Limb-Darkened Radiation-Driven Winds from Massive Stars

We calculated the influence of the limb-darkened finite disk correction factor in the theory of radiation-driven winds from massive stars. We solved the 1-D m-CAK hydrodynamical equation of rotating radiation-driven winds for all three known solutions, i.e., fast, \Omega-slow and \delta-slow. We found that for the fast solution, the mass loss rate is increased by a factor \sim 10%, while the terminal velocity is reduced about 10%, when compared with the solution using a finite disk correction factor from a uniformly bright star. For the other two slow solutions the changes are almost negligible. Although, we found that the limb darkening has no effects on the wind momentum luminosity relationship, it would affect the calculation of synthetic line profiles and the derivation of accurate wind parameters.Comment: Accepted for publication in ApJ. 19 pages, 6 figure

Flavoprotein monooxygenases for oxidative biocatalysis: recombinant expression in microbial hosts and applications

External flavoprotein monooxygenases comprise a group of flavin-dependent oxidoreductases that catalyze the insertion of one atom of molecular oxygen into an organic substrate and the second atom is reduced to water. These enzymes are involved in a great number of metabolic pathways both in prokaryotes and eukaryotes. Flavoprotein monooxygenases have attracted the attention of researchers for several decades and the advent of recombinant DNA technology caused a great progress in the field. These enzymes are subjected to detailed biochemical and structural characterization and some of them are also regarded as appealing oxidative biocatalysts for the production of fine chemicals and valuable intermediates toward active pharmaceutical ingredients due to their high chemo-, stereo-, and regioselectivity. Here, we review the most representative reactions catalyzed both in vivo and in vitro by prototype flavoprotein monooxygenases, highlighting the strategies employed to produce them recombinantly, to enhance the yield of soluble proteins, and to improve cofactor regeneration in order to obtain versatile biocatalysts. Although we describe the most outstanding features of flavoprotein monooxygenases, we mainly focus on enzymes that were cloned, expressed and used for biocatalysis during the last yearsFil: Ceccoli, Romina Denis. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Rosario. Instituto de Biología Molecular y Celular de Rosario. Universidad Nacional de Rosario. Facultad de Ciencias Bioquímicas y Farmacéuticas. Instituto de Biología Molecular y Celular de Rosario; ArgentinaFil: Bianchi, Dario Alejandro. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Rosario. Instituto de Química Rosario. Universidad Nacional de Rosario. Facultad de Ciencias Bioquímicas y Farmacéuticas. Instituto de Química Rosario; ArgentinaFil: Rial, Daniela Veronica. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Rosario. Instituto de Biología Molecular y Celular de Rosario. Universidad Nacional de Rosario. Facultad de Ciencias Bioquímicas y Farmacéuticas. Instituto de Biología Molecular y Celular de Rosario; Argentin

Las UCPs: una nueva vía para el tratamiento de la obesidad

Los avances recientes en el conocimiento de los mecanismos que controlan el peso corporal han de llevar al desarrollo de nuevas terapias para el tratamiento de la obesidad. En el presente artículo se describe cómo el descubrimiento de la UCP2 y UCP3, dos proteínas desacoplantes que permiten disminuir la eficiencia energética de la respiración mitocondrial, puede llevar al diseño de fármacos que estimulen directamente la quema del exceso de calorías aportadas por la diet

A method to deconvolve stellar rotational velocities

Rotational speed is an important physical parameter of stars and knowing the distribution of stellar rotational velocities is essential for the understanding stellar evolution. However, it cannot be measured directly but the convolution of the rotational speed and the sine of the inclination angle, $v \sin i$. We developed a method to deconvolve this inverse problem and obtain the cumulative distribution function (CDF) for stellar rotational velocities extending the work of Chandrasekhar & M\"unch (1950). This method is applied a) to theoretical synthetic data recovering the original velocity distribution with very small error; b) to a sample of about 12.000 field main--sequence stars, corroborating that the velocity distribution function is non--Maxwellian, but is better described by distributions based on the concept of maximum entropy, such as Tsallis or Kaniadakis distribution functions. This is a very robust and novel method that deconvolve the rotational velocity cumulative distribution function from a sample of $v \sin i$ data in just one single step without needing any convergence criteria.Comment: Accepted in A&

Proyectos Superpuestos. Topografia y paisaje en el campus universitario de Vigo

Ese trabajo se basa en el análisis de las propuestas para el Campus de la Universidad de Vigo (Lagoas – Marcosende), demonstrando como se relacionan entre si y los usuarios, por medio de la topografía y el paisaje locales y verificando si esa interacción funciona como lugar arquitectónico. Se parte del interés despertado por la construcción continuada del sitio, por diferentes autores y con abordajes proyectivos muy distintos. La superposición de las construcciones, aquí divididas en etapas (la primera se caracteriza por la implantación de edificaciones más o menos desconectadas; la segunda por la incipiente articulación de un núcleo estructurante; la tercera, de un plan lineal estructurado, añadido de equipamientos esenciales al crecimiento de la universidad y recientemente construido; una cuarta, que conecta entre el tejido edificado y los equipamientos previstos, cuya construcción se iniciará brevemente) promueve un encuentro arquitectónico de estilos y escuelas, como la gallega, la catalana, la italiana y la paulista

