Acute lower Limb Ischemia Caused by Fungal Infective Atrial Thrombus: A Case Report

Introduction: Septic thromboemboli have two consequences, ischemic and infection. In this paper we discuss a case with acute lower limb ischemia caused by fungal infective atrial thrombus. The patient underwent an anticoagulant therapy. Case presentation:                 A 43-year-old female patient who suffered from valvular heart disease (history of mitral and tricuspid valve replacement) was referred to the vascular surgery department of Modarres hospital with acute left limb ischemia. She underwent a successful emergency surgical thrombectomy. The pathological report of thrombus demonstrated fungal infection.  Conclusion: After surgical thrombectomy to control the acute lower limb ischemia, antimicrobial treatment of septic emboli is necessary

Cytotoxicity Comparison of a Calcium Silicate-Based Resin Cement versus Conventional Self-Adhesive Resin Cement and a Resin-Modified Glass Ionomer: Cell Viability Analysis

Objective: To compare the cytotoxicity level of a new calcium silicate-based resin cement (TheraCem) with two commonly used cements, including a conventional self-adhesive resin cement (Panavia SA) and a resin-modified glass ionomer cement (FujiCem2), on the human gingival fibroblast cells after 24 and 48 hours. Material and Methods: Twelve discs of each cement type were fabricated. The extract of cement disks was made by incubating them in the cell medium. Human gingival fibroblast cells were cultured and exposed to cement extracts for 24 h and 48 h. MTT assay was performed on extracts and optical density and cell viability rates were calculated by the spectrophotometer device at 570 nm. Data were analyzed using ANOVA and Tukey HSD tests. Results: The cell viability rates after 24 hours and 48 hours were as follows: TheraCem: 89.24% and 85.46%, Panavia SA: 49.51% and 46.57% and FujiCem2: 50.63% and 47.36%. TheraCem represented the highest cell viability rate. However, no significant difference was noted between Panavia SA and FujiCem2. Time had no significant effect on cell viability. Conclusion: TheraCem exhibited the best results among three tested cements and was considered non-toxic. Panavia SA and FujiCem2 were not significantly different regarding the cell viability rate. Time had no significant effect on the cytotoxicity level of cements

COVID-19-Related Spontaneous Pneumomediastinum: An Atypical Manifestation

COVID-19 is has been an emerging healthcare challenge during the last months. Herein we explain two cases with spontaneous pneumomediastinum as an atypical manifestation of COVID-19 disease; these two patients had confirmed COVID-19, leading to spontaneous pneumodeiastimun as an atypical manifestation during the course of hospital stay, presenting by abrupt deterioration in O2 saturation and symptoms. Spontaneous pneumomediastinum should be considered as a potential reason for the disease exacerbation in patients without previous history of mechanical ventilation. &nbsp

Designing and Validation of Consumers’ anxiety Management Pattern During the Economic Sanction on Iran

One of the most influential aspects of the economic embargo is the psychological dimension, which has negative effects on the economic structure of society. The aim of this study was to design and validate an anxiety management model in consumer behavior during the economic embargo on Iran. The approach of this research is deductive-inductive and from the perspective of the purpose of a fundamental research that has been mixed with the research method and based on empirical philosophy. The community of research participants in the model presentation section included theoretical experts (university professors) and experimental experts (executives and industry and business owners), 20 of whom were selected using purposive sampling in the ISM section. have became. The statistical population of the quantitative section including consumers of capital goods and samples in this section were estimated 384 people using Cochran's formula and were selected by Two-stage sampling method. Data collection tools were library studies and the use of a researcher-made questionnaire. In the qualitative part of the research, the meta-combined method has been used and the initial model has been designed with the ISM method and finally validated with the partial least squares method

Evaluation of Knowledge, Attitude, and Practice of Mothers Presenting to Pediatric Clinic Regarding Urinary Tract Infection Prevention in Children

Introduction: Urinary tract infection is one of the most common bacterial infections in children. It is preventable in many cases and appropriate health behaviors can protect a child from the disease or minimize its risk. Considering the relatively high prevalence of urinary tract infections in children and with regard to the important role of healthy behaviors in preventing this infection, we decided to evaluate the knowledge, attitude and practice of mothers regarding the prevention of urinary tract infections.Materials and Methods: This cross-sectional descriptive-analytic study was performed in the Pediatric Clinic of Imam Khomeini Hospital to determine the knowledge, attitude, and practice of mothers about UTI in children and to evaluate its relationships with some demographic features. The data collection tool was a researcher-made questionnaire based on the literature review. The collected data were analyzed using SPSS 22 software and P-values less than 5% were considered significant.Results: One hundred and fifteen mothers who presented to the Pediatric Clinic of Imam Khomeini Hospital participated in this study. The average knowledge, attitude, and practice score in the first part and the practice score in the second part was 6.21, 47.85, 13.86, and 10.66, respectively.A statistically significant relationship was found between the score of knowledge and attitude. The knowledge score had a significant relationship between maternal employment status, household income, and household location. There was also a significant relationship between access to information and both the knowledge and attitude scores.Conclusions: The significant relationship between access to information resources and the maternal knowledge and attitude scores confirms the importance of awareness in improving the knowledge of mothers in preventing urinary tract infection.Keywords: Knowledge; Attitudes; Practice; Urinary Tract Infections; Pediatrics

