119 research outputs found

    变构受体分子的设计及其在分子动态识别中的应用

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    我国电视体育解说发展研究

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    通过文献资料法、调查访问法等,对国内外体育解说的发展现状进行了比较研究。结果发现:目前我国体育解说员的专业素质与迅速发展着的体育赛事以及广大观众的欣赏需求还存在较大差距。提高体育解说员的专业素质已成为此类人才培养最迫切的问题,对2008年北京奥运的顺利举办具有重要的意义。它要求体育解说员具有过硬的政治素质、强烈的敬业精神、多向型的知识结构、冷静敏捷的应变能力、深厚的语言表达功底等

    An Improved PSO Method Based on Adaptive Cognitive Domain

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    为提高粒子群算法的收敛性能,提出一种自适应粒子认知域方法.在粒子位置的更新方法中,粒子运动到当前的最好位置由计算得到的最好位置为中心,粒子的认知方向为导向来确定.利用线性惯性下降权重来实现粒子的优化.为验证该方法的有效性,将此方法应用于3种不同的粒子群方法,分别是固定权重粒子群方法、线性下降权重粒子群方法及阶梯形群体粒子群算法.实验结果表明此方法是较有效的.To improve the convergent performance of particle swarm optimization(PSO),an adaptive cognitive domain particle swarm optimization(ACDPSO)method is proposed.In the updating equations of particles,the current best position,which the particle achieves,is determined by the center of the best calculated position and the cognizant direction of the particle.Linear decreasing inertia weight is used to optimize particles.Three different PSOs,particle swarm with constant weight(CWPSO),linear decreasing inertia weight PSO(LDWPSO)and Ladder PSO(LPSO),are combined with the proposed method to test the performance of the proposed method,and the results indicate that the proposed method is effective.教育部科学技术研究重点项目(No.209057);安徽省自然科学基金项目(No.090412070);高等学校省级优秀青年人才基金项目(No.2009SQRZ088ZD);高等学校省级自然科学研究项目(No.KJ2009B062)资

    LED Color Analysis

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    主要对蓝光、绿光、白光lEd的色度特性进行分析,首先通过单色仪,分别测得蓝光、绿光、白光lEd的相对光谱功率分布并以色度学理论为基础,计算出光源主波长、色纯度、色温和显色指数.计算结果表明:蓝光lEd和绿光lEd主波长随标准光源的不同变化不大,色纯度比较高,分别在0.64和0.87左右,一般显色指数为-29和-14,显色性很差,不适合用来做照明光源.白光lEd主波长随标准光源的不同变化较大,色纯度相当低,接近0,一般显色指数为82,显色性很好,完全符合照明光源的要求.In order to study the color characteristics of light-emitting diode,the characteristics of blue,green and white LED colors are analyzed.Firstly,the spectral power distribution of blue,green,white LED is respectively measured by using the monochromator,and then on the basis of the theory chroma,the main light source wavelength,color purity,color temperature and color rendering index are calculated.The results show that blue LED and green LED dominant wavelengths change little with different standard light sources,and the color purities are relatively high,at 0.64 and 0.87,respectively,the general color-rendering is very poor for the index of-29 and-14,so these blue and green LED are not suitable to be used as lighting source.White LED dominant wavelength largely change with different standard light sources,and color purity is relatively low,near 0,color rendering is good for the general color-rendering index of 82, so white LED is in full conformance with the lighting requirements

    N-(二茂铁酰胺基)硫脲类阴离子受体

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    我们将N-(苯甲酰胺基)硫脲类阴离子识别受体研究拓展至N-(二茂铁酰胺基)硫脲,设计合成了N-(二茂铁甲酰胺基)-N'-(取代苯基)硫脲(3a~3e,取代基X=p-OCH3,p-CH3,H,m-Br,m-CF3),其中二茂铁基系芳香性的电化学活性基团、“—NH—”为连接臂.研究的目的是进一步理解“—NH—”连接臂的特性和3a~3e作为阴离子的电化学响应受体的可行性.我们发现,3a~3e分子中的N'-苯环取代基不影响其半波电位(0.31Vvs.Ag/AgNO3);二茂铁环芳香质子和酰胺基—NH质子的核磁化学位移不受取代基的影响,而N'-苯基芳香质子和硫脲—NH质子的化学位移显著地受制于取代基;说明受体3分子中酰肼基N—N单键高度扭曲,阻碍了N'-苯环取代基电子效应传递至二茂铁基.我们观察到乙腈中3的氧化电位因阴离子如CH3CO-2和F-的结合负移200mV,二茂铁基芳香质子的化学位移向高场移动,意味着阴离子结合诱导了受体3分子中酰肼基N—N单键构型变化,使阴离子结合信息得以传递至二茂铁环.吸收光谱滴定实验表明,乙腈中3a~3e与阴离子结合时在约315nm处出现新的吸收峰,光谱红移达5820cm-1,阴离子如CH3CO-2和F-的结合常数在106mol-1?L,均远高于传统的二苯基硫脲类受体(1);我们还发现,尽管1和3a~3e分子中硫脲—NH质子酸性对取代基的依赖性相近,3a~3e之阴离子结合常数的取代基效应强于1.我们认为,这是由于N—N键的变构作用导致3a~3e的吸收光谱红移、阴离子结合常数和阴离子结合常数的取代基效应远高于传统的N,N'-二苯基硫脲类受体,因而体现了“—NH—”连接臂的独特性质

