291 research outputs found

    〔研究ノート〕ヒト血清アルブミンの糖化反応による カルボキシメチルリジンの生成箇所の同定

    Get PDF
      Human serum albumin(HSA)is an abundant plasma protein and is modified by glucose in plasma. The incubation of HSA with glucose at 37℃ for four weeks resulted in the formation of carboxymethyllysine in 11 sites of lysine residues of HSA(65, 190 . . .Ⅰ, 199, 233, 313, 378 . . .Ⅱ, 402, 432, 519, 525, 573 . . . Ⅲ). The same experiments without glucose showed no carboxymethyllysine formation.  Although early studies established that four lysine residues(Lys199, Lys281, Lys439 and Lys525)had been modified by nonenzymatic glycosylation, carboxymethylations of Lys281 and Lys439 were not detected in this experiment. Most carboxymethylation of lysine residues in HSA was located in domain Ⅲ in our study

    シンサイゴ ノ カブカ ジョウショウ キギョウ ノ WEB マイニング ニヨル ゲンイン ブンセキ

    Get PDF
     我々は2011年3月の東日本大震災によって引き起こされた経済活動における事象の記録,震災という未曾有の経済的混乱の状況下での被害状況および復興のようすを,若い世代に伝えたいと考える。その一環として,本稿では意外な株価上昇の原因をwebマイニングにより探るケーススタディについて述べる。震災後,ほとんどの企業が株価下落となったが,大幅に株価が上昇した企業もあった。また,震災の影響でマイナス要因が多いのも関わらず,株価が上昇した企業もあった。我々は,そのような事例として,仙台市の酒のやまや,オリエンタルランドを例にとり,その株価上昇の原因をwebテキストマイニングによって分析した

    野生ルイボスが自律神経機能に与える影響

    Get PDF
    The leaves of rooibos, a plant which only grows in the Republic of South Africa, are used to prepare a non-caffeine herb tea having pharmacological activities. We investigated the effect of rooibos tea on the autonomic nervous function and subjective mood.The subjects, 22 healthy adult females, were given rooibos tea and the following physiological parameters were measured, blood pressure, heart rate at low frequency (LF) and high frequency (HF), and salivary amylase. The profi le of mood states (POMS) test was obtained to analyze the psychological condition, and the Uchida-Kraepelin test was used to load stress for 30 minutes. One control group was given plain hot water and the other, green tea (gyokuro). Rooibos tea significantly reduced salivary amylase activity (p<0.01), and alleviated “Depression-Dejection” in POMS. This suggested that rooibos tea has a relaxation effect towards stress.Analysis of the scent component of rooibos tea leaves by gas chromatography-mass spectrometry (GC/MS) revealed the presence of guaiacol and geranylacetone
    corecore