251 research outputs found
Index of articles 1960-2010
This subject index covers all articles published during the first 50 years of the Quarterly Bulletin (ie up to 2010 Q3). It also includes the main subjects of speeches by the Governors, senior staff and external MPC members, together with notices and notes, including ‘boxes’ in articles and in the various regular commentary articles. It does not include the subject matter of the commentary articles themselves, nor does it cover the statistical annex. Neither does it include the Inflation Report, which was contained within the Quarterly Bulletin during 1993.
The history of the Quarterly Bulletin
This edition marks the 50th anniversary of the Quarterly Bulletin. Over the years, the Bulletin has been one of the main conduits through which the Bank has communicated its thinking to the wider public. This article reviews the history of the Bulletin — both its origins and its subsequent evolution — as well as examining some of the insights that can be gleaned from its pages on some of the key central banking issues of the time.
Living a Healthy Lifestyle
Powerpoint on many aspects of healthy that may be impacted during the first year transition of college.https://digitalcommons.cortland.edu/corslides/1015/thumbnail.jp
Effects of human recombinant growth hormone on exercise capacity, cardiac structure, and cardiac function in patients with adult-onset growth hormone deficiency
Objective Epidemiological studies suggest that adult-onset growth hormone deficiency (AGHD) might increase the risk of death from cardiovascular causes. Methods This was a 6-month double-blind, placebo-controlled, randomised, cross-over trial followed by a 6-month open-label phase. Seventeen patients with AGHD received either recombinant human growth hormone (rGH) (0.4 mg injection daily) or placebo for 12 weeks, underwent washout for 2 weeks, and were then crossed over to the alternative treatment for a further 12 weeks. Cardiac magnetic resonance imaging, echocardiography, and cardiopulmonary exercise testing were performed at baseline, 12 weeks, 26 weeks, and the end of the open phase (12 months). The results were compared with those of 16 age- and sex-matched control subjects. Results At baseline, patients with AGHD had a significantly higher systolic blood pressure, ejection fraction, and left ventricular mass than the control group, even when corrected for body surface area. Treatment with rGH normalised the insulin-like growth factor 1 concentration without an effect on exercise capacity, cardiac structure, or cardiac function. Conclusion Administration of rGH therapy for 6 to 9 months failed to normalise the functional and structural cardiac differences observed in patients with AGHD when compared with a control group
Modelling signaling networks underlying plant defence
Transcriptional reprogramming plays a significant role in governing plant responses to pathogens. The underlying regulatory networks are complex and dynamic, responding to numerous input signals. Most network modelling studies to date have used large-scale expression data sets from public repositories but defence network models with predictive ability have also been inferred from single time series data sets, and sophisticated biological insights generated from focused experiments containing multiple network perturbations. Using multiple network inference methods, or combining network inference with additional data, such as promoter motifs, can enhance the ability of the model to predict gene function or regulatory relationships. Network topology can highlight key signaling components and provides a systems level understanding of plant defence
Markets and operations: 2011 Q4
This article reviews developments in sterling financial markets, including the Bank’s official operations, between the 2011 Q3 Quarterly Bulletin and 25 November 2011. The article also summarises market intelligence on selected topical issues relating to market functioning.
Markets and operations: 2011 Q1
This article reviews developments in sterling financial markets, including the Bank’s official operations, between the 2010 Q4 Quarterly Bulletin and 25 February 2011. The article also summarises market intelligence on selected topical issues relating to market functioning.
Markets and operations: 2011 Q2
This article reviews developments in sterling financial markets, including the Bank’s official operations, between the 2011 Q1 Quarterly Bulletin and 20 May 2011. The article also summarises market intelligence on selected topical issues relating to market functioning.
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A phylogenetic analysis of Orlando Gibbons's Prelude in G
This is the author accepted manuscript. The final version is available from Oxford University Press via http://dx.doi.org/10.1093/em/cau10
The phenotype paradox: lessons from natural transcriptome evolution on how to engineer plants
Plants have evolved genome complexity through iterative rounds of single gene and whole genome duplication. This has led to substantial expansion in transcription factor numbers following preferential retention and subsequent functional divergence of these regulatory genes. Here we review how this simple evolutionary network rewiring process, regulatory gene duplication followed by functional divergence, can be used to inspire synthetic biology approaches that seek to develop novel phenotypic variation for future trait based breeding programs in plants
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