Photoluminescence studies of selected styrylquinolinium thin films made using thermal evaporation deposition technique

In this paper we present a photoluminescence (PL) study of new styrylquinolinium dyes. We made a comparative study of the luminescent properties of thin films grown on quartz substrates using thermal evaporation deposition method. Investigated films show PL emission from the violet to near-IR region at room temperature

High - pressure metal - halogenide lamp with spectral distribution simulating daylight

W niniejszym artykule przedstawiono sprawozdanie z prac nad opracowaniem metodyki kształtowania widma emisyjnego lampy wyładowczej, wysokoprężnej metalohalogenkowej w oparciu o zmianę trzech parametrów, a mianowicie : - dobór napełnienia chemicznego jarznika lampy; - ustalenie optymalnych warunków wyładowania; - dobór materiałów tworzących konstrukcje lampy. W toku realizacji zadania udało się znacznie przybliżyć do optymalnego składu kombinacji metali tworzących napełnienie jarznika, zanalizować procesy zachodzące w łuku wyładowania istotnie wpływające na jego widmo emisyjne oraz określić właściwy rodzaj szkła balonu zewnętrznego lampy. Prace technologiczne, konstrukcyjne i pomiarowe wykonane w trakcie realizacji zadania doprowadziły do wykonania modelu lampy będącej symulatorem światła dziennego kategorii BC, o bardzo dobrym wskaźniku oddawania barw (Ra < 97).The paper presents a report on research work concerning developing methods of shoping the emission spectrum of high pressure metal halide discharge lamp based on variation of the following three parameters: - choice of chemical filling of the are tube , - establishing the optimum discharge conditions, and - choice of materials constituting the lamp structure. During completion of the task the present Authors succeded in obtaining a near optimum composition of metals which the filling of the are tube, in analysing processes occurring in the discharge arc which essentially affect the emission spectrum, as well as in determining the proper kind of the outer baloon glass of the lamp. Technological, design and metrological work carried out in the cours of the task realization lead to developing a model of a lamp simulating daylight of the BC category with a very high colour rendering index (Ra<97)

Innovative housing based light sources electroluminescent intended for the purpose phototherapy neonatal jaundice

W artykule przedstawiono proces opracowania modelu lampy do fototerapii hiperbilirubinemii noworodków na bazie innowacyjnych źródeł światła – diodach elektroluminescencyjnych świecących światłem niebieskim, w odpowiednim, do leczenia żółtaczki noworodków i niemowląt, zakresie widmowym.This article presents a process to develop a model lamp for the phototherapy of the neonatal hyperbilirubinemia. This lamp model is based on innovative sources of light – light-emitting diodes that emit a blue light, that is of an appropriate spectral range for the treatment of the newborn and infant jaundice

Temporin A alone and in combination with imipenem reduces lethality in a mouse model of staphylococcal sepsis.

BACKGROUND: Morbidity and mortality from staphylococcal toxic shock remain high, despite the availability of antibiotics to which the microorganism is sensitive. METHODS: In in vitro experiments, the ability of temporin A to inhibit lipoteichoic acid-induced production of tumor necrosis factor (TNF)- alpha and nitric oxide (NO) was determined. Also, mouse models of staphylococcal sepsis were used to evaluate the efficacy of temporin A alone and in combination with imipenem. BALB/c mice were injected intravenously with live Staphylococcus aureus or heat-killed cells and then received either isotonic sodium chloride solution, 2 mg/kg temporin A, 7 mg/kg imipenem, or 2 mg/kg temporin A in combination with 7 mg/kg imipenem immediately and 6 h after challenge. The main outcome measures were lethality rates, plasma bacterial counts, and plasma TNF- alpha and interleukin (IL)-6 levels. RESULTS: The in vitro experiments showed that temporin A did not cause TNF- alpha or NO release. In the in vivo experiments with live bacteria, both compounds reduced lethality rates and bacterial growth. Imipenem exhibited the highest efficacy. The combination-treated group had significantly lower bacterial counts than did the singly-treated groups and the lowest lethality rates. In the experiments with heat-killed cells, only temporin A demonstrated significant efficacy with respect to lethality and reduction of plasma TNF- alpha and IL-6 levels. DISCUSSION: This study shows that temporin A can reduce the stimulatory effects of bacterial cell components and suggests that it may be beneficial in the treatment of severe staphylococcal sepsis

Effects of pexiganan alone and combined with betalactams in experimental endotoxic shock

To investigate the efficacy of pexiganan, a 22-residue magainin analog, alone and combined with betalactmas antibiotics in three experimental rat models of Gram-negative septic shock. Adult male Wistar rats were given (i) an intraperitoneal injection of 1 mg Escherichia coli 0111:B4 LPS; (ii) 2x10(10)CFU of E. coli ATCC 25922; and (iii) intra-abdominal sepsis induced via cecal ligation and puncture. For each model, all animals were randomized to receive intraperitoneally isotonic sodium chloride solution, 1 mg/kg pexiganan, 1 mg/kg polymyxin B, 20 mg/kg imipenem, 60 mg/kg piperacillin alone and combined with 1 mg/kg pexiganan. Each group included 15 animals. Lethality, bacterial growth in blood or intra-abdominal fluid, endotoxin and TNF-alpha concentrations in plasma. All compounds reduced the lethality when compared to controls. Piperacillin and imipenem significantly reduced the lethality and the number of E. coli in abdominal fluid compared with saline treatment. Pexiganan showed a slightly lower antimicrobial activity than betalactams even though it achieved a substantial higher decrease in endotoxin and TNF-alpha plasma concentrations than imipenem and piperacillin. No statistically significant differences were noted for antimicrobial and antiendotoxin activities between pexiganan and polymyxin B. Combination between pexiganan and betalactams showed to be the most effective treatment in reducing all variables measured. The use of a novel antimicrobial compound able to bind to LPS associated to potent antibiotics such as betalactams may become an important future consideration for sepsis treatment

Observation of new h9/2 and h11/2 bands in 187T1

The unfavoured signature of the rotation-aligned band associated with the prolate h9/2 structure in 187T1 has been identified. The deformation-aligned 11/2−[505] band is also confirmed and extended. While the alignment properties of the 11/2−[505] band seem to indicate that it has a similar magnitude of deformation as the prolate 186Hg core, the signature splitting at low spin, taken together with new self-consistent calculations, suggest that it may actually be triaxial with γ ≈ −180 near the bandhead