The role of long non-coding RNAs and circular RNAs in cervical cancer: modulating miRNA function

Cervical cancer (CC) is a primary global health concern, ranking as the fourth leading cause of cancer-related death in women. Despite advancements in prognosis, long-term outcomes remained poor. Beyond HPV, cofactors like dietary deficiencies, immunosuppression, hormonal contraceptives, co-infections, and genetic variations are involved in CC progression. The pathogenesis of various diseases, including cancer, has brought to light the critical regulatory roles of microRNAs (miRNAs), long non-coding RNAs (lncRNAs), and circular RNAs (circRNAs). The aberrant expression of these miRNAs, lncRNAs, and circRNAs plays a pivotal role in the initiation and progression of CC. This review provides a comprehensive summary of the recent literature regarding the involvement of lncRNAs and circRNAs in modulating miRNA functions in cervical neoplasia and metastasis. Studies have shown that lncRNAs and circRNAs hold great potential as therapeutic agents and innovative biomarkers in CC. However, more clinical research is needed to advance our understanding of the therapeutic benefits of circRNAs and lncRNAs in CC

The Study of Prevalence of Lipid Profile Abnormalities and its correlation with cardiovascular diseases regarding different environmental and genetic factors in Hemodialysis Patients of Vasee Hospital of Sabzevar in 2015

Introduction: Lipid disorders is a highly prevalent in patients on dialysis. Also the risk of cardiovascular disease increases with kidney failure. This study was conducted to evaluate the Prevalence of lipid profile abnormalities and its correlation with cardiovascular diseases regarding different environmental and genetic factors in hemodialysis patients of Vasee Hospital of Sabzevar in 2015. Method: This study was a cross–sectional that were evaluated all Patients that at least 12 weeks were on dialysis. Patient data includes demographic data and blood tests including serum levels of total cholesterol, triglycerides, HDL and LDL were extracted from medical records. Then the patient identifies and follow up and underwent echocardiography. Results: 54 patients were enrolled including 29 men (53.7%) and 25 women (46.3%). 31.5% of they, had abnormal serum triglycerides, 11.1% had abnormal serum cholesterol levels, 14.8% had abnormal serum levels of LDL and 72.2% had abnormal serum levels of HDL. The average of EF were 50.9±14.6% in patients. In terms of diastolic function, 29.6% had a normal function, 48.1% had grade 1 diastolic dysfunction, 14.8% had grade 2 diastolic dysfunction and 7.4% had grade 3 diastolic dysfunction. The association between duration of dialysis with Systolic and diastolic function was not significant. However, the amount of E, reduced with increasing duration of dialysis and PWDd and IVSd somewhat increased. There was no significant relationship between Systolic and diastolic function and dyslipidemia. However, in people who had dyslipidemia, the amount of EF was somewhat less and LViDs, LViDd and PWDd was over in this people. In addition, the E, A and Sm were also lower in these patients. Conclusion: Kidney failure is one of effective factors in the development dyslipidemia. It is recommended that review lipid profile and also blood pressure values in all cases with kidney failure and if needed to treatment, follow-up to be necessary. Also be checked in terms of cardiac dysfunction, all patients with dyslipidemia. Keywords: Dyslipidemia, Chronic renal failure, Dialysis, Cardiovascular disease, Echocardiograph

تاثير 8 هفته تمرينات تراباند بر درد، دامنه حرکتي و عملکرد پرستاران مبتلا به سندروم درد کشککي- راني

