303 research outputs found

    The institutionalization of the responsibility to protect

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    Radio-frequency circular integrated inductors sizing optimization using bio-inspired techniques

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    In this article, a comparative study is accomplished between three of the most used swarm intelligence (SI) techniques; namely artificial bee colony (ABC), ant colony optimization (ACO), and particle swarm optimization (PSO) to carry out the optimal design of radio-frequency (RF) spiral inductors, the three algorithms are applied to the cost function of RF circular inductors for 180 nm beyond 2.50 GHz, the aim is to ensure optimal performance with less error in inductance, and a high-quality factor when compared to electromagnetic simulation. Simulation experiments are achieved and performances regarding convergence velocity, robustness, and computing time are checked. Also, this paper shows an impact study of technological parameters and geometric features on the inductance and the quality factor of the studied integrated inductor. The building method of constraints design with algorithms used has given good results and electromagnetic simulations are of good accuracy with an error of 2.31% and 4.15% on the quality factor and inductance respectively. The simulation shows that ACO provides more accuracy in circuit size and fewer errors than ABC and PSO, while PSO and ABC are better in terms of convergence velocity

    La responsabilité de protéger

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    4e de couverture : La responsabilité de protéger est un concept issu des travaux de la Commission internationale de l’intervention et de la souveraineté des États (CIISE). Établie en 2000 à l’initiative du Canada, elle a recherché à dépasser les controverses inhérentes aux débats relatifs au « droit d’intervention humanitaire ». Aux fins d’atteindre cet objectif, la Commission a forgé un nouveau concept, la « responsabilité de protéger », qui permît de concilier, plutôt qu’opposer, les notions de souveraineté et d’intervention. Depuis lors, la responsabilité de protéger a fait l’objet de vives controverses en droit international. Intégrée dans une résolution de l’Assemblée générale de l’ONU en septembre 2005, appliquée par le Conseil de sécurité lors de la crise en LIBYE de mars 2011, le concept se trouve, aujourd’hui, au centre des débats se rapportant au cadre juridique de la protection des populations civiles. La présente thèse entend examiner les différentes implications juridiques de la responsabilité de protéger, en optant pour une démarche résolument positiviste. La réflexion proposée tente d’en embrasser les différents aspects, tant conceptuels qu’opérationnels, aux fins d’aboutir à une étude globale, synthétique et actualisée du concept. Partant, une interrogation commandera l’ensemble de notre réflexion : l’émergence de la responsabilité de protéger a-t-elle, en droit international, permis une amélioration de la protection des populations civiles

    Developmental and pathological lymphangiogenesis: from models to human disease

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    The lymphatic vascular system, the body's second vascular system present in vertebrates, has emerged in recent years as a crucial player in normal and pathological processes. It participates in the maintenance of normal tissue fluid balance, the immune functions of cellular and antigen trafficking and absorption of fatty acids and lipid-soluble vitamins in the gut. Recent scientific discoveries have highlighted the role of lymphatic system in a number of pathologic conditions, including lymphedema, inflammatory diseases, and tumor metastasis. Development of genetically modified animal models, identification of lymphatic endothelial specific markers and regulators coupled with technological advances such as high-resolution imaging and genome-wide approaches have been instrumental in understanding the major steps controling growth and remodeling of lymphatic vessels. This review highlights the recent insights and developments in the field of lymphatic vascular biolog

    Incredible Role of Glycerol in Multicomponent Synthesis of 2,3-Dihydroquinazoline-4(1H)-ones and 1-Amidoalkyl-2-naphthols

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    An efficient and green synthesis of 1-amidoalkyl-2-naphthols via one-pot three-component condensation of aromatic aldehydes, acetamide and 2-naphthol in the presence of catalytic amounts of glycerosulfonic acid in glycerol as a green solvent was elaborated. Also a simple method for the one-pot three-component synthesis of 2,3-dihydroquinazoline-4(1H)-ones using of isatoic anhydride, aldehydes and ammonium acetate in the presence of glycerol as a green catalyst and solvent was described. In this light we introduced the brilliant and valuable role of glycerol in the synthesis of 2,3-dihydroquinazoline-4(1H)-ones and 1-amidoalkyl-2-naphthols
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