Predictors of adverse perinatal outcomes in intrahepatic cholestasis of pregnancy

Objectives: Our objective was to evaluate in our clinic the perinatal outcomes of patients diagnosed with ICP based on pre-treatment maternal serum bile acid levels, attempt to identify the risk group and review the literature in light of this information.  Material and methods: In total, 370 patients diagnosed with ICP were included in the study, divided into two groups based on the fasting total serum bile acid level before UDCA (Group 1: 10 ≥ 40 μmol/L, and Group 2: ≥ 40 μmol/L). The groups were examined for clinical characteristics and pregnancy outcomes.  Results: It was found that preterm delivery and neonatal intensive care need increased at a serum bile acid cut-off value of 34 μmol/L. Regardless of serum bile acid, significantly higher rates of meconium-stained amniotic fluid and foetal distress were observed in patients whose diagnoses were made before 34 weeks of gestation.  Conclusions: Foetal complications over 40 μmol/L of serum bile acid were significantly increased. However, slightly lower levels cut-off values (34 μmol/L) were obtained in terms of preterm birth and neonatal intensive care need. The incidence of meconium-stained amniotic fluid and foetal distress was higher in patients whose diagnosis were made before 34 weeks of gestation.

Enriching Pre-service Teacher Education with Keeping Learning Journals

Investigating the integration of learning journals into a pre-service teacher education course to promote reflection was the overall goal of this study. Studies about evaluating students’ journals have generally analyzed them using a holistic and general approach without examining their content and levels of reflection. This study focuses on both contents, levels of reflection, and their relationship. The participants of the study consisted of 33 senior pre-service elementary teachers. The participants were asked to produce a learning journal entry each week at the end of the Science, Technology, Society, and Environment class, in which they were asked to reflect on what they had learned. A deductive content analysis was utilized to determine the levels of reflection of the pre-service teachers’ journals. Deductive content analysis was used to determine the levels of reflection of the pre-service teachers’ journals. The levels of reflection of the participants were moderate and did not show a pattern of improvement over time; instead, the levels of reflection depended on the content of the related class meeting. The majority of the participants agreed that keeping learning journals improved their self-expression and self-assessment skills and retention. The feedback cycle should be reconsidered for further improvement in the journals

Fabric defect detection using linear filtering and morphological operations

An algorithm with linear filters and morphological operations has been proposed for automatic fabric defect detection. The algorithm is applied off-line and real-time to denim fabric samples for five types of defects. All defect types have been detected successfully and the defective regions are labeled. The defective fabric samples are then classified by using feed forward neural network method. Both defect detection and classification application performances are evaluated statistically. Defect detection performance of real time and off-line applications are obtained as 88% and 83% respectively. The defective images are classified with an average accuracy rate of 96.3%

Application of Neural Networks (NNs) for Fabric Defect Classification

The defect classification is as important as the defect detection in fabric inspection process. The detected defects are classified according to their types and recorded with their names during manual fabric inspection process. The material is selected as “undyed raw denim” fabric in this study. Four commonly occurring defect types, hole, warp lacking, weft lacking and soiled yarn, were classified by using artificial neural network (ANN) method. The defects were automatically classified according to their texture features. Texture feature extraction algorithm was developed to acquire the required values from the defective fabric samples. The texture features were assessed as the network input values and the defect classification is obtained as the output. The defective images were classified with an average accuracy rate of 96.3%. As the hole defect was recognized with 100% accuracy rate, the others were recognized with a rate of 95%

2,4-Dibromo-2,3-dihydro-1H-inden-1-yl acetate

In the title compound, C11H10Br2O2, the cyclo­pentene ring fused to the benzene ring adopts an envelope conformation, with the C atom attached to the Br atom as the flap. The crystal structure does not exhibit any classical hydrogen bonds. The mol­ecular packing is stabilized by van der Waals forces and π–π stacking inter­actions with a centroid–centroid distance of 3.811 (4) Å

Ultrazvučna procjena debljine femoralne hrskavice u osobba s asimptomaskom hiperuricemijom: istraživanje s kontrolnom skupinom

