257 research outputs found

    Enhanced Position Verification for VANETs using Subjective Logic

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    The integrity of messages in vehicular ad-hoc networks has been extensively studied by the research community, resulting in the IEEE~1609.2 standard, which provides typical integrity guarantees. However, the correctness of message contents is still one of the main challenges of applying dependable and secure vehicular ad-hoc networks. One important use case is the validity of position information contained in messages: position verification mechanisms have been proposed in the literature to provide this functionality. A more general approach to validate such information is by applying misbehavior detection mechanisms. In this paper, we consider misbehavior detection by enhancing two position verification mechanisms and fusing their results in a generalized framework using subjective logic. We conduct extensive simulations using VEINS to study the impact of traffic density, as well as several types of attackers and fractions of attackers on our mechanisms. The obtained results show the proposed framework can validate position information as effectively as existing approaches in the literature, without tailoring the framework specifically for this use case.Comment: 7 pages, 18 figures, corrected version of a paper submitted to 2016 IEEE 84th Vehicular Technology Conference (VTC2016-Fall): revised the way an opinion is created with eART, and re-did the experiments (uploaded here as correction in agreement with TPC Chairs

    High quality ultrafast transmission electron microscopy using resonant microwave cavities

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    Ultrashort, low-emittance electron pulses can be created at a high repetition rate by using a TM110_{110} deflection cavity to sweep a continuous beam across an aperture. These pulses can be used for time-resolved electron microscopy with atomic spatial and temporal resolution at relatively large average currents. In order to demonstrate this, a cavity has been inserted in a transmission electron microscope, and picosecond pulses have been created. No significant increase of either emittance or energy spread has been measured for these pulses. At a peak current of 814±2814\pm2 pA, the root-mean-square transverse normalized emittance of the electron pulses is εn,x=(2.7±0.1)⋅10−12\varepsilon_{n,x}=(2.7\pm0.1)\cdot 10^{-12} m rad in the direction parallel to the streak of the cavity, and εn,y=(2.5±0.1)⋅10−12\varepsilon_{n,y}=(2.5\pm0.1)\cdot 10^{-12} m rad in the perpendicular direction for pulses with a pulse length of 1.1-1.3 ps. Under the same conditions, the emittance of the continuous beam is εn,x=εn,y=(2.5±0.1)⋅10−12\varepsilon_{n,x}=\varepsilon_{n,y}=(2.5\pm0.1)\cdot 10^{-12} m rad. Furthermore, for both the pulsed and the continuous beam a full width at half maximum energy spread of 0.95±0.050.95\pm0.05 eV has been measured

    Mechanical cell-matrix feedback explains pairwise and collective endothelial cell behavior in vitro

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    In vitro cultures of endothelial cells are a widely used model system of the collective behavior of endothelial cells during vasculogenesis and angiogenesis. When seeded in an extracellular matrix, endothelial cells can form blood vessel-like structures, including vascular networks and sprouts. Endothelial morphogenesis depends on a large number of chemical and mechanical factors, including the compliancy of the extracellular matrix, the available growth factors, the adhesion of cells to the extracellular matrix, cell-cell signaling, etc. Although various computational models have been proposed to explain the role of each of these biochemical and biomechanical effects, the understanding of the mechanisms underlying in vitro angiogenesis is still incomplete. Most explanations focus on predicting the whole vascular network or sprout from the underlying cell behavior, and do not check if the same model also correctly captures the intermediate scale: the pairwise cell-cell interactions or single cell responses to ECM mechanics. Here we show, using a hybrid cellular Potts and finite element computational model, that a single set of biologically plausible rules describing (a) the contractile forces that endothelial cells exert on the ECM, (b) the resulting strains in the extracellular matrix, and (c) the cellular response to the strains, suffices for reproducing the behavior of individual endothelial cells and the interactions of endothelial cell pairs in compliant matrices. With the same set of rules, the model also reproduces network formation from scattered cells, and sprouting from endothelial spheroids. Combining the present mechanical model with aspects of previously proposed mechanical and chemical models may lead to a more complete understanding of in vitro angiogenesis.Comment: 25 pages, 6 figures, accepted for publication in PLoS Computational Biolog

