Material windows and working stations. The discourse networks behind skeuomorphic interface in Pathfinder: Kingmaker

The article probes the intermedial structure of the skeuomorphic interface in Pathfinder: Kingmaker. The author indicates that intermedia research in game studies is often diachronically limited, focusing on material and semiotic interactions between “old” and “new” media. He proposes to open the field onto historically aware discoursive analysis and bases his method on Friedrich Kittler’s notion of “discourse networks”. This allows him to inspect the game in relation to technologically-founded networks that embody or bring into life specific modes of though and experience. During his analysis, he discovers that the interface design is involved with navigation devices in Late Medieval and Early Renaissance periods, Alberti’s windows as objects through with narrative spaces become visible, isometric modes of objective thinking, industrial and cybernetic notions of control, and the Xerox invention of the computer as a working environment.The article probes the intermedial structure of the skeuomorphic interface in Pathfinder: Kingmaker. The author indicates that intermedia research in game studies is often diachronically limited, focusing on material and semiotic interactions between “old” and “new” media. He proposes to open the field onto historically aware discoursive analysis and bases his method on Friedrich Kittler’s notion of “discourse networks”. This allows him to inspect the game in relation to technologically-founded networks that embody or bring into life specific modes of though and experience. During his analysis, he discovers that the interface design is involved with navigation devices in Late Medieval and Early Renaissance periods, Alberti’s windows as objects through with narrative spaces become visible, isometric modes of objective thinking, industrial and cybernetic notions of control, and the Xerox invention of the computer as a working environment

„Dla jednych trutką, a dla innych karmą” – kontestacja w tekstach polskiego hip-hopu

The article deals with the topic of contestation in hip-hop songs. The author goes through historical sources that have created hip-hop and notices that this subculture has been built upon cultural tradition of contestation. This fact allows to include hip-hop in a wider aspect. The analysis of selected examples shows how the subculture in question creates the image and the concept of power. The author observes that the hip-hop subject defines social reality as a cause of imprisonment. The study of rappers’ textual self-creations allows to deduce that they claim to know the only path to freedom. As a result, hip-hop culture is constructed around the dichotomy, exemplified in a division into “us” and “them”. The author detects that hip-hop songs use propaganda language and war stylizations, thus they foreshadow and fight for a total reformation of power scheme

Pasaże tekstowe w polskim hip-hopie. Analiza opisów przestrzeni miejskiej w wybranych tekstach rapowych

Text passagesin Polish hip-hop. An analysis of description of the urban space in selected rap lyricsThe goal of this article was to analyze the issue of how discourse of polish hip-hop describes cities. Mostly polish artist’s lyrics were discussed, they were investigated in the context of the whole hip-hop culture. Article was divided into three main analytic parts. The first one presents, how rappers “read” the city. Analyzed works treat the city space as structure, which expresses deeply hidden substance. The next chapter discusses the ways of representing city, they are considered to be “textual passages” – poetics of such texts is based on discontinuity, it tries to represent dynamics of ever changing space. The last part of article examines the topic of “district”, which in hip-hop is understood as the central space, building foundations of hip-hop’s ontology. This research shows unique coherence of many different texts, that were created in one subculture. Also, this research can be a point of departure for further examination of the presented topics

Parateksty gier cyfrowych – odbiór gry a paratekstualne funkcje i procesy

W artykule zostaje poruszony temat drukowanych paratekstów i cyfrowych gier. Autor wywodzi metodologię badawczą z teorii Gérarda Genetta o transtekstualności, zwracając uwagę na związek paratekstów z próbą autorskiej kontroli recepcji tekstu. Na tej podstawie wyróżnia trzy funkcje paratekstów gier: narracyjną, medialną oraz ekonomiczną. Parateksty pogłębiają narracje oraz światy kreowane przez gry. Definiują medialność gry, konfrontując ją z tekstami o odmiennych od niej właściwościach. Są uwikłane w materialne i rynkowe aspekty produkcji. Funkcje te tworzą sieć wzajemnych zależności, wpływając na recepcję gry. Autor definiuje paratekstualność jako proces, który nie tyle zapośrednicza, co konfiguruje narrację i medialność gry.Żmuda explores the printed paratexts of video games. Drawing on Gérard Genette’s theory of transtextuality, he points out that paratexts are related to authors’ attempts to control the texts’ reception. Three functions of paratexts in games are highlighted, namely the narrative function, the medium-based function, and the commercial function. Paratexts give depth to the narrative and the gameworld. They define the game’s mediality, confronting it with texts that have different properties. They are bound up with the material and market-based aspects of production. These functions give rise to a network of mutual interdependencies that impact a game’s reception. Rzeszowski defines paratextuality as a process that not only mediates the narrative and mediality of a game but also configures it

