Goldman Sachs Investment Report

This presentation is an investment report of Goldman Sachs. It takes a position on the future of the company and explains the reasoning

Life Stories in Context: Using the Three-Sphere Context Model To Analyze Amos's Narrative

Despite a wide theoretical consensus among narrative researchers about the importance of referring to context in analyzing narratives, it seems that the various contexts at work in individual life stories and the specific methodological implications of the importance of context are not that clear. In this paper, I will describe a model for context analysis, which refers to three distinct spheres of contexts in which narrators situate their life stories (Zilber, Tuval-Mashiach, & Lieblich, 2008). The first context involves the immediate inter-subjective relationships within and involving which a narrative is produced; the second comprises the collective social field in which a life and story have evolved; and the third surrounds the systems of broad cultural meaning or meta-narratives that underlie and give sense to any particular life story. In the second part of the paper, I will illustrate the three contexts in Amos's story, and claim that viewing his story as it is embedded through these three contexts not only situates it within a more general social framework, but also enables a deeper understanding of his identity and the core themes of his life-story

Sampling versus Random Binning for Multiple Descriptions of a Bandlimited Source

Random binning is an efficient, yet complex, coding technique for the symmetric L-description source coding problem. We propose an alternative approach, that uses the quantized samples of a bandlimited source as "descriptions". By the Nyquist condition, the source can be reconstructed if enough samples are received. We examine a coding scheme that combines sampling and noise-shaped quantization for a scenario in which only K < L descriptions or all L descriptions are received. Some of the received K-sets of descriptions correspond to uniform sampling while others to non-uniform sampling. This scheme achieves the optimum rate-distortion performance for uniform-sampling K-sets, but suffers noise amplification for nonuniform-sampling K-sets. We then show that by increasing the sampling rate and adding a random-binning stage, the optimal operation point is achieved for any K-set.Comment: Presented at the ITW'13. 5 pages, two-column mode, 3 figure

Malnutrition in Surgical Wards: A Plea for Concern

Background. Malnutrition in hospitalized patients is underdiagnosed, with 30 to 60% of patients admitted being malnourished. The objective of this study was to investigate the nutritional status of patients in a general surgery ward and to define the correlation between the risk of malnutrition and the hospital course and clinical outcome. Study design. The study group included 100 consecutive patients admitted to a general surgery ward who were ambulant and could undergo the Malnutrition Universal Screening Tool (MUST). Results. Thirty-two patients (33%) had aMUST score of 2 or higher, and were therefore defined at high-malnutrition risk. The patients at risk had longer hospitalization and worse outcome. The length of stay of the malnourished patients was significantly longer than that of patients without malnutrition risk (18.8 ± 11.5 vs. 7 ± 5.3 days, P = .003). Mortality in the high-risk group was higher overall, in hospital, and after six months and one year of followup. Conclusions. Medical personnel must be aware that malnutrition afflicts even patients whose background is not suggestive of malnutrition. Best results are achieved when cooperation of all staff members is enlisted, because malnutrition has severe consequences and can be treated easily

Links between core promoter and basic gene features influence gene expression

<p>Abstract</p> <p>Background</p> <p>Diversity in rates of gene expression is essential for basic cell functions and is controlled by a variety of intricate mechanisms. Revealing general mechanisms that control gene expression is important for understanding normal and pathological cell functions and for improving the design of expression systems. Here we analyzed the relationship between general features of genes and their contribution to expression levels.</p> <p>Results</p> <p>Genes were divided into four groups according to their core promoter type and their characteristics analyzed statistically. Surprisingly we found that small variations in the TATA box are linked to large differences in gene length. Genes containing canonical TATA are generally short whereas long genes are associated with either non-canonical TATA or TATA-less promoters. These differences in gene length are primarily determined by the size and number of introns. Generally, gene expression was found to be tightly correlated with the strength of the TATA-box. However significant reduction in gene expression levels were linked with long TATA-containing genes (canonical and non-canonical) whereas intron length hardly affected the expression of TATA-less genes. Interestingly, features associated with high translation are prevalent in TATA-containing genes suggesting that their protein production is also more efficient.</p> <p>Conclusion</p> <p>Our results suggest that interplay between core promoter type and gene size can generate significant diversity in gene expression.</p

Distress Levels among Parents of Active Duty Soldiers during Wartime

Objective: Military service is a highly stressful period both for the soldiers serving and for their parents. Surprisingly, parents’ experience has been mostly ignored in the research. This study’s goal is to shed light on the experience and distress levels of parents of active duty combat soldiers during Operation Protective Edge, a military operation carried out by the Israel Defense Forces during July and August of 2014.Methods: During the advanced stages of the operation, 69 parents of Israeli male combat soldiers (55 mothers and 14 fathers) completed an online survey measuring symptoms of Posttraumatic Stress Disorder (PTSD-Checklist-5) and distress (Brief Symptom Inventory-18). Participants were recruited using a convenience sample, by posting ads on the public Facebook pages of the researchers and of the groups dedicated to parents of Israeli soldiers.Results: Parents’ depression and anxiety symptom levels were higher than depression and anxiety symptom levels of the adult community norms in Israel. General distress rates of parents were similar to those presented by adults in southern Israel who were exposed for 7 years to the ongoing threat of daily rocket fire from Gaza, and higher than rates of a non-threatened Israeli population. Finally, 20.2% of the parents presented PTSD-like symptoms, a higher percentage than the probable PTSD diagnosis rates that were found in the general population in Israel during previous terror waves.Conclusion: This study provides preliminary evidence of soldiers’ parents’ distress and indicates the need for a better understanding of the impact of military service on soldiers’ parents