1,460 research outputs found
Polynomial-Chaos-based Kriging
Computer simulation has become the standard tool in many engineering fields
for designing and optimizing systems, as well as for assessing their
reliability. To cope with demanding analysis such as optimization and
reliability, surrogate models (a.k.a meta-models) have been increasingly
investigated in the last decade. Polynomial Chaos Expansions (PCE) and Kriging
are two popular non-intrusive meta-modelling techniques. PCE surrogates the
computational model with a series of orthonormal polynomials in the input
variables where polynomials are chosen in coherency with the probability
distributions of those input variables. On the other hand, Kriging assumes that
the computer model behaves as a realization of a Gaussian random process whose
parameters are estimated from the available computer runs, i.e. input vectors
and response values. These two techniques have been developed more or less in
parallel so far with little interaction between the researchers in the two
fields. In this paper, PC-Kriging is derived as a new non-intrusive
meta-modeling approach combining PCE and Kriging. A sparse set of orthonormal
polynomials (PCE) approximates the global behavior of the computational model
whereas Kriging manages the local variability of the model output. An adaptive
algorithm similar to the least angle regression algorithm determines the
optimal sparse set of polynomials. PC-Kriging is validated on various benchmark
analytical functions which are easy to sample for reference results. From the
numerical investigations it is concluded that PC-Kriging performs better than
or at least as good as the two distinct meta-modeling techniques. A larger gain
in accuracy is obtained when the experimental design has a limited size, which
is an asset when dealing with demanding computational models
Goniothalamus Species: A Source of Drugs for the Treatment of Cancers and Bacterial Infections?
Irrespective of the presence of cytotoxic acetogenins and styryl-lactones in the genus Goniothalamus, only 22 species in the genus Goniothalamus, out of 160 species (13.7%) have so far been investigated. In an effort to promote further research on the genus Goniothalamus which could represent a source of drugs for the treatment of cancers and bacterial infections, this work offers a broad analysis of current knowledge on Goniothalamus species. Therefore, it includes (i) taxonomy (ii) botanical description (iii) traditional medicinal uses and (iv) phytochemical and pharmacological studies. We discuss the molecular mechanisms of actions of acetogenins and styryl-lactones, with some emphasis on the possible involvement of protein kinase, Bax and TRAIL receptors in the cytotoxic effects of styryl-lactones. We also report (v) the growth inhibition of several nosocomial bacteria by Goniothalamus. scortechinii. The crude methanol extract of G. scortechinii showed a good and broad spectrum of antibacterial activity against both Gram-negative and Gram-positive bacteria
Imagining the Body in Pacific Francophone Literature
This article deals with the central position of the body in Polynesian and Kanak imaginary, ancestral myths, and language. In the collective imagination, the body is akin to a particle of the cosmos. The author probes into major primordial images in order to understand the peculiar role of the body in the Oceanic "anthropological structures of the imaginary" (Gilbert Durand’s term) and asks whether the vision proposed by archaic myths finds its way into modern autochthonous Polynesian and Kanak indigenous literature, especially in the writings of Déwé Gorodé, Chantal Spitz, Flora Devatine, and Moetai Brotherson. Indeed, in keeping with the theories of Michel Foucault, the Oceanic body as it appears in modern poetic or novelistic narrations bears witness in its maimed flesh to a collective history and bears the scars of colonialism. Through its transhistorical dimension as well, this brand of francophone literature constitutes an original way to introduce some sort of counter-discourse into narrative strategies shaped by Western colonial history. In reclaiming the body, these writers are also reviving an ancestral voice
Evaluation of Recovery in Female Swimmers During a Competitive Season
Objective: To monitor the stress and recovery of college swimmers throughout a competitive season. The priori hypothesis was that RESTQ-SPORT scores will change with changes in training load through the season Patients or Other Participants: 23 female swimmers (mean age = 19.48±1.16, mean height = 168.6 cm ± 5.5, mean weight = 65.91kg ± 7.78) that were members of a southeastern Division I intercollegiate swim team. Interventions: The training load was measured using session rate of perceived exertion (RPE). RPE uses a 0-10 Borg scale to define effort. Each individual\u27s daily score was multiplied by practice duration to give a training load. The RESTQ-SPORT 76 was given monthly. The data was then placed into the RESTQ-SPORT computer program to calculate scores. Main Outcome Measures: RESTQ-SPORT 76 mean scores for recovery-stress state, global stress, and global recovery were recorded to two decimal places. A repeated measures ANOVA was run on each mean and significance was set at p=0.05. Results: There was a significant time effect for scores over the season (F5=4.67; P\u3c.001) for RESTQ total. A simple contrast using the initial RESTQ-Sport as a baseline (M=9.85 ± 10.34) showed the RESTQ total was significantly less at time point 2 (F1=9.55, M=4.14 ± 10.06 P=.006) and time point 4 (F1=5.88, M=11.65 P=.026). There was no significance for global recovery. Global stress showed a significant time effect for scores over the season (F5=9.85, P\u3c.001). There was no group effect or interaction. A simple contrast using the initial RESTQ-Sport as a baseline (M=19.60 ± 5.71) showed that time point 2 (F1=21.23, M=24.00 ± 6.80 P\u3c.001), time point 4 (F1=20.96, M=26.08 ± 7.72 P\u3c.001), and time point 5 (F1=4.54, M=22.89 ± 7.68 P=.047) were significantly less than baseline. The highest training loads were seen at time points 2 and 4. Conclusions: The study shows that as training load increases through a season, the internal stress increases. This can lead to an increased risk of underrecovery. Swimmers need to be taught better strategies for recovery to gain the intended training effects and improve performance
Evidence of the El Niño/La Niña Climatic Events in New Zealand Over the Last Century
We investigate interrelations between the mean sea level, sea surface temperature, atmospheric temperature and pressure at four tide gauges in New Zealand (Auckland, Wellington, Lyttelton, and Dunedin) with records available for over a century. The least-squares linear regression analysis is applied to estimate linear (secular) trends in the seasonally-adjusted time series. The detrended annual data are then used to analyze the influence of (quasi)periodical climatic cycles on the variability of these recorded data. In particular, we assess the presence of climatic signals attributed to: (i) the inter-annual El Niño Southern Oscillation (ENSO) cycle of El Niño/La Niña events (described by the Southern Oscillation Index - SOI) and (ii) the Inter-decadal Pacific Oscillation (IPO) of the long-term climate cycle occurring over whole Pacific Ocean with a typical period of about 15-30 years. The correlation analysis reveals the presence of significant signal of the SOI and IPO in the mean sea level data in Auckland. The signature of the SOI and IPO attenuates towards higher geographical latitudes. The SOI and IPO also significantly modulate sea surface temperature and atmospheric temperature variations, while the signatures of these climatic cycles are much less pronounced in atmospheric pressure fluctuations
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