Infrared spectroscopy of HCOOH in interstellar ice analogues

Context: HCOOH is one of the more common species in interstellar ices with abundances of 1-5% with respect to solid H2O. Aims: This study aims at characterizing the HCOOH spectral features in astrophysically relevant ice mixtures in order to interpret astronomical data. Methods: The ices are grown under high vacuum conditions and spectra are recorded in transmission using a Fourier transform infrared spectrometer. Pure HCOOH ices deposited at 15 K and 145 K are studied, as well as binary and tertiary mixtures containing H2O, CO, CO2 and CH3OH. The mixture concentrations are varied from 50:50% to ~10:90% for HCOOH:H2O. Binary mixtures of HCOOH:X and tertiary mixtures of HCOOH:H2O:X with X = CO, CO2, and CH3OH, are studied for concentrations of ~10:90% and ~7:67:26%, respectively. Results: Pure HCOOH ice spectra show broad bands which split around 120 K due to the conversion of a dimer to a chain-structure. Broad single component bands are found for mixtures with H2O. Additional spectral components are present in mixtures with CO, CO2 and CH3OH. The resulting peak position, full width at half maximum and band strength depend strongly on ice structure, temperature, matrix constituents and the HCOOH concentration. Comparison of the solid HCOOH 5.9, 7.2, and 8.1 micron features with astronomical data toward the low mass source HH 46 and high mass source W 33A shows that spectra of binary mixtures do not reproduce the observed ice features. However, our tertiary mixtures especially with CH3OH match the astronomical data very well. Thus interstellar HCOOH is most likely present in tertiary or more complex mixtures with H2O, CH3OH and potentially also CO or CO2, providing constraints on its formation.Comment: 11 pages, 10 figures, accepted by A&

Is it time to reappraise blood pressure thresholds and targets? Statement from the international society of hypertension - a global perspective

No abstract available

A New Galactic 6cm Formaldehyde Maser

We report the detection of a new H2CO maser in the massive star forming region G23.71-0.20 (IRAS 18324-0820), i.e., the fifth region in the Galaxy where H2CO maser emission has been found. The new H2CO maser is located toward a compact HII region, and is coincident in velocity and position with 6.7 GHz methanol masers and with an IR source as revealed by Spitzer/IRAC GLIMPSE data. The coincidence with an IR source and 6.7 GHz methanol masers suggests that the maser is in close proximity to an embedded massive protostar. Thus, the detection of H2CO maser emission toward G23.71-0.20 supports the trend that H2CO 6cm masers trace molecular material very near young massive stellar objects.Comment: Accepted for publication in The Astrophysical Journal Letter

Ices in the edge-on disk CRBR 2422.8-3423: Spitzer spectroscopy and Monte Carlo radiative transfer modeling

We present 5.2-37.2 micron spectroscopy of the edge-on circumstellar disk CRBR 2422.8-3423 obtained using the InfraRed Spectrograph (IRS) of the Spitzer Space Telescope. The IRS spectrum is combined with ground-based 3-5 micron spectroscopy to obtain a complete inventory of solid state material present along the line of sight toward the source. We model the object with a 2D axisymmetric (effectively 3D) Monte Carlo radiative transfer code. It is found that the model disk, assuming a standard flaring structure, is too warm to contain the very large observed column density of pure CO ice, but is possibly responsible for up to 50% of the water, CO2 and minor ice species. In particular the 6.85 micron band, tentatively due to NH4+, exhibits a prominent red wing, indicating a significant contribution from warm ice in the disk. It is argued that the pure CO ice is located in the dense core Oph-F in front of the source seen in the submillimeter imaging, with the CO gas in the core highly depleted. The model is used to predict which circumstances are most favourable for direct observations of ices in edge-on circumstellar disks. Ice bands will in general be deepest for inclinations similar to the disk opening angle, i.e. ~70 degrees. Due to the high optical depths of typical disk mid-planes, ice absorption bands will often probe warmer ice located in the upper layers of nearly edge-on disks. The ratios between different ice bands are found to vary by up to an order of magnitude depending on disk inclination due to radiative transfer effects caused by the 2D structure of the disk. Ratios between ice bands of the same species can therefore be used to constrain the location of the ices in a circumstellar disk. [Abstract abridged]Comment: 49 pages, accepted for publication in Ap

