3,694 research outputs found

    Town of Strafford NROC Projects

    Get PDF
    The three Strafford committees formed through the work with the Natural Resources Outreach Coalition in 2004 and supported by the grant award from the New Hampshire Estuaries Project have succeeded in furthering land protection, water quality protection, and managing growth here in Strafford. The original NROC meetings brought many new volunteer citizens into the process, but even their enthusiasm and willingness to work could not have earned these results without the financial support of the NHEP grant award. Hours of letter writing and personal contact with landowners by the volunteers of the Land Protection Group have raised awareness of the need for land protection and the ways it can be accomplished. The previous experience of the Strafford Conservation Commission in working with a landowner who was donating an easement showed us that the legal and logistical work involved is daunting. The NHEP grant allowed the land Protection Group to contract the professional services of Dan Kern of Bear-Paw Regional Greenways. His work streamlined the process for the landowners, and the Land Protection Group was able to celebrate the closing of two donated easements in 2006. Several other landowners have begun the process to protect their lands, and the Land Protection Group will continue its volunteer work. The Water Quality Group was pleased to have more than a dozen volunteers willing to focus on the need for tributary monitoring as a way to gauge and protect Bow Lake’s water quality. Testing supplies from the grant funds were essential. The sample gathering carried out at two-week intervals took place at a critical time for Bow Lake studies. Both Strafford and Northwood were in a period of legal moratorium on new development, and tributary monitoring at this time provides unique baseline data. It was not only useful in the establishment of Strafford’s Wetlands Overlay District ordinance, but will be used in future Bow Lake studies. After the Managed Growth Committee spent its time discovering gaps between the goals of the 2002 Strafford Master Plan and the present Strafford ordinances, Strafford Regional Planning Commission members helped with research for ordinances that had worked in other towns. The grant funds allowed the Committee to keep the public involved in the process and aware of the slate of proposed new ordinances that were coming up on the 2006 ballot. The blanket mailing to every Strafford address and the public meeting that followed are largely responsible for the successful passage of three new growth control ordinances. The Committee continued its work and has new measures to present to the town in 2007. The impetus and organization from NROC, and the financial support from NHEP have been a great gift to the Town of Strafford. Our thanks will be evident in the continued work and progress we make in protecting our land and water and the very nature of our town

    Episode-like pulse testosterone supplementation induces tumor senescence and growth arrest down-modulating androgen receptor through modulation of p-ERK1/2, pAR ser81 and CDK1 signaling: biological implications for men treated with testosterone replacement therapy

    Get PDF
    Despite the growing body of knowledge showing that testosterone (T) may not significantly affect tumor progression in hypogonadal patients treated for prostate cancer (Pca), the use of this hormone in this population still remains controversial. The effects of continuous or pulsed T stimulation were tested in vitro and in vivo on androgen-sensitive Pca cell lines in order to assess the differential biological properties of these two treatment modalities. Pulsed T treatment resulted in a greater inhibition than continuous T supplementation of tumor growth in vitro and in vivo. The effects of pulsed T treatment on tumor growth inhibition, G0/G1 cell cycle arrest, and tumor senescence was more pronounced than those obtained upon continuous T treatments. Mechanistic studies revealed that G0/G1 arrest and tumor senescence upon pulsed T treatment were associated with a marked decrease in cyclin D1, c-Myc and SKp2, CDK4 and p-Rb levels and upregulation of p27 and p-ERK1/2. Pulsed, but not continuous, T supplementation decreased the expression levels of AR, p-AR ser81 and CDK1 in both cellular models. The in vitro results were confirmed in an in vivo xenografts, providing evidence of a greater inhibitory activity of pulsed supraphysiological T supplementation than continuous treatment, both in terms of tumor volume and decreased AR, p-AR ser81 , PSA and CDK1 staining. The rapid cycling from hypogonadal to physiological or supra-physiological T intraprostatic concentrations results in cytostatic and senescence effects in preclinical models of androgen-sensitive Pca. Our preclinical evidence provides relevant new insights in the biology of Pca response to pulsed T supplementation

    Holographic Multiverse

    Full text link
    We explore the idea that the dynamics of the inflationary multiverse is encoded in its future boundary, where it is described by a lower dimensional theory which is conformally invariant in the UV. We propose that a measure for the multiverse, which is needed in order to extract quantitative probabilistic predictions, can be derived in terms of the boundary theory by imposing a UV cutoff. In the inflationary bulk, this is closely related (though not identical) to the so-called scale factor cutoff measure.Comment: 23 pages, 4 figures. Replaced to match published versio

