Khaul and Maqam Thariqath in Sufism: the Analysis of Implementation Inside the Live of Sufi Thariqath Naqshabandiyah at Dawe Kudus Boarding School

The core of all religions are surrender to The God, as the Creator of all universe. The term of surrender generically called Islam in the Arabic terminology. Personal surrender to God The Ultimate Being, as the most right a part of self religious attitude. This attitude do not consider which any form of the people religious formation. Furthermore, apart form from this religious personality really rejected. According to the conceptualization of religious personality above, the sufism prosecuted to spell out all it\u27s doctrines related to cultural and social analysis. The sufism assumpt about religious multiculturality as the only form of religion in the world, while the nature it\u27s similar, that worship in source of anything. The Sufi as they stay in some stage on viewing about God, he will look at Him as essence not as the outer side of His perception. This reasearch stand by qualitative approach. The result of research aim about correlation between religion and society are creates the influence of the two sides. The religion influence the society otherwise the society influence the religion. This reciprocal influences, between the development of society and the improvement of religion, as social and cultural realities that\u27s need to be wider understand and deep perception

Synthesis and Evaluation of Protein-Phenylboronic Acid Conjugates as Lectin Mimetics

Glycan-binding molecules, such as lectins, are very important tools for characterizing, imaging, or targeting glycans and are often involved in either physiological or pathological processes. However, their availability is far less compared to the diversity of native glycans. Therefore, development of lectin mimetics with desired specificity and affinity is in high demand. Boronic acid reacts with 1,2- and 1,3-diols of saccharides in aqueous media through reversible boronate ester formation and are regarded as synthetic lectin mimetics. In this study, bovine serum albumin (BSA)-phenylboronic acid (PBA) conjugates were synthesized in a density-controlled manner by targeting both aspartic and glutamic acids to afford lectin mimetics with multivalent PBA, as multivalency is a key factor for glycan recognition in both specificity and affinity. The resultant BSA-PBA conjugates were characterized by sodium dodecyl sulfate polyacrylamide gel electrophoresis and matrix-assisted laser desorption/ionization time-of-flight mass spectrometry analysis. Their macrophage cell surface glycan-binding capacity was characterized by a competitive lectin-binding assay examined by flow cytometry, and 3-(4,5-di-methylthiazol-2-yl)-2,5 -diphenyltetrazolium bromide assay showed biocompatibility. These novel lectin mimetics will find a broad range of applications as they can be wittingly modified, altering binding specificity and capacity

Bisphosphonate-loaded PLGA microspheres for bone regeneration in dental surgery: formulation, characterization, stability, and comprehensive release kinetic studies

Bone regeneration is critical process Bone regeneration is critical process in maxillofacial surgery for preventing complications of osteo-clastic activity. Alendronate sodium is widely used bisphosphonate for bone regeneration. Itspoor-bioavailability and side effects are still challenging. In this study, poly(lactic-co-glycolic acid)(PLGA) microspheres showed sustained release of alendronate sodium to provide potential pro-longed residence at the operation site. Characterization, morphology, stability, and release kineticswere analyzed. Release kinetics found to fit multiple models, release mechanism was shown to becombined in relation to Fickian diffusion and polymer erosion. Consequently, alendronate-loadedPLGA microspheres were elucidated in detail and presented as a locally applicable drug deliverysystem in maxillofacial surgeryin maxillofacial surgery for preventing complications of osteo-clastic activity. Alendronate sodium is widely used bisphosphonate for bone regeneration. Itspoor-bioavailability and side effects are still challenging. In this study, poly(lactic-co-glycolic acid)(PLGA) microspheres showed sustained release of alendronate sodium to provide potential pro-longed residence at the operation site. Characterization, morphology, stability, and release kineticswere analyzed. Release kinetics found to fit multiple models, release mechanism was shown to becombined in relation to Fickian diffusion and polymer erosion. Consequently, alendronate-loadedPLGA microspheres were elucidated in detail and presented as a locally applicable drug deliverysystem in maxillofacial surgery</p

Sağlık Bilimlerine Psikolojinin Büyük Katkı Yapacağı Bir Alan: Sağlık Psikolojisi

Sağlık Psikolojisi, ilk kez 1978 yılında Matarazzo tarafından tanımlanmış olup sağlığın geliştirilmesi ve sürdürülmesini, hastalıkların ve ilgili işlev kayıplarının azaltılmasını ve psikoterapisini amaçlayan psikolojinin oldukça genç bir alanıdır. Kronik hastalıklara yaşam süresince artık daha sık rastlanması, zaman içinde hastalıklar üzerindeki biyolojik ve fizyolojik etkenlerin yanı sıra psikolojik faktörlerin de etkili olduğunun görülmesi, artan araştırmalar ve sağlık hizmetleri içinde psikologların daha fazla yer almaya başlaması sağlık psikolojisinin doğmasını sağlayan önemli etkenler olmuştur. Sağlık psikologları önleyici çalışmaların (kadın sağlığı, yeme bozuklukları, sigarayı bırakma birimleri) yanı sıra hastanelerde farklı birimlerde (onkoloji, ağrı yönetimi, diyaliz), rehabilitasyon ve ağrı merkezlerinde çalışabilmektedirler. Davranışsal değerlendirmeler, klinik görüşmeler ve psikoterapötik müdahaleler yapabilmektedirler. Bununla birlikte sağlığın geliştirilmesi ve sürdürülmesi amacıyla kamu politikası çalışmalarına da katkıda bulunabilmektedirler. Üniversitelerin Psikoloji bölümlerinde, Tıp ve Sağlık Bilimleri Fakültelerinde araştırmacı, eğitimci olarak yer alabilmektedirler. Sağlık psikolojisi eğitiminde özellikle Amerika Birleşik Devletlerinde belli bir standardizasyon oluşturulmaya çalışılmaktadır. Türkiye’de çok yaygın olmamakla birlikte sağlık psikolojisi alanına yönelik yüksek lisans ve doktora eğitimleri denenmektedir. Giderek artan araştırmalar ve sağlık psikologlarının farklı düzeylerde sağlığa katkısı sayesinde alana duyulan ilgi de artmaktadır