    Changing Behaviour towards Aerobic and Strength Exercise (BASE): Design of a randomised, phase I study determining the safety, feasibility and consumer-evaluation of a remotely-delivered exercise programme in persons with multiple sclerosis

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    Background Multiple sclerosis is a chronic progressive neurological disease. Evidence attests to the benefits of exercise, guidelines for exercise in multiple sclerosis are available. Remote-delivery of exercise adherence programmes based on the exercise guidelines require urgent testing. Aims The design, and outcomes of Behaviour towards Aerobic and Strength Exercise in MS (BASE-MS), a remotely-delivered exercise training study based principles of behaviour change, will further evaluate the remote-delivery of the current exercise guidelines. Methods BASE is a 4-month clinically relevant randomised controlled trial to explore the delivery of a remotely supervised, guidelines-based exercise programme for persons with multiple sclerosis, underpinned by principles of health behaviour change. Initially, 72 persons with mild to moderate multiple sclerosis will be randomised in a 1:1:1 allocation to receive the BASE programme, or act as controls continuing usual care. On programme completion, exercise participants will be further randomised to an optimised adherence treatment or usual adherence. Our online survey assesses the primary outcome of exercise participation, and secondary outcomes of symptoms, and correlates of behaviour change at baseline, month four, month five and month eleven. Online surveys will capture coach and participant feedback to identify the contexts, mechanisms and outcomes of BASE implementation. Conclusions The research and clinical landscape for MS management must remain in-step with public health and health communication. BASE tests the remote-delivery of the current exercise guidelines for exercise in persons with MS. Safety, feasibility and evaluative outcomes will provide rich data for future remote-delivery of exercise in neurological conditions

    Theory and particle tracking simulations of a resonant radiofrequency deflection cavity in TM110_{110} mode for ultrafast electron microscopy

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    We present a theoretical description of resonant radiofrequency (RF) deflecting cavities in TM110_{110} mode as dynamic optical elements for ultrafast electron microscopy. We first derive the optical transfer matrix of an ideal pillbox cavity and use a Courant-Snyder formalism to calculate the 6D phase space propagation of a Gaussian electron distribution through the cavity. We derive closed, analytic expressions for the increase in transverse emittance and energy spread of the electron distribution. We demonstrate that for the special case of a beam focused in the center of the cavity, the low emittance and low energy spread of a high quality beam can be maintained, which allows high-repetition rate, ultrafast electron microscopy with 100 fs temporal resolution combined with the atomic resolution of a high-end TEM. This is confirmed by charged particle tracking simulations using a realistic cavity geometry, including fringe fields at the cavity entrance and exit apertures

    Direct magneto-optical compression of an effusive atomic beam for high-resolution focused ion beam application

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    An atomic rubidium beam formed in a 70 mm long two-dimensional magneto-optical trap (2D MOT), directly loaded from a collimated Knudsen source, is analyzed using laser-induced fluorescence. The longitudinal velocity distribution, the transverse temperature and the flux of the atomic beam are reported. The equivalent transverse reduced brightness of an ion beam with similar properties as the atomic beam is calculated because the beam is developed to be photoionized and applied in a focused ion beam. In a single two-dimensional magneto-optical trapping step an equivalent transverse reduced brightness of (1.0+0.8−0.4)(1.0\substack{+0.8-0.4}) ×106\times 10^6 A/(m2^2 sr eV) was achieved with a beam flux equivalent to (0.6+0.3−0.2)(0.6\substack{+0.3-0.2}) nA. The temperature of the beam is further reduced with an optical molasses after the 2D MOT. This increased the equivalent brightness to (6+5−2)(6\substack{+5-2})×106\times 10^6 A/(m2^2 sr eV). For currents below 10 pA, for which disorder-induced heating can be suppressed, this number is also a good estimate of the ion beam brightness that can be expected. Such an ion beam brightness would be a six times improvement over the liquid metal ion source and could improve the resolution in focused ion beam nanofabrication.Comment: 10 pages, 8 figures, 1 tabl