Background and Objectives: Patellofemoral pain syndrome is one of the most common disabilities among women. The purpose of the present study was to investigate the effect of eight weeks of Thera-band exercises on pain, range of motion, and function of nurses with patellofemoral pain syndrome. Methods and Materials: Thirty female nurses with patellofemoral pain syndrome were selected from the statistical population and divided into two groups of control and practice. After selecting subjects based on inclusion and exclusion criteria, in a pre-test, pain with visual analog scale, range of motion with a universal goniometer, and function with KOOS questioner were measured. Then the training group performed their Thera-band exercises for 8 weeks and in 3 sessions in a week. The control group was also prevented from doing any exercise program and they were only allowed to do their daily activities. Then all the tests that were taken in the pre-test phase, were measured in the post-test again. Paired t-test and independent t-test were used for statistical analysis of the results. In all statistical analyzes, alpha was smaller than 0.05. Results: The results of eight weeks of Thera-band exercises showed a reduction of the pain and induced an improvement of function in the subject of the exercise group. However, there was no significant difference between the post-test knee flexion range and pre-test in any of the study groups that indicates that the Thera-band exercises do not affect the range of motion of the knee flexion. Conclusion: According to the results of this study, it is recommended that women with patellofemoral pain syndrome use Thera-band exercises to reduce their pain. Besides, the Thera-band exercises can be introduced to these individuals as an appropriate solution to improve their performance. How to cite this article: Mazhari-Abbasi F, Tabatabaei H. The Effect of 8 Weeks the Thera-Band Exercises on Pain, Range of Motion and Function in Nurses with Patellofemoral Pain Syndrome. J Saf Promot Inj Prev. 2021; 9(1):27-34.سابقه و هدف: سندروم درد کشککی- رانی یکی از شایعترین اختلالات در میان زنان است. هدف از تحقیق حاضر، بررسی اثر هشت هفته تمرینات تراباند بر درد، دامنه حرکتی و عملکرد زنان پرستار مبتلا به سندروم درد کشککی- رانی بود. روش بررسی: تعداد 30 پرستار زن مبتلا به سندروم درد کشککی- رانی از بین جامعه آماری انتخاب و در دو گروه کنترل و مداخله قرار گرفتند. پس از انتخاب آزمودنیهای براساس معیارهای ورود و خروج از تحقیق، در جلسه پیشآزمون، درد به وسیله شاخص بصری، دامنه حرکتی خم شدن زانو بوسیله گونیامتر یونیورسال و عملکرد آزمودنیها بوسیله پرسشنامه کاوس اندازهگیری شد. سپس گروه مداخله به مدت هشت هفته و سه جلسه در هفته تمرینات تراباند را انجام دادند. گروه کنترل نیز از انجام هرگونه برنامه تمرینی منع شدند و تنها مجاز به انجام فعالیتهای روزمره خود بودند. پس از اتمام هشت هفته تمرینات، تمامی آزمونهایی که در مرحله پیشآزمون گرفته شده بود، مجددا و در مرحله پسآزمون اندازهگیری شد. از روشهای آماری تی زوجی و تی مستقل جهت تجزیه و تحلیل آماری نتایج تحقیق استفاده شد. در تمامی تجزیه و تحلیلهای آماری آلفا کوچکتر یا مساوی 05/0 در نظر گرفته شد.   یافته ها: نتایج تحقیق نشان داد که انجام هشت هفته تمرینات تراباند در گروه مداخله موجب کاهش شاخص درد و بهبود عملکرد آزمودنیها در پسآزمون نسبت به پیشآزمون شد. درحالیکه تفاوت معنیداری بین دامنه حرکتی خم شدن زانو در پسآزمون نسبت به پیشآزمون در هیچیک از گروههای تحقیق مشاهده نشد که نشان از عدم تاثیرگذاری تمرینات تراباند بر دامنه حرکتی خم شدن زانو داشت. نتیجه گیری: با توجه به نتایج تحقیق حاضر پیشنهاد میشود که زنان مبتلا به سندروم درد کشککی- رانی از تمرینات تراباند جهت کاهش درد خود استفاده نمایند. همچنین تمرینات تراباند میتواند به عنوان راهکاری مناسب جهت بهبود عملکرد این افراد معرفی شود. How to cite this article: Mazhari-Abbasi F, Tabatabaei H. The Effect of 8 Weeks the Thera-Band Exercises on Pain, Range of Motion and Function in Nurses with Patellofemoral Pain Syndrome. J Saf Promot Inj Prev. 2021; 9(1):27-34

Investigating the Anti-Depressant and Anxiolytic Effects of the Rosa canina L. Fruit in Syrian Rats Treated with Bisphenol A

Background & objectives: The pathophysiology of depression is very complex. Rosa canina L fruit contains various antioxidant compounds. The aim of this study was to investigate the anti-depressant and anti-anxiety effects of the aqueous- alcoholic extract of the Rosa canina L fruit in the behavioral tests including forced swimming, tail suspension, maze, and sucrose preference tests, as well as biochemical tests such as antioxidant capacity and malondialdehyde levels. Rosa canina L with high amounts of vitamin C, has anti-depressant and anxiety effects. Methods: In this experimental study, 60 Syrian male mice were divided into 5 groups of 12, including the control group, the bisphenol A group, and three groups treated with oral bisphenol A at a dose of 125 mg/kg per day and the aqueous- alcoholic extract of the Rosa canina L fruit at doses of 100, 200, 400 mg/kg/day was administered from day 50 to 120 after birth. The data were analyzed using SPSS statistical software and the One Way ANOVA test. The level of significance was set at p<0.05. Results: The findings showed that bisphenol A significantly increased the duration of immobility in the forced swimming and tail suspension test. The extract at the level of 400 mg/kg decreased the duration of immobility in both tests. Bisphenol A significantly reduced the antioxidant capacity of serum and brain. The extract at the level of 400 mg/kg significantly increased the antioxidant capacity of both the brain and serum. Conclusion: The findings of this research showed that the fruit of the Rosa canina L has antioxidant effects, and with a significant decrease in antioxidant capacity and immobility in Syrian mice treated with the extract, therefore it has anti-depressant and anxiety effects