540 research outputs found
The Place of the Mihanović Psalter in the Fourteenth-Century Revisions of the Church Slavonic Psalter
Modern scholarship on the textual history of Church Slavonic biblical translation recognizes two distinct revisions of the Church Slavonic Psalter from the early fourteenth century, Redaction III (sometimes called the ‘Athonite’ redaction) and Redaction IV, known only in the Norov psalter manuscript. Although they are both attested from the same period and in manuscripts of similar Bulgarian provenance, these two redactions are in some respects systematically different in their linguistic character, their approach to translational issues and their Greek textual basis. In the light of A.A. Turilov’s observation that the Mihanović Psalter, possibly the earliest witness to Redaction III, is written in the same hand as the greater part of the Norov Psalter, this paper examines the textual antecedents of the two redactions and the importance of the Mihanović Psalter as a link between them
The Textual Tradition of the Oxford Serbian Psalter MS e Mus.184
Author Institution: Oxford Universit
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Assessing the Effect of Photodynamic Therapy on Peripheral Nerve and Cancer Cells Using a Thin Tissue Engineered Collagen Culture Model
Abstract not available
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Intracellular localisation of mTHPC and effect of photodynamic therapy in cells of the mammalian peripheral nervous system
Fewer nerve-related side effects have been noted after treating head and neck cancer with photodynamic therapy (PDT) compared to conventional cancer therapy. Our aim is to investigate the biological basis for any such nerve-sparing effect. In this study the intracellular localisation and effect on cell viability of the photosensitiser meta-tetrahydroxylphenylchlorin (mTHPC) was investigated in cell culture models using peripheral nerve cells.
Primary cells from adult rat dorsal root ganglia (containing both neurons and glia) were used in these experiments. Localisation of mTHPC was detected using fluorescence and confocal microscopy. Levels of mTHPC fluorescence were quantified using digital image analysis. Immunocytochemistry with anti-?-III-tubulin and anti-S100 was used to distinguish neuronal and glial cell populations respectively. A cell-death assay using propidium iodide was used to evaluate neural cell susceptibility to PDT following incubation with mTHPC.
The results showed that mTHPC was localised in cytoplasmic regions of neurons and glia, but was not detected in neuronal axons. Necrotic cell death was detected after PDT in these neural cell types.
These results suggest that the cells of the peripheral nervous system are susceptible to PDT-mediated necrosis, but that the sparing of nerves observed during clinical PDT may be related to the heterogeneous distribution of mTHPC within neurons
Effect of internal erosion on the mechanical behaviour of soils
A thesis submitted to the Faculty of Engineering and Built Environment, University of the Witwatersrand, Johannesburg, in fulfilment of the requirements for the Degree of Doctor of Philosophy, 2017The effect of internal erosion on the mechanical behaviour of soils was investigated experimentally, using sodium chloride grains as an analogue for erodible soil grains. With this technique, the loss of controlled quantities of finer particles could be simulated under more realistic hydro-mechanical conditions than in previous research, but within practical experimental time scales. Two experimental programs were undertaken. The first looked at general changes in volume and shear strength using a large diameter oedometer adapted to perform a punch test following salt dissolution. The second program investigated particular changes in volume and shear strength following salt dissolution using an adapted direct shear box
Previous studies have shown shear strength reductions following the loss of finer particles representing as little as 5 % of the total mass of the original soil. Findings here show shear strength can be largely unaffected if the erodible finer fraction (F) makes up less than a transition value (Ft) of approximately 10 – 15 % by mass of the original soil. This threshold represents F above which the coarser fabric is looser than at its minimum void ratio. As F increases further, finer particles increasingly hinder the coarser particles from achieving their densest packing, such that the coarser fabric remaining after finer particle loss is in a looser state than the original fabric, the remaining fabric reaching its maximum void ratio at a critical finer fraction (Fc) of approximately 25 – 35 %. For F < Fc, finer particle loss results in limited collapse of the coarser fabric and it was found that the state of this initial coarser fabric determines the shear behaviour of the soil following the loss of finer particles. The shear behaviour of initially dense specimens with F < Ft remained similar to that of a dense soil following finer particle loss, whereas shear behaviour of initially dense specimens with Ft < F < Fc approached that of a loose soil as F increased. Soils with higher internal filter ratios (D15c/D85f) were found to have higher values of Ft and Fc.