Reviewing the current treatment approaches for vitiligo – analysis of literature

Introduction: Vitiligo is a relatively common systemic, idiopathic disease within the spectrum of pigmentary disorders. Clinically, it presents as depigmented patches on the skin, resulting from the loss or dysfunction of melanocytes. Despite not impacting life expectancy, vitiligo should not be perceived merely as a cosmetic defect, given its potential to burden daily life and the frequent experiences of stigmatization by patients. Aim of the study: The aim of this study was to summarize the existing knowledge regarding the treatment of vitiligo. The current treatments in practice, alongside potential new methods, were summarized and described. Materials and methods: The literature available in the PubMed database was reviewed using the following keywords: “Vitiligo”, “Vitiligo treatment”, “Vitiligo new treatment methods”, “Targeted therapies for vitiligo”. Conclusions: Vitiligo is a multifactorial and still inadequately understood disorder, leading to a lack of fully safe and effective treatment. As in the management of other diseases, there should be a push for highly personalized treatments for patients. This approach takes into account the differences among patients and ensures a better chance of a positive clinical response. To achieve this goal, it's necessary to explore new treatment methods and expand ongoing research efforts. Also, raising awareness of vitiligo is key to increasing acceptance, support and understanding for those affected by the disease

Platelet-rich plasma - a revolutionary therapeutic option in multi-disciplinary indications

Background: Platelet-rich plasma (PRP) was originally described as a small volume of plasma that contains higher concentrations of platelets, compared to peripheral blood. Although currently the use of PRP in most indications is off-label, it is not prohibited. Initially, PRP was used for wound healing and tissue regeneration in fields such as orthopaedics, dermatology, maxillofacial surgery and dentistry. Aim of the study: The aim of this article was to present and summarise the modern production methods, the mechanism of action at the molecular and biochemical level and the most important uses and indications of PRP in present-day medicine. Material and methods: A cross-sectional search of relevant literature was performed in databases using accepted wording. Publications from 2003-2023 were included. The entire process has been supplemented with additional procedures to increase the reliability of this publication. Results: Orthopaedics has gained many minimally invasive therapeutic solutions thanks to PRP. Its effects on ligament and tendon tissues have been studied, where promising data have been proven. Also in aesthetic medicine and dermatology, many treatment strategies have been developed using PRP, mainly for the treatment of acne, androgenic alopecia and delaying tissue ageing as much as possible. Conclusion: Platelet-rich plasma has found application in the treatment of many conditions in orthopaedics, dermatology, aesthetic medicine and dentistry. It is characterised by good therapeutic efficacy, with relatively low risk. However, high-quality studies are still lacking to provide more reliable data

Cone-beam computed tomography in implant dentistry - guidelines, current concepts and limitations for practice

This article issues scientific background of Cone-beam computed tomography (CBCT) and the importance of taking x-rays before and after implant placement in daily practice as a common care. The review will introduce cone-beam computed tomography guidelines, restrictions and intraoperartive issues for instance nerve damage and bleeding incidents. Modern CBCT technology enables specialists to avoid making a wrong diagnosis, which translates into a higher percentage of people with a positive treatment outcome. Diagnostic radiology is a crucial element of every dental treatment planning. CBCT market is expanding gradually since two decades, there are more than 85 distinct CBCT tools available. CBCT is a three-dimensional (3D) imaging used nowadays in dentistry with increased frequency and offers volumetric data on jaw bones and teeth with relatively low radiation doses and costs. Currently, the greatest advantage of CBCT examinations over radiographs is the fact that the image obtained is presented in a 3D projection and not, as is the case, in 2D. It has the ability to help a wider range of patients, but the use of CBCT also has negative consequences. Routine or excessive use has resulted in increased radiation doses accumulating in the patient's body, which translates into an increased risk of adverse effects. The risk varies according to the age of the patient under study and is directly proportional to it, that is, it is highest for young people and lower for older people. The potential risk is also slightly higher in the female population. For this reason, creating awareness of the mandatory patient safety management of CT scans is a key process by which X-ray exposures can be optimised

