The Colonized and the Wrong of Colonialism

In “What's Wrong with Colonialism,” Lea Ypi argues that the distinctive wrong of colonialism should be understood as the failure of the colonial relationship to extend equal and reciprocal terms of political association to the colonized. Laura Valentini argues that Ypi's account fails. Her argument targets an ambiguity in Ypi's account of the relata of the colonial relationship. Either Ypi's view is that the members of the colonized group are, as individuals, denied an equal and reciprocal political relationship to the colonizer, or Ypi's view is that the colonized individuals form a collective agent and that it is denied an equal and reciprocal relationship to the colonizer. According to Valentini, both options face insurmountable difficulties. This paper argues that Valentini sets up a false dilemma: the third option is to think of the colonizer as relating in an unequal and nonreciprocal way to the plurality of people subjected to colonial rule. This view, I argue, avoids Valentini's objections, but it also raises new questions about how we are to understand the distinctive wrong of colonialism

Attitudinal social norms

On Bicchieri's view, social norms most centrally involve a pattern of preferences among the members of a relevant population; according to Brennan, Eriksson, Goodin, and Southwood, social norms most centrally involve patterns of normative attitudes among the members of a given group. This paper argues, first, that social norms can require attitudes as well as behaviour, and, second, that the existence of such attitudinal social norms speaks in favour of the preference-based view and against the normative attitudes-based view

Stratified social norms

This article explains how social norms can help to distinguish and understand a range of different kinds of social inequality and social hierarchy. My aim is to show how the literature on social norms can provide crucial resources to relational egalitarianism, which has made social equality and inequality into a central topic of contemporary normative political theorizing. The hope is that a more discriminating and detailed picture of different kinds of social inequality will help relational egalitarians move beyond a discussion of the justice or injustice of social equality as a single general category

Political Liberalism and Political Community

We provide a justification for political liberalism’s Reciprocity Principle, which states that political decisions must be justified exclusively on the basis of considerations that all reasonable citizens can reasonably be expected to accept. The standard argument for the Reciprocity Principle grounds it in a requirement of respect for persons. We argue for a different, but compatible, justification: the Reciprocity Principle is justified because it makes possible a desirable kind of political community. The general endorsement of the Reciprocity Principle, we will argue, helps realize joint political rule and relationships of civic friendship. The main obstacle to the realization of these values is the presence of reasonable disagreement about religious, moral, and philosophical issues characteristic of liberal societies. We show the Reciprocity Principle helps to overcome this obstacle

Sub-Typing of Rheumatic Diseases Based on a Systems Diagnosis Questionnaire

The future of personalized medicine depends on advanced diagnostic tools to characterize responders and non-responders to treatment. Systems diagnosis is a new approach which aims to capture a large amount of symptom information from patients to characterize relevant sub-groups.49 patients with a rheumatic disease were characterized using a systems diagnosis questionnaire containing 106 questions based on Chinese and Western medicine symptoms. Categorical principal component analysis (CATPCA) was used to discover differences in symptom patterns between the patients. Two Chinese medicine experts where subsequently asked to rank the Cold and Heat status of all the patients based on the questionnaires. These rankings were used to study the Cold and Heat symptoms used by these practitioners.The CATPCA analysis results in three dimensions. The first dimension is a general factor (40.2% explained variance). In the second dimension (12.5% explained variance) 'anxious', 'worrying', 'uneasy feeling' and 'distressed' were interpreted as the Internal disease stage, and 'aggravate in wind', 'fear of wind' and 'aversion to cold' as the External disease stage. In the third dimension (10.4% explained variance) 'panting s', 'superficial breathing', 'shortness of breath s', 'shortness of breath f' and 'aversion to cold' were interpreted as Cold and 'restless', 'nervous', 'warm feeling', 'dry mouth s' and 'thirst' as Heat related. 'Aversion to cold', 'fear of wind' and 'pain aggravates with cold' are most related to the experts Cold rankings and 'aversion to heat', 'fullness of chest' and 'dry mouth' to the Heat rankings.This study shows that the presented systems diagnosis questionnaire is able to identify groups of symptoms that are relevant for sub-typing patients with a rheumatic disease

Lipidomics Reveals Multiple Pathway Effects of a Multi-Components Preparation on Lipid Biochemistry in ApoE*3Leiden.CETP Mice

Background: Causes and consequences of the complex changes in lipids occurring in the metabolic syndrome are only partly understood. Several interconnected processes are deteriorating, which implies that multi-target approaches might be more successful than strategies based on a limited number of surrogate markers. Preparations from Chinese Medicine (CM) systems have been handed down with documented clinical features similar as metabolic syndrome, which might help developing new intervention for metabolic syndrome. The progress in systems biology and specific animal models created possibilities to assess the effects of such preparations. Here we report the plasma and liver lipidomics results of the intervention effects of a preparation SUB885C in apolipoprotein E3 Leiden cholesteryl ester transfer protein (ApoE*3Leiden.CETP) mice. SUB885C was developed according to the principles of CM for treatment of metabolic syndrome. The cannabinoid receptor type 1 blocker rimonabant was included as a general control for the evaluation of weight and metabolic responses. Methodology/Principal Findings: ApoE*3Leiden.CETP mice with mild hypercholesterolemia were divided into SUB885C-, rimonabant- and non-treated control groups. SUB885C caused no weight loss, but significantly reduced plasma cholesterol (-49%, p <0.001), CETP levels (-31%,

The Self-Respect of Democratic People

According to Matthew Kramer’s aspirational perfectionism, the state is permitted to provide funding for the arts, sciences, and culture with the aim of securing the warranted self-respect of all citizens. This paper argues that although Kramer is right to think that the state has an important role to play in the economy of recognition, his conception of this role is mistaken. I argue, first, that Kramer’s exclusive focus on warrant for self-respect obscures the importance of social phenomena such as stigma, marginalization, and discrimination. Second, I argue that Kramer is mistaken in his reliance on vicarious pride to explain how the various excellences of our fellow citizens provide us with warrant for self-respect. I conclude with a brief sketch an alternative account, according to which the self-respect of citizens of democratic societies is supported by their collective creation and maintenance of just political institutions

The Self-Respect of Democratic People

According to Matthew Kramer’s aspirational perfectionism, the state is permitted to provide funding for the arts, sciences, and culture with the aim of securing the warranted self-respect of all citizens. This paper argues that although Kramer is right to think that the state has an important role to play in the economy of recognition, his conception of this role is mistaken. I argue, first, that Kramer’s exclusive focus on warrant for self-respect obscures the importance of social phenomena such as stigma, marginalization, and discrimination. Second, I argue that Kramer is mistaken in his reliance on vicarious pride to explain how the various excellences of our fellow citizens provide us with warrant for self-respect. I conclude with a brief sketch an alternative account, according to which the self-respect of citizens of democratic societies is supported by their collective creation and maintenance of just political institutions