    布鲁菌病44例临床特征分析

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    目的分析大庆地区44例布鲁菌病患者临床表现及实验室相关指标的变化,为临床诊治提供依据。方法回顾性分析大庆油田总医院2014年2月-2018年8月44例布鲁菌病患者的临床特征。结果大庆地区布鲁菌病患者以农牧民(25例,56.8%)和30岁以上患者(31~69岁,93.2%)为主,临床主要表现为贫血30例(68.2%)、发热23例(52.3%)、胆囊疾病9例(20.5%)、脾肿大9例(20.5%)、胃炎7例(15.9%)、关节炎关节痛6例(13.6%)、睾丸附睾炎4例(9.1%)、心包积液4例(9.1%)、全血细胞减少2例(4.5%)、胸壁脓肿1例(2.3%)。实验室相关指标中,降钙素原(PCT)升高31例(31/32,96.9%),C反应蛋白(CRP)升高33例(33/35,94.3%),红细胞沉降率(ESR)增快11例(11/13,84.6%),44患者中白蛋白减少37例(84.1%),肝功能异常27例(61.4%),单核细胞增多23例(52.3%),白细胞升高10例(22.7%),血小板减少7例(15.9%)。结论布鲁菌病随受累器官不同临床表现多样,除常见症状外,胆囊病变也是其可能出现的临床特征;在实验室相关指标中,可出现单核细胞增多及血小板减少,PCT普遍升高且以轻度升高为主。临床医师应加强对该病的认识,以做到早期诊断和治疗

    The Photoluminescence Properties of Self assembled and Nano sized Silicon Quantum Dots

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    【中文摘要】 用 Si H4 气体的减压 CVD法 ,在氧化硅以及石英基板上自然形成了高密度的 (~ 10 11cm-2 )纳米尺寸的半球状硅晶粒 (硅量子点 ) ,并且对其光学吸收和发光 (Photo- luminescence,PL)特性进行了评价。用表面热氧化了的硅量子点样品 ,在室温条件且在高于 1.2 e V以上的能量范围内观察到了 PL谱。随着量子点尺寸的减少 ,PL谱的光学吸收限移向高能方向。 PL谱的峰值能呈现大幅度的 (约 0 .9e V)斯塔克移动 ,并且 PL谱的强度几乎与温度无关 ,说明发光来自与局域能级相关联的发光和复合过程。 【英文摘要】 Using the low pressure CVD method with SiH 4 gas, we have accumulated the silicon quantum dots in self assembled and nano sized on a silica glass substrate. The optical absorption and photoluminescene spectra have been observed. With decreasing the size of silicon quantum dot, the limit of optical absorption shifts to higher energy. The intensity of photoluminescence spectrum is independent of temperature, which means that the photoluminesce...福建省自然基金资助项

    N-(ferrocamido)thiourea-based anion receptors

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    We extended our research on N-benzamidothiourea based anion receptors to N-ferrocamidothioureas and synthesized N-feffocamido-N'-(substituted phenyl)thioureas (3a similar to 3e, substituent X =p-OCH3, p-CH3, H, m-Br, and m-CF3). In 3a similar to 3e an electrochemically active ferrocene moiety was employed as an aromatic counterpart of phenyl and -NH- was a spacer linking ferrocene signal reporter and the thiourea binding-site. Cyclic voltammetric experiments carried out in acetonitrile indicated that the half-wave potentials of 3a similar to 3e of 0.31 V vs. Ag/AgNO3 were independent of the substituent at N'-phenyl ring. It was found that the H-1 NMR chemical shifts of the aromatic protons at ferrocene moiety and the amido -NH proton in 3 did not, whereas those of the M-phenyl aromatic protons and the thioureido -NH protons did vary when the N'-phenyl substituent was changed. The azino N-N bond was hence concluded to be twisted that blocked the electronic communication between the ferrocene moiety and thiourea anion-binding site. Yet we experimentally observed that the oxidation potentials of 3a similar to 3e shifted by ca. -200 mV in the presence of anions such as CH3CO2- and F- in acetonitrile and the chemical shifts of the ferrocene aromatic protons shifted to high field upon anion binding to the thiourea moiety in 3a similar to 3e. A conformation change in the N-N bond was hence assumed for 3a similar to 3e upon anion binding. Absorption titrations indicated that anion binding to 3a similar to 3e resulted in-a new absorption band at ca. 315 nm with a spectral red-shift of 5820 cm(-1) irrespective of the substituent. The spectral red-shift, anion affinity of 10(6) mol(-1).L orders of magnitude for CH3CO2- and F-, and substituent effect on the anion affinity of 3a similar to 3e were found much higher than those of the corresponding traditional N,N'-diphenylthiourea counterparts (1). It was concluded that anion binding induced conformational change in 3a similar to 3e led to enhanced anion affinity and substituent effect on the anion affinity, information indicative of allosteric character of the receptors and instructive for designing N-arylamido-N'-arylthiourea based anion receptors. Results reported here further supported the advantages of the" NH-" spacer in N-benzamidothiourea-based anion receptors

    忆胡济民先生对近物所的关心

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    <正>胡济民先生离我们而去了,但他为我国原子能科学事业和核物理学的发展所作的贡献深深地留在了我们的心中.特别是他为中科院近代物理研究所重离子加速器工程建设和核物理研究工作的持续发展所给的支持和贡献令我们永远难忘.他是近物所的客座研究员,后来又担任兰州重离子加速器国家实验室学术委员会主任和原子核理论中心的科学顾问.多年来,他经常关心和参加有关近物所的各类学术活动,并给予了有力的支持和指导.胡先生是
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