Syndromic and Point-of-Care Molecular Testing

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Upper Limits from Counting Experiments with Multiple Pipelines

In counting experiments, one can set an upper limit on the rate of a Poisson process based on a count of the number of events observed due to the process. In some experiments, one makes several counts of the number of events, using different instruments, different event detection algorithms, or observations over multiple time intervals. We demonstrate how to generalize the classical frequentist upper limit calculation to the case where multiple counts of events are made over one or more time intervals using several (not necessarily independent) procedures. We show how different choices of the rank ordering of possible outcomes in the space of counts correspond to applying different levels of significance to the various measurements. We propose an ordering that is matched to the sensitivity of the different measurement procedures and show that in typical cases it gives stronger upper limits than other choices. As an example, we show how this method can be applied to searches for gravitational-wave bursts, where multiple burst-detection algorithms analyse the same data set, and demonstrate how a single combined upper limit can be set on the gravitational-wave burst rate.Comment: 26 pages (CQG style), 8 figures. Added study of robustness of limits

Computer modeling of a two-junction, monolithic cascade solar cell

The theory and design criteria for monolithic, two-junction cascade solar cells are described. The departure from the conventional solar cell analytical method and the reasons for using the integral form of the continuity equations are briefly discussed. The results of design optimization are presented. The energy conversion efficiency that is predicted for the optimized structure is greater than 30% at 300 K, AMO and one sun. The analytical method predicts device performance characteristics as a function of temperature. The range is restricted to 300 to 600 K. While the analysis is capable of determining most of the physical processes occurring in each of the individual layers, only the more significant device performance characteristics are presented

The Background Field Method as a Canonical Transformation

We construct explicitly the canonical transformation that controls the full dependence (local and non-local) of the vertex functional of a Yang-Mills theory on a background field. After showing that the canonical transformation found is nothing but a direct field-theoretic generalization of the Lie transform of classical analytical mechanics, we comment on a number of possible applications, and in particular the non perturbative implementation of the background field method on the lattice, the background field formulation of the two particle irreducible formalism, and, finally, the formulation of the Schwinger-Dyson series in the presence of topologically non-trivial configurations.Comment: 11 pages, REVTeX. References added, some explanations extended. Final version to appear in the journa

AlGaAs-GaAs cascade solar cell

Computer modeling studies are reported for a monolithic, two junction, cascade solar cell using the AlGaAs GaAs materials combination. An optimum design was obtained through a serial optimization procedure by which conversion efficiency is maximized for operation at 300 K, AM 0, and unity solar concentration. Under these conditions the upper limit on efficiency was shown to be in excess of 29 percent, provided surface recombination velocity did not exceed 10,000 cm/sec