118 research outputs found
6-(2,6-Dimethylphenyl)pyrido[2,3-d]pyrimidin-7-amine
Get PDFIn the title compound, C15H14N4, the pyrido[2,3-d]pyrimidine system is almost ideally planar (r.m.s. deviation 0.028 Å) with its mean plane almost orthogonal to the 2,6-dimethylphenyl plane. The dihedral angle formed by these planes [87.3 (2)°] is close to the predicted value (89.7°) obtained by molecular-mechanics force-field calculations. Only one of the two active amine H atoms participates in hydrogen bonding, which links molecules into centrosymmetric dimers
Electrochemical behaviour of dopamine at covalent modified glassy carbon electrode with l-cysteine: preliminary results
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Modeling of G-protein-coupled receptors: application to dopamine, adrenaline, serotonin, acetylcholine, and mammalian opsin receptors
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Development of a Binding Model to Protein Tyrosine Kinases for Substituted Pyrido[2,3- d
No full textTyrosine Kinase Inhibitors. 11. Soluble Analogues of Pyrrolo- and Pyrazoloquinazolines as Epidermal Growth Factor Receptor Inhibitors: Synthesis, Biological Evaluation, and Modeling of the Mode of Binding
No full textQuantitative structure-affinity/selectivity relationship analysis on three-dimensional models of the complexes between the ETA and ETB receptors and C-terminal endothelin hexapeptide antagonists
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