    Dual mode microwave deflection cavities for ultrafast electron microscopy

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    This paper presents the experimental realization of an ultrafast electron microscope operating at a repetition rate of 75 MHz based on a single compact resonant microwave cavity operating in dual mode. This elliptical cavity supports two orthogonal TM110_{110} modes with different resonance frequencies that are driven independently. The microwave signals used to drive the two cavity modes are generated from higher harmonics of the same Ti:Sapphire laser oscillator. Therefore the modes are accurately phase-locked, resulting in periodic transverse deflection of electrons described by a Lissajous pattern. By sending the periodically deflected beam through an aperture, ultrashort electron pulses are created at a repetition rate of 75 MHz. Electron pulses with τ=(750±10)\tau=(750\pm10) fs pulse duration are created with only (2.4±0.1)(2.4\pm0.1) W of microwave input power; with normalized rms emittances of ϵn,x=(2.1±0.2)\epsilon_{n,x}=(2.1\pm0.2) pm rad and ϵn,y=(1.3±0.2)\epsilon_{n,y}=(1.3\pm0.2) pm rad for a peak current of Ip=(0.4±0.1)I_p=(0.4\pm0.1) nA. This corresponds to an rms normalized peak brightness of Bnp,rms=(7±1)×106B_{np,\textrm{rms}}=(7\pm1)\times10^6 A/m2^2 sr V, equal to previous measurements for the continuous beam. In addition, the FWHM energy spread of ΔU=(0.90±0.05)\Delta U = (0.90\pm0.05) eV is also unaffected by the dual mode cavity. This allows for ultrafast pump-probe experiments at the same spatial resolution of the original TEM in which a 75 MHz Ti:Sapphire oscillator can be used for exciting the sample. Moreover, the dual mode cavity can be used as a streak camera or time-of-flight EELS detector with a dynamic range >104>10^4

    Design and characterization of dielectric filled TM110_{110} microwave cavities for ultrafast electron microscopy

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    Microwave cavities oscillating in the TM110_{110} mode can be used as dynamic electron-optical elements inside an electron microscope. By filling the cavity with a dielectric material it becomes more compact and power efficient, facilitating the implementation in an electron microscope. However, the incorporation of the dielectric material makes the manufacturing process more difficult. Presented here are the steps taken to characterize the dielectric material, and to reproducibly fabricate dielectric filled cavities. Also presented are two versions with improved capabilities. The first, called a dual-mode cavity, is designed to support two modes simultaneously. The second has been optimized for low power consumption. With this optimized cavity a magnetic field strength of 2.84 ±\pm 0.07 mT was generated at an input power of 14.2 ±\pm 0.2 W. Due to the low input powers and small dimensions, these dielectric cavities are ideal as electron-optical elements for electron microscopy setups

    Effective and Efficient Stand Magnifier Use in Visually Impaired Children

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    Contains fulltext : 167758.pdf (publisher's version ) (Open Access)PURPOSE: The main objective of this study was to analyze the effectiveness and efficiency of magnifier use in children with visual impairment who did not use a low vision aid earlier, in an ecologically valid goal-directed perceptuomotor task. METHODS: Participants were twenty-nine 4- to 8-year-old children with visual impairment and 47 age-matched children with normal vision. After seeing a first symbol (an Lea Hyvarinen [LH] symbol), children were instructed to (1) move the stand magnifier as quickly as possible toward a small target symbol (another LH symbol that could only be seen by using the magnifier), (2) compare the two symbols, and (3) move the magnifier to one of two response areas to indicate whether the two symbols were identical. Performance was measured in terms of accuracy, response time, identification time, and movement time. Viewing distance, as well as hand and eye dominance while using the magnifier was assessed. RESULTS: There were no significant differences between the two groups in accuracy, reaction time, and movement time. Contrary to the prediction, children with visual impairment required less time to identify small symbols than children with normal vision. Both within-subject and between-subject variability in viewing distance were smaller in the visually impaired group than in the normally sighted group. In the visually impaired group, a larger viewing distance was associated with shorter identification time, which in turn was associated with higher accuracy. In the normally sighted group, a faster movement with the magnifier and a faster identification were associated with increasing age. CONCLUSION: The findings indicate that children with visual impairment can use the stand magnifier adequately and efficiently. The normally sighted children show an age-related development in movement time and identification time and show more variability in viewing distance, which is not found in visually impaired children. Visually impaired children seem to choose a standard but less adaptive strategy in which they primarily used their preferred hand to manipulate the magnifier and their preferred eye to identify the symbol. TRIAL REGISTRATION: Registered at http://www.trialregister.nl; NTR2380.11 p
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