REGISTRATIE VAN INTOXICATIES OP DE SPOEDGEVALLENDIENST VAN EEN UNIVERSITAIR ZIEKENHUIS TE LEUVEN, BELGIË

To approach and treat poisoned patients optimally, it is necessary to be aware of the actual poisoning characteristics and trends during the last years. The goal of this study is to examine recent evolutions and to compare them with previous data. We prospectively collected poisoning characteristics during two blocks of three months in 2011 and compared these data with historical data (1993-1996). Both studies were performed at the same emergency department of a university hospital in Leuven – Belgium. Data are compared using chi-square tests. 553 patients were included in 2011, 3167 patients during 1993 until 1996. Distribution of age comparing the recent study with the historical study, has changed significantly. Products most frequently responsible for intoxications in 2011 were alcohol, benzodiazepines and analgetics. In contrast, alcohol, benzodiazepines and carbon monoxide were most frequently registered from 1993 until 1996. Patients are discharged more often nowadays, instead of being admitted to a hospital or psychiatric institution. This study demonstrates significant and clinically relevant changes in poisoning epidemiology and provides useful information about actual poisoning characteristics.

Does epidemiology of poisoning change over time in an academic emergency department?

status: publishe

How accurate is a POC bloodgas analyser?

status: publishe

Does epidemiology of poisoning change over time in an academic emergency department?

status: publishe

18F-fluoro-2-deoxy-D-glucose positron emission tomography/computed tomography in muscle-invasive bladder cancer

Purpose of review In this narrative review, we assessed the role of(18)F-fluoro-2-deoxy-D-glucose-positron emission tomography/CT (FDG-PET/CT) in preoperative staging and response evaluation of neoadjuvant chemotherapy in muscle-invasive bladder carcinoma (MIBC), and to assess its incremental value to contrast-enhanced (CE)CT and MRI in terms of patient management at initial diagnosis and detection of recurrence. Recent findings A literature search in PubMed yielded 46 original reports, of which 15 compared FDG-PET/CT with CECT and one with MRI. For primary tumor assessment, FDG-PET/CT proved not accurate enough (13 reports;n = 7-70). For lymph node assessment, sensitivity of FDG-PET/CT is superior to CT with comparable specificity in 19 studies (n = 15-233). For detection of distant metastases, data from eight studies (n = 43-79) suggests that FDG-PET/CT is accurate, although comparative studies are lacking. Limited evidence (four studies,n = 19-50) suggests that FDG-PET/CT is not accurate for response evaluation of neoadjuvant chemotherapy. FDG-PET/CT incited change(s) in patient management in 18-68% of patients (five reports;n = 57-103). For detection of recurrence, seven studies (n = 29-287) indicated that FDG-PET/CT is accurate. Most studies evaluated FDG-PET/CT for lymph node assessment and reported higher sensitivity than CT, with comparable specificity. FDG-PET/CT showed incremental value to CECT for recurrence and often incited change(s) in patient management