2,373 research outputs found

    On numerically accurate finite element

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    A general criterion for testing a mesh with topologically similar repeat units is given, and the analysis shows that only a few conventional element types and arrangements are, or can be made suitable for computations in the fully plastic range. Further, a new variational principle, which can easily and simply be incorporated into an existing finite element program, is presented. This allows accurate computations to be made even for element designs that would not normally be suitable. Numerical results are given for three plane strain problems, namely pure bending of a beam, a thick-walled tube under pressure, and a deep double edge cracked tensile specimen. The effects of various element designs and of the new variational procedure are illustrated. Elastic-plastic computation at finite strain are discussed

    Progress in mixed Eulerian-Lagrangian finite element simulation of forming processes

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    A review is given of a mixed Eulerian-Lagrangian finite element method for simulation of forming processes. This method permits incremental adaptation of nodal point locations independently from the actual material displacements. Hence numerical difficulties due to large element distortions, as may occur when the updated Lagrange method is applied, can be avoided. Movement of (free) surfaces can be taken into account by adapting nodal surface points in a way that they remain on the surface. Hardening and other deformation path dependent properties are determined by incremental treatment of convective terms. A local and a weighed global smoothing procedure is introduced in order to avoid numerical instabilities and numerical diffusion. Prediction of contact phenomena such as gap openning and/or closing and sliding with friction is accomplished by a special contact element. The method is demonstrated by simulations of an upsetting process and a wire drawing process

    On the auditory system: genes, DNA repair and ion channel

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    Berekening van stemgrafieken van een luid- of carillonklok

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    Aggression: Its association with dysfunctional thought control processes, cognition, and personality

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    Het hebben van agressieve fantasieën is zo gek nog niet. Marleen Nagtegaal onderzocht vrouwelijke en mannelijke studenten, mannelijke leden van een schietsportvereniging, mannelijke gedetineerden en deelnemers aan controlegroepen. Iedereen heeft agressieve fantasieën. Of ze ook omslaan in agressief gedrag, hangt af van wat er met de gedachten wordt gedaan: worden ze onderdrukt of wordt er bijvoorbeeld over gepraat? Nagtegaal promoveert vrijdag 29 februari 2008 aan de Erasmus Universiteit Rotterdam. Het hebben van agressieve fantasieën an sich doet er niet zo toe, aldus Marleen Nagtegaal. Het komt immers bij iedereen voor. Het is belangrijker wat je vervolgens doet met deze gedachten. Als je afleiding zoekt voor het hebben van agressieve fantasieën of als je hierover praat, heb je minder kans agressief gedrag te vertonen. Probeer je de gedachten te onderdrukken, bestraf je jezelf of ga je over zo’n gedachte piekeren, dan is de kans groter dat je agressief gedrag gaat vertonen

    Why Do Employers (Fail to) Hire People with Disabilities? : A Systematic Review of Capabilities, Opportunities and Motivations.

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    Purpose To increase the number of people with disabilities in employment, we need to understand what influences employers’ hiring decisions. In this systematic review, we map out factors affecting employers’ hiring decisions about people with disabilities. Methods This study is a systematic review that applies the COM-B model to identify factors that contribute to employers (not) hiring people with disabilities. The COM-B model proposes that employers will perform hiring behavior (B) if they have the capability (C), opportunity (O) and motivation (M) to do so. We also investigate if factors have a negative, positive or no effect. We report in accordance with the PRISMA guidelines. Results In a review of 47 studies, we find 32 factors. Most of these factors are barriers. The most frequently mentioned barriers are employers’ (1) expectations that people with disabilities are unproductive, (2) expectations that people with disabilities cost a lot of money, and employers’ (3) lack of knowledge about disabilities. The most researched facilitators for employers to hire people with disabilities include (1) the motivation to help others, (2) working in a large organization, and (3) expecting a competitive advantage. The effect of factors can differ depending on contextual circumstances, including the type of organization, the type of disability and different policies. Conclusions We conclude that hiring decisions are influenced by an array of different barriers and facilitators. The effect of these factors can differ across organizations and disability types. Our study of factors affecting hiring can be used by scholars, policy makers, and organizations to create interventions to increase the hiring of people with disabilities

    Origin and outcome of metastatic tumours to the testes:a nationwide study

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    ObjectivesTo perform a retrospective cohort analysis for metastatic tumours in the testes to explore the timing, presentation and prognosis of this particular type of metastases and the factors that influence outcome.Patients and methodsA nationwide retrospective review of pathology reports of patients with pathologically confirmed metastases to the testis between 1991 and 2021 was performed. Data were collected from the Dutch nationwide pathology databank (PALGA) and the Netherlands Cancer Registry. Log-rank testing and Kaplan–Meier analyses were used to assess overall survival (OS), and Cox proportional hazard models were used for multivariate survival analysis.ResultsA total of 175 patients with a testicular metastasis were included. The median (range) age at diagnosis of testicular metastasis was 67 (3–88) years. Testicular metastases originated from a variety of primary tumours, although most frequently from the prostate (40.6%), kidney (13.7%), colon (10.3%), bladder (7.4%) and skin (5.7%). Synchronous testicular metastasis was detected in 53 cases, while 114 metachronous lesions were found after a median (interquartile range) interval of 22 (1–53) months after the original cancer diagnosis. OS after the diagnosis of a testicular metastasis was poor, with a median survival of 14.2 months (95% confidence interval 10.2–18.3). Primary tumour origin was an independent factor for survival, with worst survival for patients with primary skin, bladder and colon cancer.ConclusionTesticular metastases are very uncommon and arise mainly from primary tumours anatomically close to the testes. Most patients develop metachronous testicular metastasis at an oligometastatic disease stage. These metastases are invariably associated with poor survival
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