise Pollution and Perceived Health Effects in Ibadan, Nigeria

Urban environmental noise pollution has impact on the quality of life and it is a serious health and social problem. The aim of this study was to assess the sources and noise levels, and possible impacts in selected residential neighbourhoods of Ibadan metropolis. Structured questionnaire was used to elicit information from respondents on demographic and neighbourhood characteristics, sources of noise and perceived effects of noise pollution. Noise level meter was used to determine the noise levels. Results showed that noise levels, sources and the period the noise level reaches its peak vary with population density and are shown on GIS maps. The mean noise values for the three residential neighbourhood groups were low density (LD), 53.10±2.80dB; medium density (MD), 68.45± 2.10dB and high density (HD), 68.36±1.92dB with the medium density neighbourhoods having the highest mean value. There is a significant difference in the noise levels in the three neighbourhood groups (F value=11.88 and p=0.000). However, the difference in noise levels between HD/LD and LD/MD areas was significant (p=0.000) while that between HD/MD areas was not significant (p=0.975). Of the three residential neighbourhoods, the highest mean noise level (85.80dB) was recorded at Bere junction while the lowest was at the foot of Bowers tower at Oke Are (48.65dB). Based on WHO 16-hour DNL criteria of 55dB for residential areas, only 16 (23.2%) locations in the three residential neighbourhood groups had noise values that were within the recommended limit. The study concludes that there is a need for formulation and enforcement of permissible noise levels/standards for residential neighbourhoods by the Federal Ministry of Environment instead of using the current eight-hour standard of 90dB which is for industrial settings

Global Retinoblastoma Presentation and Analysis by National Income Level

This cross-sectional analysis reports the retinoblastoma stage at diagnosis across the world during a single year, investigates associations between clinical variables and national income level, and investigates risk factors for advanced disease at diagnosis. Key PointsQuestionIs the income level of a country of residence associated with the clinical stage of presentation of patients with retinoblastoma? FindingsIn this cross-sectional analysis that included 4351 patients with newly diagnosed retinoblastoma, approximately half of all new retinoblastoma cases worldwide in 2017, 49.1\% of patients from low-income countries had extraocular tumor at time of diagnosis compared with 1.5\% of patients from high-income countries. MeaningThe clinical stage of presentation of retinoblastoma, which has a major influence on survival, significantly differs among patients from low-income and high-income countries, which may warrant intervention on national and international levels. ImportanceEarly diagnosis of retinoblastoma, the most common intraocular cancer, can save both a child's life and vision. However, anecdotal evidence suggests that many children across the world are diagnosed late. To our knowledge, the clinical presentation of retinoblastoma has never been assessed on a global scale. ObjectivesTo report the retinoblastoma stage at diagnosis in patients across the world during a single year, to investigate associations between clinical variables and national income level, and to investigate risk factors for advanced disease at diagnosis. Design, Setting, and ParticipantsA total of 278 retinoblastoma treatment centers were recruited from June 2017 through December 2018 to participate in a cross-sectional analysis of treatment-naive patients with retinoblastoma who were diagnosed in 2017. Main Outcomes and MeasuresAge at presentation, proportion of familial history of retinoblastoma, and tumor stage and metastasis. ResultsThe cohort included 4351 new patients from 153 countries; the median age at diagnosis was 30.5 (interquartile range, 18.3-45.9) months, and 1976 patients (45.4\%) were female. Most patients (n=3685 {[}84.7\%]) were from low- and middle-income countries (LMICs). Globally, the most common indication for referral was leukocoria (n=2638 {[}62.8\%]), followed by strabismus (n=429 {[}10.2\%]) and proptosis (n=309 {[}7.4\%]). Patients from high-income countries (HICs) were diagnosed at a median age of 14.1 months, with 656 of 666 (98.5\%) patients having intraocular retinoblastoma and 2 (0.3\%) having metastasis. Patients from low-income countries were diagnosed at a median age of 30.5 months, with 256 of 521 (49.1\%) having extraocular retinoblastoma and 94 of 498 (18.9\%) having metastasis. Lower national income level was associated with older presentation age, higher proportion of locally advanced disease and distant metastasis, and smaller proportion of familial history of retinoblastoma. Advanced disease at diagnosis was more common in LMICs even after adjusting for age (odds ratio for low-income countries vs upper-middle-income countries and HICs, 17.92 {[}95\% CI, 12.94-24.80], and for lower-middle-income countries vs upper-middle-income countries and HICs, 5.74 {[}95\% CI, 4.30-7.68]). Conclusions and RelevanceThis study is estimated to have included more than half of all new retinoblastoma cases worldwide in 2017. Children from LMICs, where the main global retinoblastoma burden lies, presented at an older age with more advanced disease and demonstrated a smaller proportion of familial history of retinoblastoma, likely because many do not reach a childbearing age. Given that retinoblastoma is curable, these data are concerning and mandate intervention at national and international levels. Further studies are needed to investigate factors, other than age at presentation, that may be associated with advanced disease in LMICs