Reviewing the current treatment approaches for vitiligo – analysis of literature

Introduction: Vitiligo is a relatively common systemic, idiopathic disease within the spectrum of pigmentary disorders. Clinically, it presents as depigmented patches on the skin, resulting from the loss or dysfunction of melanocytes. Despite not impacting life expectancy, vitiligo should not be perceived merely as a cosmetic defect, given its potential to burden daily life and the frequent experiences of stigmatization by patients. Aim of the study: The aim of this study was to summarize the existing knowledge regarding the treatment of vitiligo. The current treatments in practice, alongside potential new methods, were summarized and described. Materials and methods: The literature available in the PubMed database was reviewed using the following keywords: “Vitiligo”, “Vitiligo treatment”, “Vitiligo new treatment methods”, “Targeted therapies for vitiligo”. Conclusions: Vitiligo is a multifactorial and still inadequately understood disorder, leading to a lack of fully safe and effective treatment. As in the management of other diseases, there should be a push for highly personalized treatments for patients. This approach takes into account the differences among patients and ensures a better chance of a positive clinical response. To achieve this goal, it's necessary to explore new treatment methods and expand ongoing research efforts. Also, raising awareness of vitiligo is key to increasing acceptance, support and understanding for those affected by the disease

Urgent pericardiocentesis is more frequently needed after left circumflex coronary artery perforation

Background: Coronary artery perforation (CAP) is a rare but potentially life-threatening complication of percutaneous coronary interventions (PCIs) due to the risk of cardiac tamponade. Strikingly, in contrast to numerous analyses of CAP predictors, only few studies were focused on the predictors of tamponade after PCI, once iatrogenic CAP has occurred. Our aim was to search for clinical and periprocedural characteristics, including the coronary artery involved, associated with the development of acute cardiac tamponade among patients experiencing CAP. Methods: From the medical records of nine centers of invasive cardiology in southern Poland, we retrospectively selected 81 patients (80% with acute myocardial infarction) who had iatrogenic CAP with a visible extravasation jet during angiography (corresponding to type III CAP by the Ellis classification, CAPIII) over a 15-year period (2005–2019). Clinical, angiographic and periprocedural characteristics were compared between the patients who developed acute cardiac tamponade requiring urgent pericardiocentesis in the cathlab (n = 21) and those with CAPIII and without tamponade (n = 60). Results: CAPIII were situated in the left anterior descending artery (LAD) or its diagonal branches (51%, n = 41), right coronary artery (RCA) (24%, n = 19), left circumflex coronary artery (LCx) (16%, n = 13), its obtuse marginal branches (7%, n = 6) and left main coronary artery (2%, n = 2). Acute cardiac tamponade occurred in 24% (10 of 41), 21% (4 of 19) and 37% (7 of 19) patients who experienced CAPIII in the territory of LAD, RCA and LCx, respectively. There were no significant differences in the need for urgent pericardiocentesis (37%) in patients with CAPIII in LCx territory (i.e., the LCx or its obtuse marginal branches) compared to CAPIII in the remaining coronary arteries (23%) (p = 0.24). However, when CAPIII in the LCx were separated from CAPIII in obtuse marginal branches, urgent pericardiocentesis was more frequently performed in patients with CAPIII in the LCx (54%, 7 of 13) compared to subjects with CAPIII in an artery other than the LCx (21%, 14 of 68) (p = 0.03). The direction of this tendency remained consistent regardless of CAP management: prolonged balloon inflation only (n = 26, 67% vs. 13%, p = 0.08) or balloon inflation with subsequent stent implantation (n = 55, 50% vs. 24%, p = 0.13). Besides LCx involvement, no significant differences in other characteristics were observed between patients according to the need of urgent pericardiocentesis. Conclusions: CAPIII in the LCx appears to lead to a higher risk of acute cardiac tamponade compared to perforations involving other coronary arteries. This association may possibly be linked to distinct features of LCx anatomy and/or well-recognized delays in diagnosis and management of LCx-related acute coronary syndromes