Estratégias de intervenção em diferentes escalas

Neste artigo, procura-se apresentar resultados de investigação doutoral sobre a modalidade de projeto de redesenho. Nela, foram compreendidos alguns mecanismos pelos quais territórios, cidades, bairros e edifícios respondem ao redesenho de seus sistemas internos e interações. Pautada pela análise de contextos urbanos e obras, foi proposta uma abordagem de projetos de intervenção. Delineada por critérios geográficos, técnicos e sociais, apresentam-se resultados sobre estratégias identificadas em casos de estudo. Primeiro, aprendeu-se sobre algumas tentativas de redesenho em contextos urbanos; num segundo momento, entendeu-se como projetos de redesenho funcionam respeito sua paisagem urbana, entorno imediato e nos processos internos da obra intervinda. Finalmente, dividiram-se estratégias entre urbanísticas e arquitetônicas no intuito de evidenciar mecanismos pelos quais o caso estudado articula estas dimensões. O artigo expõe ainda como tais resultados traduzem-se ao interior do objeto teórico a ser redesenhado e a abordagem se desdobra como metodologia.In this article, we seek to provide doctoral research results, concerning the type of redesign project. In it, we understood mechanisms by which regions, cities, neighborhoods and buildings respond to redesign of internal systems and interactions. Guided by analysis of urban and construction contexts, it proposed an approach to intervention projects. Delineated by geographic, technical and social criteria, are presented results on strategies identified in case studies. First, was learned about some attempts to redesign in urban contexts; secondly, was understood as redesign projects work about its urban landscape, immediate surroundings and the internal processes of the work intervened. Finally, were divided into strategies of urban design and architecture in order to highlight mechanisms by which the case study articulates these dimensions. The article explores how such results are reflected in the interior of the theoretical object to be redesigned and the approach unfolds as methodology

ANALISIS PENGARUH KUALITAS KEHIDUPAN KERJA TERHADAP KOMITMEN ORGANISASI DAN KEPUASAN KERJA SERTA DAMPAKNYA TERHADAP KINERJA KARYAWAN BANK MANDIRI BANDA ACEH

ABSTRAKAbstrak Karya Akhir diserahkan kepada Panitia Komisi Ujian untuk mendapatkan Gelar Magister Manajemen pada Program Pascasarjana Universitas Syiah KualaANALISIS PENGARUH KUALITAS KEHIDUPAN KERJA TERHADAP KOMITMEN ORGANISASI DAN KEPUASAN KERJA SERTA DAMPAKNYA TERHADAP KINERJA KARYAWAN BANK MANDIRI BANDA ACEHOlehRIAL ADRIANNIM : 1609200020105Konsentrasi : Manajemen UmumPembimbing Utama : Prof. Dr. Nasir, S.E., MBAPembimbing Pembantu : Dr. Sulaiman, S.E., MMTujuan riset ini adalah untuk mengidentifikasi seberapa besar pengaruh kualitas kehidupan kerja terhadap komitmen dan kepuasan kerja serta dampaknya terhadap kinerja karyawan Bank Mandiri Area Banda Aceh. Riset ini ditujukan pada pegawai pada Bank Mandiri yang menjalankan kegiatan bisnisnya di Kota Banda Aceh. Jumlah populasi adalah 143 orang pegawai, dan menggunakan metode sensus sehingga respondennya adalah seluruh populasi. Structural Equation Modeling (SEM) diaplikasikan sebagai alat analisis. Hasil memperliharkan bahwa komitmen organisasi dan kepuassan kerja dipengaruhi oleh kualitas kehidupan kerja (KKK), namun KKK tidak mempengaruhi kinerja pegawai. Faktor komitmen organisasi ternyata juga tidak mempengaruhi kinerja, namun kinerja karyawan mampu dipengaruhi oleh faktor kepuasan kerja secara positif dan signifikan. Jadi, hanya faktor kepuasan kerja yang berperan sebagai parsial mediator diantara hubungan KKK dan kinerja pegawai.Kata kunci:Kualitas Kehidupan Kerja, Komitmen Organisasi, Kepuasan Kerja, dan Kinerja Pegawai. ABSTRACTAbstract of Final Paper Submitted to The Examination Committe in partial fulfilment of the requirements for the degree of Master of Management on Graduate Program of Syiah Kuala UniversityANALYSIS OF THE EFFECT OF QUALITY OF WORK LIFE ON ORGANIZATIONAL COMMITMENT AND JOB SATISFACTION AND ITS IMPACT ON BANK MANDIRI BANDA ACEH EMPLOYEE PERFORMANCE ByRIAL ADRIANNIM : 1609200020105Specialization :Prof. Dr. Nasir, S.E., MBACo-Supervisor:Dr. Sulaiman, S.E., MMThe initial aims of this study are to determine how the effect of work life quality on organizational commitment, and job satisfaction; its subsequently on the performance of bank employees. This study is conducted in Bank Mandiri operating in the city of Banda Aceh. The population in this study is 143 employees, and it uses the census method so that the sample is the entire population. The statistical tool employed is Structural Equation Modeling (SEM). Finding shows that the quality of work life quality has a positive and significant effect on organizational commitment and job satisfaction; however, it does not impact on employee performance. Organizational commitment also does not affect employee performance; however, job satisfaction positively and significantly affects employee performance. Thus, job satisfaction factor acts as a partial mediator between the influences of work life quality on employee performance.Keywords:Quality of Work Live, Organizational Commitment, Job Satisfaction, and Employee Performance