Soils with F > Fc, settled and weakened significantly following finer particle loss, reflecting the load-bearing role finer particles play in this case. This load bearing nature of the finer particles in soils with F > Fc decreases the risk of internal erosion.CK201
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Differences in sensitivity to mTHPC-mediated photodynamic therapy of neurons, glial cells and MCF7 cells in a 3-dimensional cell culture model
The effect of photodynamic therapy (PDT) on the cells of the nervous system is an important consideration in the treatment of tumours that are located within or adjacent to the brain, spinal cord and peripheral nerves. Previous studies have reported the sparing of nerves during PDT using meta-tetrahydroxyphenylchlorin (mTHPC, Foscan®) in patients and in animal models. The aim of this study was to investigate the effects of mTHPC on key nervous system cells using a 3-dimensional cell culture system for the accurate detection of differences in sensitivity
Alfabetska suspenzija u glagoljskim i ćirilskim rukopisima
This article deals with a type of abbreviation, here termed ‘alphabetic suspension’, which relies on the fact that the names of letters in the Glagolitic and Cyrillic alphabets were meaningful words, which could therefore be shortened, when they occurred in continuous text, to their initials. It reviews the evidence for alphabetic suspension in the sources available to the author, and concludes that it would be useful if the temporal and local distribution of alphabetic suspension in the Glagolitic and Cyrillic traditions could be established in more detail, because its use serves to distinguish individual scribes and could help to date manuscripts, to identify scribal schools and to cast light on their activities.ALFABETSKA SUSPENZIJA U GLAGOLJSKIM I ĆIRILSKIM RUKOPISIMA
Članak govori o specifi čnom tipu kraćenja koji se ovdje označava izrazom “alfabetska suspenzija”, a temelji se na činjenici da su nazivi slova i u glagoljici i u ćirilici bili smislene riječi te je postojala mogućnost da se u tekstu takve riječi skrate samo na početno slovo. U članku je razmotrena dokazna građa o alfabetskoj suspenziji u izvorima dostupnim autorici. Zaključeno je da bi bilo korisno utvrditi točniju vremensku i zemljopisnu distribuciju alfabetske suspenzije u glagoljskoj i ćirilskoj tradiciji, jer je na temelju uporabe takvih kratica moguće razlikovati pojedinačne prepisivače i eventualno datirati rukopise, identifi cirati pisarske škole i osvijetliti njihovu djelatnost
Новгородские антифонные псалтыри: орфографические особенности и текстологическое значение
The thirteenth-century Novgorod antiphonal psalters were written for liturgical use by two choirs or readers in alternation; consequently each of them contains an incomplete version of the psalms, and they complement each other only in part. Nevertheless, they are of interest both in relation to the development of Church Slavonic norms of orthography and orthoepy as well as from a textological standpoint. In one of them, the older of the two, the infiltration of dialect pronunciation into the Novgorod variety of Church Slavonic can be detected (a list of the various different examples of cokan′e in this manuscript is provided in the appendix). On the basis of an analysis of the variant readings found in both manuscripts or attested in either of the two sources, it is demonstrated that they belong to Redaction II of the Church Slavonic translation of the psalms, and that they are important witnesses to the dissemination of this redaction among the East Slavs up to the end of the thirteenth century.Новгородские антифонные псалтыри XIII века предназначены для богослужебного исполнения попеременно двумя хорами или чтецами, поэтому каждая из них содержит неполный текст псалмов, и они дополняют друг друга лишь частично. Тем не менее они представляют интерес и в отношении нормирования церковнославянской орфографии и орфоэпии, и с точки зрения текстологии. В одной, более древней, из них прослеживается проникновение диалектного произношения в новгородскую разновидность церковнославянского языка (в приложении дается список разнообразных примеров цоканья в этой рукописи). На основе анализа разночтений, общих для обеих рукописей или засвидетельствованных в одной или другой из них, доказывается их принадлежность ко второй редакции церковнославянского перевода псалмов, а тем самым их ценность для истории распространения этой редакции среди восточных славян до конца XIII века
Zapažanja o liturgijskom psaltiru u MS Canon. Liturg. 172 (Bodleyanska knjižnica, Oxford)
This paper examines presentational and textual peculiarities of the liturgical psalter in the breviary contained in the Glagolitic MS Canon. liturg. 172 in the Bodleian Library. It argues that they demonstrate a heavy reliance on memorization of text, seem to reflect distinctive liturgical practice, and imply that the manuscript was written for a specific user.U tekstu su analizirane strukturne i tekstološke posebnosti psaltira u brevijarskom dijelu glagoljskog rukopisa Canon. liturg. 172 koji se čuva u Bodleyevoj biblioteci. Na osnovi tih posebnosti iznose se dokazi o učestalom korištenju psaltira prilikom učenja teksta napamet i osobnoj liturgijskoj praksi te se ukazuje na mogućnost da je rukopis bio namijenjen specifičnom korisniku
Seed Business Management in Africa
Seed industry, Seed production, Trade, Commodity markets, Marketing, Agribusiness, Crop Production/Industries, E10, E20, E21, E70, E73, F03,
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