The Venezuelan Armed Forces in politics, 1935-1959

Bibliography: page [218]-233The purpose of this study is to analyze the political role of the Venezuelan military from the death of Gen. Juan Vicente Gomez in 1935 to the presidency of Romulo Betancourt in 1959. This analysis should contribute to a clearer understanding of the nature of military involvement in the national politics of a medium-sized Latin American nation. It should also serve as an additional case study for the comparative analysis of military politics in this hemisphere.From caudillism to militarism -- A decade of transition -- The October 18 rebellion -- The November 24 Coup d'Etat -- A decade of military rule -- The January 23 insurrection -- Back to the barracks -- The military's role redefinedDigitized at the University of Missouri--Columbia MU Libraries Digitization Lab in 2012. Digitized at 600 dpi with Zeutschel, OS 15000 scanner. Access copy, available in MOspace, is 400 dpi, grayscale

Proteins in harmony: Tuning selectivity in early drug discovery

This thesis describes the importance of being able to control the selectivity of potential drug candidates. It explains how computational models are employed to predict and rationalize compound-protein binding (affinity) and therewith, selectivity of compounds. Moreover, it shows that selectivity can purposely be tuned to target either a single protein or an entire panel of proteins. The challenges of selectivity modeling are addressed based on case studies in the sodium-dependent glucose co-transporters, G protein-coupled receptors, and kinases.Medicinal Chemistr

Biases from incorrect reflectance convolution

Reflectance, a crucial earth observation variable, is converted from hyperspectral to multispectral through convolution. This is done to combine time series, validate instruments, and apply retrieval algorithms. However, convolution is often done incorrectly, with reflectance itself convolved rather than the underlying (ir)radiances. Here, the resulting error is quantified for simulated and real multispectral instruments, using 18 radiometric data sets (N = 1799 spectra). Biases up to 5% are found, the exact value depending on the spectrum and band response. This significantly affects extended time series and instrument validation, and is similar in magnitude to errors seen in previous validation studies. Post-hoc correction is impossible, but correctly convolving (ir)radiances prevents this error entirely. This requires publication of original data alongside reflectance.InstrumentationEnvironmental Biolog

Accessible remote sensing of water

Water is all around us and is vital for all aspects of life. Studying the various compounds and life forms that inhabit natural waters lets us better understand the world around us.Remote sensing enables global measurements with rapid response and high consistency. Citizen science provides new knowledge and greatly increases the scientific and social impact of research.In this thesis, we investigate several aspects of citizen science and remote sensing of water, with a focus on uncertainty and accessibility. We improve existing techniques and develop new methods to use smartphone cameras for accessible remote sensing of water.This project has received funding from the European Union’s Horizon 2020 research and innovation programme under grant agreement No 776480 (MONOCLE).Conservation BiologyInstrumentatio

Contribution to evidence in low-vision rehabilitation: Effects of CCTV training in visually impaired patients

Rens, G.H.M.B. van [Promotor]Ringens, P.J. [Promotor]Nispen, R.M.A. van [Copromotor

Prefoveal floaters as a differential diagnosis to optic neuritis: "mouches dormantes"

This case series describes a new optical coherence tomography (OCT) specific observation relevant to the differential diagnosis of patients with suspected optic neuritis. A tiny prefoveal floater, only detectable by OCT, was found responsible for the symptoms in three patients, one of whom had been referred with unilateral delayed visual evoked potentials. This case series suggests that with increased use of OCT in routine clinical care, entoptic phenomena can be demonstrated as a relevant differential diagnosis to optic neuritis. Patients should be explained the benign nature of their symptoms

Dive into the unknown: embracing uncertainty to advance aquatic remote sensing

Uncertainty is an inherent aspect of aquatic remote sensing, originating from sources such as sensor noise, atmospheric variability, and human error. Although many studies have advanced the understanding of uncertainty, it is still not incorporated routinely into aquatic remote sensing research. Neglecting uncertainty can lead to misinterpretations of results, missed opportunities for innovative research, and a limited understanding of complex aquatic systems. In this article, we demonstrate how working with uncertainty can advance remote sensing through three examples: validation and match-up analysis, targeted improvement of data products, and decision-making based on information acquired through remote sensing. We advocate for a change of perspective: the uncertainty inherent in aquatic remote sensing should be embraced, rather than viewed as a limitation. Focusing on uncertainty not only leads to more accurate and reliable results but also paves the way for innovation through novel insights, product improvements, and more informed decision-making in the management and preservation of aquatic ecosystems.Environmental Biolog