408 research outputs found

    Optimized 4 pi spherical shell depleted uranium-water shield weights for 200 to 550-megawatt reactors

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    Optimization calculations to determine minimum 4 pi spherical-shell weights were performed at 200-, 375-, and 550-megawatt-thermal reactor power levels. Monte Carlo analyses were performed for a reactor power level corresponding to 375 megawatts. Power densities for the spherical reactor model used varied from 64.2 to 256 watts per cubic centimeter. The dose rate constraint in the optimization calculations was 0.25 mrem per hour at 9.14 meters from the reactor center. The resulting shield weights were correlated with the reactor power levels and power densities by a regression analysis. The optimum shield weight for a 375-megawatt, 160-watt-per-cubic-centimeter reactor was 202,000 kilograms

    Temporal dynamics of cerebellar and motor cortex physiological processes during motor skill learning

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    Learning motor tasks involves distinct physiological processes in the cerebellum (CB) and primary motor cortex (M1). Previous studies have shown that motor learning results in at least two important neurophysiological changes: modulation of cerebellar output mediated in-part by long-term depression of parallel fiber-Purkinje cell synapse and induction of long-term plasticity (LTP) in M1, leading to transient occlusion of additional LTP-like plasticity. However, little is known about the temporal dynamics of these two physiological mechanisms during motor skill learning. Here we use non-invasive brain stimulation to explore CB and M1 mechanisms during early and late motor skill learning in humans. We predicted that early skill acquisition would be proportional to cerebellar excitability (CBI) changes, whereas later stages of learning will result in M1 LTP-like plasticity modifications. We found that early, and not late into skill training, CBI changed. Whereas, occlusion of LTP-like plasticity over M1 occurred only during late, but not early training. These findings indicate a distinct temporal dissociation in the physiological role of the CB and M1 when learning a novel skill. Understanding the role and temporal dynamics of different brain regions during motor learning is critical to device optimal interventions to augment learning

    Multiple Motor Learning Processes in Humans: Defining Their Neurophysiological Bases

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    Learning new motor behaviors or adjusting previously learned actions to account for dynamic changes in our environment requires the operation of multiple distinct motor learning processes, which rely on different neuronal substrates. For instance, humans are capable of acquiring new motor patterns via the formation of internal model representations of the movement dynamics and through positive reinforcement. In this review, we will discuss how changes in human physiological markers, assessed with noninvasive brain stimulation techniques from distinct brain regions, can be utilized to provide insights toward the distinct learning processes underlying motor learning. We will summarize the findings from several behavioral and neurophysiological studies that have made efforts to understand how distinct processes contribute to and interact when learning new motor behaviors. In particular, we will extensively review two types of behavioral processes described in human sensorimotor learning: (1) a recalibration process of a previously learned movement and (2) acquiring an entirely new motor control policy, such as learning to play an instrument. The selected studies will demonstrate in-detail how distinct physiological mechanisms contributions change depending on the time course of learning and the type of behaviors being learned

    Minimum weight shield synthesis for space vehicles

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    Minimum weight proton shield synthesis for space vehicle

    Cerebellar–Motor Cortex Connectivity: One or Two Different Networks?

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    Anterior-posterior (AP) and posterior-anterior (PA) pulses of transcranial magnetic stimulation over the primary motor cortex (M1) appear to activate distinct interneuron networks that contribute differently to two varieties of physiological plasticity and motor behaviors (Hamada et al., 2014). The AP network is thought to be more sensitive to online manipulation of cerebellar (CB) activity using transcranial direct current stimulation. Here we probed CB-M1 interactions using cerebellar-brain inhibition (CBI) on young healthy female and male individuals. Transcranial magnetic stimulation (TMS) over the cerebellum produced maximal CBI of PA-evoked EMG responses at an inter-stimulus interval of 5ms (PA-CBI), whereas the maximum effect on AP responses was at 7ms (AP-CBI), suggesting that CB-M1 pathways with different conduction times interact with AP and PA networks. In addition, paired associative stimulation using ulnar nerve stimulation and PA TMS pulses over M1, a protocol used in human studies to induce cortical plasticity, reduced PA-CBI but not AP-CBI, indicating that cortical networks process cerebellar inputs in distinct ways. Finally, PA-CBI and AP-CBI were differentially modulated after performing two different types of motor learning tasks that are known to process cerebellar input in different ways. The data presented here are compatible with the idea that applying different TMS currents to the cerebral cortex may reveal cerebellar inputs to both the premotor cortex and M1. Overall, these results suggest there are two independent CB-M1networks that contribute uniquely to different motor behaviors

    Gamma spectral data for shielding and heating calculations

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    Gamma ray spectra tabulation following neutron absorption and inelastic scattering events in H, Be, C, O, Al, Cr, Fe, Ni, Zr, W, W isotopes, U-235, and U-23

    Los abuelos de nuestro rock

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    Los Yetis. Una bomba atómica a go go. La historia de los abuelos de nuestro rock. Diego Londoño; Pulso & Letra Editores, Instituto para el Desarrollo de Antioquia, Instituto de Cultura y Patrimonio de Antioquia, 2014, 98 págs., fotografías

    Medellín como construcción sonora

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    Libro reseñado: Medellín en canciones. Diego Londoño. Ediciones B, Bogotá, 2014, 148 pp

    Lenguaje ecléctico

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    Disturbio. Miguel Ángel Manrique. Seix Barral, colección Biblioteca Breve, Bogotá, 2009, 195 págs

    Cuarenta y cinco años de historia

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    La caja filarmónica. Varios autores; Orquesta Filarmónica de Bogotá, Bogotá, 2012, 3 ts., 427 págs
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