The aim was to evaluate the effect, if any, of asymptomatic hyperuricemia on distal femoral cartilage thickness through musculoskeletal ultrasonography. A total of 66 participants were evaluated in this prospective, controlled study, including 33 asymptomatic hyperuricemic patients who presented at our outpatient clinic between January and April 2020, and 33 normouricemic subjects matched for age, gender and body mass index. Participants with systemic diseases affecting uric acid level such as chronic renal failure, psoriasis, gout, etc., participants using drugs that can affect uric acid level, and those with knee complaints were excluded from the study. Cartilage thickness measurements were taken using musculoskeletal ultrasonography from the right medial condyle, right lateral condyle, right intercondylar area, left medial condyle, left lateral condyle and left intercondylar area. Distal femoral cartilage thickness was lower in all measurement areas in the asymptomatic hyperuricemia group than in the normouricemic group (p<0.05 all). No correlation was noted between uric acid levels and cartilage thickness in all measurement areas in either the asymptomatic hyperuricemic or normouricemic group (p>0.05 all). We think that distal femoral cartilages seem to be thinner in participants with asymptomatic hyperuricemia. Longitudinal studies are needed to determine whether asymptomatic hyperuricemia will lead to knee osteoarthritis in individuals, although we believe that people with asymptomatic hyperuricemia should be informed accordingly in order to prevent development of potential knee osteoarthritis.Cilj istraživanja bio je procijeniti učinak, ako postoji, asimptomatske hiperuricemije na debljinu distalne femoralne hrskavice pomoću mišićno-koštanog ultrazvuka. U ovom prospektivnom kontroliranom istraživanju sudjelovalo je ukupno 66 osoba, uključujući 33 bolesnika s asimptomatskom hiperuricemijom koji su došli u našu ambulantu između siječnja i travnja 2020. godine i 33 osobe s normouricemijom podjednake dobi, spola i indeksa tjelesne mase. Isključene su bile osobe sa sistemskim bolestima koje utječu na razinu mokraćne kiseline, kao što su kronično bubrežno zatajenje, psorijaza, giht itd., osobe koje uzimaju lijekove koji mogu utjecati na razinu mokraćne kiseline te oni s tegobama u koljenu. Debljina hrskavice mjerena je pomoću mišićno-koštanog ultrazvuka u desnom medijalnom kondilu, desnom lateralnom kondilu, desnom interkondilarnom području, lijevom medijalnom kondilu i lijevom interkondilarnom području. Debljina distalne femoralne hrskavice bila je niža na svim mjernim mjestima u skupini osoba s asimptomatskom hiperuricemijom u usporedbi sa skupinom osoba s normouricemijom (p<0,05 sve). Nije zabilježena korelacija između razina mokraćne kiseline i debljine hrskavice ni na jednom mjernom mjestu niti u skupini s asimptomatskom hiperuricemijom niti u skupini s normouricemijom (p<0,05 sve). Smatramo da su distalne femoralne hrskavice tanje u osoba s s asimptomatskom hiperuricemijom. Potrebna su longitudinalna istraživanja kako bi se utvrdilo hoće li asimptomatska hiperuricemija dovesti do osteoartritisa koljena kod tih osoba, ali vjerujemo da osobe s asimptomatskom hiperuricemijom treba primjereno obavijestiti kako bi se spriječio razvoj mogućeg osteoartritisa koljena

Sakroiliiti taklit eden hodgkin lenfoma: Olgu sunumu]

Musculoskeletal syndromes may be associated with neoplastic diseases. We hereby report a case of sacroiliitis that was diagnosed as Hodgkin's lymphoma during the follow-up process. Though sacroiliitis was confirmed with magnetic resonance imaging (MRI), a diagnosis of malignancy associated with sacroiliitis may be delayed and cause a clinical challenge. We aimed to discuss the presentation of lymphoma with sacroiliac joint involvement and its probable mechanisms and review the literature

Ureteral Jet Flow Dynamics Can Provide Information About the Mechanism of Stone Formation

Ureteral jet dynamics, which have been shown in recent studies to indicate stone formation mechanism in adults and children, provide information about ureteral peristaltism. The dynamics were measured with Doppler ultrasonography and included ureteral jet flows and ureteral jet patterns. In this paper, we present radiographic images of a non-obstructive lower pole stone in the right kidney and a non-obstructive upper pole stone in the left kidney measuring <1 cm and ureteral jet dynamics in a 26-year-old male patient. Our opinion is that the dynamics can provide information about stone formation mechanism

The effects of Covid-19 on physical medicine and rehabilitation in Turkey in the first month of pandemic

Objectives: The outbreak of novel coronavirus-2019 (COVID-19) has affected Turkey very seriously, as well as all around the world. Many urgent and radical measures were taken due to the high contagious risk and mortality rate of the outbreak. It is noteworthy that isolation recommendations and the provision of health services for pandemic have a negative impact on Physical Medicine and Rehabilitation (PMR) services. In this study, we aimed to evaluate the effects of COVID-19 on the PMR services and physiatrists immediately after the first month of pandemic in Turkey. Patients and methods: An online survey consisting of 45 items was sent to the members of the Turkish Society of Physical Medicine and Rehabilitation. The main goal of the survey was to evaluate the changes in the provided service of PMR and conditions of physiatrists one month after the first reported COVID-19 case in Turkey. Results: A total of 606 PMR specialists and residents responded to the survey. The mean number of the patients visited the outpatient clinics was 148.2 +/- 128.5 per week before the pandemic, it significantly decreased to 23.4 +/- 33.1 per week after the first month of the reported first COVID-19 case. Similarly, the mean number of the patients of inpatient service significantly decreased from 21.7 +/- 39.3 per week to 2.5 +/- 10.0 per week after the first month of the pandemic. Most of the residents (69%) reported that their training was seriously affected due to pandemic. From the economic aspect, 69.2% of the participants who were working at private hospitals reported a decrease in their monthly salary, and 21% of them were sent to an unpaid vacation. A total of 21.9% of private-practice institutions paused their services. During the first month, 46.9% of the participants were assigned to the different services such as COVID-19 inpatient service, emergency or COVID-19 outpatient clinics. According to the Republic of Turkey, Ministry of Health guideline and algorithm, 15.7% of the physicians were in the category of healthcare workers with suspected COVID-19. Conclusion: The COVID-19 pandemic affected seriously both the services and the PMR physicians as early as the first month. This effect is expected to become worse, when the duration of pandemic prolongs. Proper arrangements and measures should be planned to ameliorate the negative effects of the pandemic on the patients and PMR physicians