    Título: Dos valses

    Get PDF
    Orgánico: 2 2 2 2 -- 4 2 3 0 -- tmp + 2 -- strperc: sd, chimes, tri, bdDuración: 2:30Copia digital. España : Ministerio de Cultura y Deporte. Subdirección General de Coordinación Bibliotecaria, s2021Tít. de la carp.: `1. Two Waltzes ...`Partes: Fl 1, 2, Ob 1, 2, Cl 1, 2, Bn 1, 2, Hn 1, 2, 3, 4, Tp 1, 2, Tbn 1, 2, 3, Tmp, Sd + Chimes + Tri + Bd, Vn 1 (5), Vn 2 (5), Va (3), Vc (3), Db (3

    Reference to the index of Oscar Jones, Solicitor of Murdoch and Jones, Queenstown branch, 1896-1902.

    Get PDF
    Papers of Oscar Jones, solicitor of Murdoch & Jones Queenstown branch and his predecessor AL Williams, apparently found at Strathelie, formerly the Jones family home. The papers are business papers of the Queenstown branch of solicitors Murdoch & Jones, formerly Williams & Page, including mine share business. There are also a few personal papers of AL Williams and of Oscar Jones.The Queenstown practice was established by AL Williams in 1896. Later Charles Page became a partner and established an office at Zeehan. George Murdoch of the Stone Buildings, Hobart, later Murdoch and Jones, acted as Hobart agent and early in 1898 the two firms merged as Williams and Page of Hobart, Queenstown and Zeehan. In April 1899, however, Williams sold out to Murdoch and Jones, Oscar Jones managed the Queenstown branch and by July the firm's name was changed to Murdoch & Jones. Williams & Page remained in Zeehan, under C.S. Page

    Hubungan Supervisi Kepala Ruangan Dengan Pendokumentasian Asuhan Keperawatan di Ruang Rawat Inap RSUD Majene

    Get PDF
    Supervisi adalah suatu kegiatan profesional dalam pelayanan keperawatan yang dilakukan oleh kepala ruangan dan bertujuan untuk meningkatkan produktivitas kerja perawat pelaksana, termasuk dalam dokumen keperawatan agar segala kegiatan yang telah diprogram dapat dilaksanakan dengan baik dan lancer. Dokumentasi asuhan keperawatan adalah aspek penting dalam proses keperawatan dan juga merupakan suatu indikator dalam meningkatkan mutu pelayanan keperawatan di rumah sakit. Penelitian ini bertujuan untuk mengetahui hubungan supervisi kepala ruangan dengan pendokumentasian asuhan keperawatan di ruangan inap RSUD Majene. Metode penelitian yang digunakan dalam penelitian ini adalah deskriktif korelasional dengan menggunakan desain cross-sectional. Hasil Penelitian menunjukkan Responden supervisi 103 (88,0%) di antaranya terkategorikan baik dan 14 responden (12,0%) di kategorikan cukup baik, kelengkapan pendokumentasian asuhan keperawatan ketegori lengkap 86 (73,5%) responden dan 31 (26,5%) responden tidak lengkap. Hubungan supervise kepala ruang terhadap pendokumentasian asuhan keperawatan dari hasil uji Chi-Square dengan nilai P=0,000. Kesimpulannya adalah ada hubungan supervisi kepala ruangan dengan pendokumentasian asuhan keperawatan di Ruang rawat inap RSUD Majen

    Suppression of core polarization in halo nuclei

    Get PDF
    We present a microscopic study of halo nuclei, starting from the Paris and Bonn potentials and employing a two-frequency shell model approach. It is found that the core-polarization effect is dramatically suppressed in such nuclei. Consequently the effective interaction for halo nucleons is almost entirely given by the bare G-matrix alone, which presently can be evaluated with a high degree of accuracy. The experimental pairing energies between the two halo neutrons in 6^6He and 11^{11}Li nuclei are satisfactorily reproduced by our calculation. It is suggested that the fundamental nucleon-nucleon interaction can be probed in a clearer and more direct way in halo nuclei than in ordinary nuclei.Comment: 11 pages, RevTex, 2 postscript figures; major revisions, matches version to appear in Phys. Rev. Letter
    • …
    corecore