The Explicit Construction of Einstein Finsler Metrics with Non-Constant Flag Curvature

By using the Hawking Taub-NUT metric, this note gives an explicit construction of a 3-parameter family of Einstein Finsler metrics of non-constant flag curvature in terms of navigation representation

The efficacy and safety of 10 mg/day vortioxetine compared to placebo for adult major depressive disorder: a meta-analysis

Background: There is a growing interest in vortioxetine in major depressive disorder (MDD). Objectives: This meta-analysis aimed to assess the efficacy and safety of 10 mg/day (mg/d) vortioxetine compared to placebo for MDD in adult.Methods: Eight randomly controlled trials (RCTs) about the treatment of 10 mg/d vortioxetine in adult patients with MDD were identified and 2354 patients were included in meta-analysis.Results: According to the results, 10 mg/d vortioxetine showed significant differences in response rates (OR=1.88, 95% CI=1.40-2.53, P<0.0001), remission rates (OR=1.54, 95% CI=1.27-1.86, P<0.00001), change from baseline in Montgomery-As- berg Depression Rating Scale (MADRS) total score (SMD=-3.50, 95%CI=-4.83 to -2.17, P<0.00001), clinical global Impres- sion-Global Improvement (CGI-I) total score (SMD=-3.40, 95% CI=-4.69 to -2.11, P<0.00001), and change from baseline in Sheehan Disability Scale (SDS) total score (SMD=-2.09, 95% CI=-2.64 to -1.55, P<0.00001). But 10 mg/d vortioxetine was easier induced nausea (OR=4.18, 95% CI=3.21-5.44, P<0.00001) and constipation (OR=1.88, 95% CI=1.14 to 3.09, P=0.01).Conclusion: 10 mg/d vortioxetine was more effective, but easily induced nausea and constipation when compared to placebo for MDD in adult.Keywords: Vortioxetine, major depressive disorder, meta-analysis.

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Antimicrobial Usage and Resistance in Dairy Cattle Production

Antimicrobial resistance (AMR) has been a public health threat globally, with millions of lives lost due to AMR infections each year. The cases of AMR continue to escalate and cause devastating effect to both humans and animals. AMR contributes to high morbidity and mortality of the livestock, which results in staggering economic losses to the livestock producers. The main factor for AMR to arise in this industry is mainly due to the eagerness of livestock producers to meet high demand by using antimicrobials to promote animal growth and disease prevention. From a public health perspective, AMR in dairy cattle can also jeopardize human population due to the potential dissemination of AMR pathogens to humans via consumption of infected dairy products or direct contact with infected dairy cattle. At the current rate of unrestricted antimicrobial usage, AMR will be expedited and soon we will run out of effective treatment for even the simplest infection. World Health Organization (WHO) has issued a set of guidelines for the use of medically important antimicrobials on animals to mitigate the adverse consequences of AMR on human. Thus, this chapter will explain antimicrobial usage in dairy cattle production and the recent approaches and challenges on AMR

Minimising costs of environmental service provision: water-yield, salt-load and biodiversity targets with new tree planting in Simmons Creek Catchment, NSW, a dryland farming/grazing area.

Although dryland farming and grazing have been practiced for over 130 years in the 17,000 ha Simmons Creek catchment without surface salinity problems, the area has been identified as a significant source of salt seepage to Billabong Creek in the NSW Murray catchment. Groundwater movement and salinity levels are spatially heterogenous at Simmons Creek. Groundwater of the upper catchment is relatively fresh and seemingly unconnected with the highly saline groundwater of the lower catchment. However, fresh surface water does flow from the upper to the lower catchment. This spatial diversity provokes the question of where high-water-use forest habitats might be placed to achieve different combinations of environmental services (greater water yield, lower stream salinity and greater biodiversity) at least cost. Agro-forestry and or carbon sequestration benefits are not considered here. This paper presents methods and preliminary calculations of land use changes for least-cost delivery of these environmental service targets.Optimisation, opportunity costs, forest-habitat, environmental services, Environmental Economics and Policy,

Dynamic response analysis of rutting resistance performance of high modulus asphalt concrete pavement

In order to systematically study the rutting resistance performance of High-Modulus Asphalt Concrete (HMAC) pavements, a finite element method model of HMAC pavement was established using ABAQUS software. Based on the viscoelasticity theory of asphalt, the stress and deformation distribution characteristics of HMAC pavement were studied and compared to conventional asphalt pavement under moving loads. Then, the pavement temperature field model was established to study the temperature variation and the thermal stress in HMAC pavement. Finally, under the condition of continuous temperature variation, the creep behavior and permanent deformation of HMAC pavement were investigated. The results showed that under the action of moving loads, the strain and displacement generated in HMAC pavement were lower than those in conventional asphalt pavement. The upper surface layer was most obviously affected by outside air temperature, resulting in maximum thermal stress. Lastly, under the condition of continuous temperature change, HMAC pavement could greatly reduce the deformation of asphalt material in each surface layer compared to conventional asphalt pavement

MAX share this! Vote for us! Analysis of pre-election Facebook communication and audience reactions of Latvia’s populist party KPV LV leader Aldis Gobzems

This article analyses the communication content by the Latvian populistic party KPV LV (LETA; Re: Baltica) and the audience’s reaction, with a focus on the daily updates and live videos that were posted on Facebook (FB) prior to the 13th elections of the Saeima (Parliament of Latvia). The aim of the research is to determine the type of populism that KPV LV employed (de Wreese, 2018). The research data was collected during the pre-election period in August – September 2018, when the popularity and social media activity of the party increased. The methods employed were qualitative and quantitative content analysis. In order to identify the structure of emotions expressed in audience-created content, the online data analysis tool “Emotion Recognition Model” was used. Given that populist ideology manifests itself in specific discursive patterns (Kriesi, Papas, 2015), the data interpretation was based on theoretical findings about populism as a political communication style (Jagers, Walgrave, 2007). In order to analyze the interrelations between populist communication and its audience, this study employed theoretical literature on social media use in populist communication and on expressions of emotions in social networking sites

Finite-time synchronization of Markovian neural networks with proportional delays and discontinuous activations

In this paper, finite-time synchronization of neural networks (NNs) with discontinuous activation functions (DAFs), Markovian switching, and proportional delays is studied in the framework of Filippov solution. Since proportional delay is unbounded and different from infinite-time distributed delay and classical finite-time analytical techniques are not applicable anymore, new 1-norm analytical techniques are developed. Controllers with and without the sign function are designed to overcome the effects of the uncertainties induced by Filippov solutions and further synchronize the considered NNs in a finite time. By designing new Lyapunov functionals and using M-matrix method, sufficient conditions are derived to guarantee that the considered NNs realize synchronization in a settling time without introducing any free parameters. It is shown that, though the proportional delay can be unbounded, complete synchronization can still be realized, and the settling time can be explicitly estimated. Moreover, it is discovered that controllers with sign function can reduce the control gains, while controllers without the sign function can overcome chattering phenomenon. Finally, numerical simulations are given to show the effectiveness of theoretical results