Inflammation and salt in young adults: the African-PREDICT study

Purpose: Low-grade inflammation and a diet high in salt are both established risk factors for cardiovascular disease. High potassium (K+) intake was found to counter increase in blood pressure due to high salt intake and may potentially also have protective anti-inflammatory effects. To better understand these interactions under normal physiological conditions, we investigated the relationships between 22 inflammatory mediators with 24-h urinary K+ in young healthy adults stratified by low, medium and high salt intake (salt tertiles). We stratified by ethnicity due to potential salt sensitivity in black populations. Methods: In 991 healthy black (N = 457) and white (N = 534) adults, aged 20–30 years, with complete data for 24-h urinary sodium and K+, we analysed blood samples for 22 inflammatory mediators. Results: We found no differences in inflammatory mediators between low-, mid- and high-sodium tertiles in either the black or white groups. In multivariable-adjusted regression analyses in white adults, we found only in the lowest salt tertile that K+ associated negatively with pro-inflammatory mediators, namely interferon gamma, interleukin (IL) -7, IL-12, IL-17A, IL-23 and tumour necrosis factor alpha (all p ≤ 0.046). In the black population, we found no independent associations between K+ and any inflammatory mediator. Conclusion: In healthy white adults, 24-h urinary K+ associated independently and negatively with specific pro-inflammatory mediators, but only in those with a daily salt intake less than 6.31 g, suggesting K+ to play a protective, anti-inflammatory role in a low-sodium environment. No similar associations were found in young healthy black adults

Orbiting Resonances and Bound States in Molecular Scattering

A family of orbiting resonances in molecular scattering is globally described by using a single pole moving in the complex angular momentum plane. The extrapolation of this pole at negative energies gives the location of the bound states. Then a single pole trajectory, that connects a rotational band of bound states and orbiting resonances, is obtained. These complex angular momentum singularities are derived through a geometrical theory of the orbiting. The downward crossing of the phase-shifts through pi/2, due to the repulsive region of the molecular potential, is estimated by using a simple hard-core model. Some remarks about the difference between diffracted rays and orbiting are also given.Comment: 18 pages, 3 figures, to appear in Physical Review

VLT-ISAAC 3-5 micron spectroscopy of embedded young low-mass stars. III. Intermediate-mass sources in Vela

We performed a spectroscopic survey toward five intermediate-mass class I YSOs located in the Southern Vela molecular cloud in the L and M bands at resolving powers 600-800 up to 10,000, using the Infrared Spectrometer and Array Camera mounted on the VLT-ANTU. Lower mass companion objects were observed simultaneously in both bands. Solid H2O at 3 micron is detected in all sources, including the companion objects. CO ice at 4.67 micron is detected in a few main targets and one companion object. One object (LLN 19) shows little CO ice but strong gas-phase CO ro-vibrational lines in absorption. The CO ice profiles are different from source to source. The amount of water ice and CO ice trapped in a water-rich mantle may correlate with the flux ratio at 12 and 25 micron. The abundance of H2O-rich CO likely correlates with that of water ice. A weak feature at 3.54 mu attributed to solid CH3OH and a broad feature near 4.62 mu are observed toward LLN17, but not toward the other sources. The derived abundances of solid CH3OH and OCN- are ~10% and ~1% of the H2O ice abundance respectively. The H2O optical depths do not show an increase with envelope mass, nor do they show lower values for the companion objects compared with the main protostar. The line-of-sight CO ice abundance does not correlate with the source bolometric luminosity. Comparison of the solid CO profile toward LLN17, which shows an extremely broad CO ice feature, and that of its lower mass companion at a few thousand AU, which exhibits a narrow profile, together with the detection of OCN- toward LLN17 provide direct evidences for local thermal processing of the ice.Comment: Replace wrong files. Accepted by A&A, 22 pages, 18 figure

Blackbody-radiation-assisted molecular laser cooling

The translational motion of molecular ions can be effectively cooled sympathetically to temperatures below 100 mK in ion traps through Coulomb interactions with laser-cooled atomic ions. The distribution of internal rovibrational states, however, gets in thermal equilibrium with the typically much higher temperature of the environment within tens of seconds. We consider a concept for rotational cooling of such internally hot, but translationally cold heteronuclear diatomic molecular ions. The scheme relies on a combination of optical pumping from a few specific rotational levels into a ``dark state'' with redistribution of rotational populations mediated by blackbody radiation.Comment: 4 pages, 5 figure

Wisdom of the crowd: insights gained from comparing predicted and observed effects of blood pressure lowering strategies

In a first of its kind assessment in cardiovascular research, we assessed whether pooled cardiovascular expertise could accurately predict efficacy and tolerability for both a novel and an established treatment option. A survey was administered prior to the publication of the QUARTET (A Quadruple UltrA-low-dose tReatment for hypErTension) trial. QUARTET was a multicentre, double-blind, parallel-group, trial that randomised participants to initial treatment with either monotherapy or an ultra-low dose quadruple single pill combination for 12 weeks. Survey participants were asked to predict blood pressure (BP) at 12 weeks and 52 weeks for both groups